Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 23 of 23 results

Project Title
Project Status
Project Type

Text-Messaging Telehealth and Contingency Management for Opioid Use Disorder Treatment Engagement

University of Pennsylvania
| Pennsylvania
Mucio Delgado, MD, MS
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Community-Based, Family-Centered, Trauma-Informed Approach to Timely Detection and Management of Early Postpartum Hypertension

Yale School of Public Health
| Connecticut
Rafael Perez-Escamilla, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Help People Quit Smoking

University of Florida
| Florida
Jesse Dallery, PhD
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Testing the Effectiveness of a Text-Message-Based Home Monitoring Program and Oxygen Monitoring for Patients with COVID-19 -- The COVID Watch Study

University of Pennsylvania Perelman School of Medicine
| Pennsylvania
Mucio Kit Delgado, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Ways to Promote Quitting Smoking for People Referred for Lung Cancer Screenings

University of Pennsylvania
| Pennsylvania
Scott Halpern, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Comparing Ways for Patients, Doctors, and Clinics to Improve Blood Pressure Control -- A PCORnet® Study

University of California San Francisco
| California
Mark J. Pletcher, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Home- Versus Clinic-Based Phototherapy for the Treatment of Psoriasis -- The LITE Study

University of Pennsylvania
| Pennsylvania
Joel Mitchell Gelfand, MD, MS
Project Status:
In progress; Data collected
Project Type:
Research
Has Results

Comparing Essure® and Tubal Ligation to Prevent Pregnancy

Yale University
| Connecticut
Aileen M. Gariepy, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Three Treatments for Adults with Major Depression That Does Not Respond to First-Line Treatment -- The ASCERTAIN TRD Study

Massachusetts General Hospital
| Massachusetts
George Papakostas, MD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Telehealth and Clinic-Based Care for Lowering Uncontrolled High Blood Pressure

HealthPartners Institute
| Minnesota
Karen L. Margolis, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Ways to Decrease Severe Asthma Attacks among Black and Latinx Adults with Moderate to Severe Asthma -- The PREPARE Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Elliot Israel, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Ways to Reduce High Blood Pressure in Patients from Different Racial and Ethnic Groups -- The RICH LIFE Study

Johns Hopkins University
| Maryland
Lisa A. Cooper, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Medicines to Prevent Blood Clots in Patients Who Have Hip or Knee Replacement Surgery -- The PEPPER Study

Dartmouth-Hitchcock Clinic^
| New Hampshire
Vincent Domenic Pellegrini, MD
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Testing a Health Coaching Program to Help Patients with Obesity Lose Weight -- The PROPEL Study

Pennington Biomedical Research Center
| Louisiana
Peter T. Katzmarzyk, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Three Methods to Help Patients Manage Type 2 Diabetes

George Washington University
| District of Columbia
Richard Jeffrey Katz, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does a Peer Support Program Improve Satisfaction with Treatment among Patients with Obstructive Sleep Apnea?

University of Ariona
| Arizona
Sairam Parthasarathy, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Cardiac Rehabilitation at Home or in a Clinic after Hospitalization

University of California San Francisco
| California
Mary Whooley, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Helping Patients with Chronic Pain Get Non-medicine Treatments

Inflexxion, Inc.
| Massachusetts
Traci C. Green, PhD, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Evaluating a Patient-Centered Medical Home for Patients Receiving Dialysis for Kidney Disease

University of Illinois at Chicago
| Illinois
Denise Hynes, MPH, PhD, RN
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Do People with Obesity Lose Weight When Offered a Choice of Research-Based Weight-Loss Treatment by Their Doctors?

Denver Health and Hospital Authority
| Colorado
Daniel Bessesen, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Examining Home Visits from Community Health Workers to Help Patients Manage Asthma Symptoms

Seattle-King County Public Health Department
| Washington
James Stout, MD, MPH^
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does a Stress Management Program for African-American Parents Increase Asthma Symptom-Free Days for Their Children? -- The BEAMS Study

Children's Research Institute
| District of Columbia
Stephen J. Teach, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Effects of Surgery, Radiation Therapy, and Active Surveillance on Men with Localized Prostate Cancer -- The CEASAR Study

Vanderbilt University
| Tennessee
David Penson, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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