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State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 76 results

Project Title
Project Status
Project Type

Develop Novel Methods to Identify and Characterize Family Relationships from Electronic Health Data

University of Colorado Denver
| Colorado
Toan Ong, PhD, and Lisa Schilling, MD, MSPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Can A/B Testing Be Adapted into an Ethical and Useful Approach to Patient-Centered Outcomes Research?

Memorial Sloan Kettering Cancer Center
| New York
James Flory, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Data-Adaptive Readmissions Models for Heterogeneous and Longitudinal Data

Regents of the University of Minnesota
| Minnesota
Jared Huling, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Diagnostic Tools for Quality Improvement of Machine Learning-Based Clinical Decision Support Systems

University of California, San Francisco
| California
Jean Feng, PhD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Making an Intensive Behavioral Treatment for Patients with Obesity Part of Regular Care at Primary Care Clinics

University of Colorado Anschutz Medical Campus
| Colorado
Jodi Holtrop, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Open Competition PFA: Implementation of Findings from PCORI’s Research Investments)

Fast and Robust Weighting Methods for Targeted Comparative Effectiveness Research

President and Fellows of Harvard College
| Massachusetts
Jose Zubizarreta, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Transportability of Machine Learning-Enabled Confounding Control Methods Across EHR Databases

Brigham and Women's Hospital
| Massachusetts
Richard Wyss, PhD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Promoting Informed Decision Making When Choosing between Antibiotics or Surgery for Appendicitis -- The TRIAD (Treatment Individualized Appendicitis Decision Making) Implementation Program

University of Washington
| Washington
David Flum, MD, MPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Using a Smartphone Program to Help Patients Manage Symptoms of Serious Mental Illness

University of Washington
| Washington
Dror Ben-Zeev, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Sensitivity Analysis Methods for Pragmatic Trials with Irregular and Informative Assessment Times

University of Utah
| Utah
Daniel Scharfstein, ScD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Statistical Methods for Optimizing Dynamic Patient-Level Treatment and Monitoring Strategies

Rutgers University School of Public Health
| New Jersey
Jason Roy, PhD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Improving PCOR/CER Study Methodologies in Studies with Different Respondent Types Using IRT

Brown University
| Rhode Island
Roee Gutman, PhD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Randomized Trials and Their Observational Emulations -- Benchmarking and Join Analysis

President and Fellows of Harvard College
| Massachusetts
Issa Dahabreh, MD, ScD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Causal Mediation Analysis with Machine Learning to Understand Comparative Treatment Effects

New York University
| New York
Ivan Diaz, PhD, MPH, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Improving Methods for Design and Analysis of CER with Complex Observational Healthcare Data

The University of Texas Southwestern Medical Center
| Texas
Hong Zhu, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Robust Longitudinal Causal Inference Methods with Machine Learning

Rutgers, The State University of New Jersey
| New Jersey
Liangyuan Hu, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Supporting Pain Management for Sickle Cell Disease Crisis at Infusion Centers

Johns Hopkins School of Medicine
| Maryland
Sophie Lanzkron, MD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Implementing Matching of Patients to Mental Healthcare Therapists’ Strengths

University of Massachusetts Amherst
| Massachusetts
Michael Constantino, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Using a Virtual Screening and Care Program to Increase Access to Treatment for Urinary Incontinence in Women

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
Brian Mittman, PhD, MA
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Open Competition PFA: Implementation of Findings from PCORI’s Research Investments)

Improving Instrumental Variables Methods for Non-Randomized Studies

The Trustees of The University of Pennsylvania
| Pennsylvania
Luke Keele, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Putting an Online Weight Management Program in Place in Clinical and Community Settings

Brigham and Women's Hospital
| Massachusetts
Heather J. Baer, ScD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Developing a New Method to Combine Different Types of Trial Data in Meta-Analyses

The Regents of the University of California, San Francisco
| California
Mi-Ok Kim, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Creating Guidelines for Assessing How Well Data Reflect Clinical Context

Children's Hospital of Philadelphia
| Pennsylvania
Charles Bailey, MD, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Developing Methods to Combine Data Sources for Health Research

Johns Hopkins Bloomberg School of Public Health
| Maryland
Elizabeth Stuart, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

New Methods for Planning Cluster Randomized Trials to Detect Treatment Effect Heterogeneity

Yale School of Public Health
| Connecticut
Fan Li, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

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