Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 154 results

Project Title
Project Status
Project Type
Has Results

The HERO Research Program -- A PCORnet® Project to Support Studies on COVID-19

Duke University
| North Carolina
Adrian Hernandez, MD, MHS; Emily O'Brien, PhD (HERO registry); Susanna Naggie, MD (HERO-HCQ trial)
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Using PCORnet to Track Patient-Reported Symptoms of Heart Failure

Vanderbilt University Medical Center
| Tennessee
Justin Bachmann, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

A New Natural Language Processing Method to Study Whether Patients Take Medicine as Directed

The University of Texas Health Science Center at Houston
| Texas
Kirk Roberts, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing the Safety and Effectiveness of Metformin with Other Medicines for Patients with Type 2 Diabetes and Chronic Kidney Disease

Joan and Sanford I. Weill Medical College of Cornell University
| New York
James Flory, MD, MSCE
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Ways for Patients, Doctors, and Clinics to Improve Blood Pressure Control -- A PCORnet® Study

University of California San Francisco
| California
Mark J. Pletcher, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Medicines to Treat Ulcerative Colitis and Crohn's Disease When Anti-TNF Medicines Don't Work

The University of North Carolina at Chapel Hill^
| North Carolina
Michael D. Kappelman, MD, MPH^
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Ways to Help Primary Care Providers Prescribe Opioids Safely

University of Pittsburgh
| Pennsylvania
Kevin Kraemer, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Identifying Barriers to Telehealth Home-Based Palliative Care for Patients with Serious Illness -- The HomePal Study

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
Huong Q. Nguyen, PhD, RN
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

New Methods to Improve Data Accuracy in Studies Using Electronic Health Record Data

Vanderbilt University Medical Center
| Tennessee
Bryan E. Shepherd, PhD; Pamela A. Shaw, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Understanding How to Use Single Patient Studies to Answer Patient-Identified Research Questions

Cincinnati Children’s Hospital Medical Center
| Ohio
Heather C. Kaplan, MD, MSCE; Lisa Opipari-Arrigan, PhD; Gregory M. Marcus, MD, MAS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Project Status:
Completed
Project Type:
Pipeline to Proposal, Tier I
Project Status:
Completed
Project Type:
Pipeline to Proposal, Tier I
Project Status:
Completed
Project Type:
Pipeline to Proposal, Tier I

Engaging Community Stakeholders to Improve Childhood Obesity Interventions - Tier I

FLIPANY, Florida Introduces Physical Activity and Nutrition to Youth
| Florida
Kristine Perez-Carrion, MA, MMedSci
Project Status:
Completed
Project Type:
Pipeline to Proposal, Tier I

MANOS - Hands for Mental Health: A Behavioral Health Advisory Group for Urban and Rural Hispanic Americans in Colorado - Tier I

University of Colorado-Anschutz College of Nursing
| Colorado
Tanya R. Sorrell, PhD, PMHNP-BC
Project Status:
Completed
Project Type:
Pipeline to Proposal, Tier I

Fecal Incontinence in Primary Care Consortium - Tier I

Nova Southeatern University, Master of Public Health program
| Florida
Nicole Cook, PhD, MPA
Project Status:
Completed
Project Type:
Pipeline to Proposal, Tier I

Building Networks for Comparative Research with Youth Caregivers and Older Adults - Tier I

University of North Carolina at Chapel Hill
| North Carolina
Elizabeth Olson, PhD, MA
Project Status:
Completed
Project Type:
Pipeline to Proposal, Tier I

The Bexar County Neonatal Abstinence Syndrome Collaborative - Tier I

The University of Texas Health Science Center at San Antonio
| Texas
Lisa M. Cleveland, PhD, RN, PNP-BC, IBCLC
Project Status:
Completed
Project Type:
Pipeline to Proposal, Tier I

Building the Foundation for Community-Led Research to Eliminate LGBT Cancer Disparities - Tier I

The George Washington University (GW) Cancer Institute
| District of Columbia
Mandi Pratt-Chapman, MA
Project Status:
Completed
Project Type:
Pipeline to Proposal, Tier I

Breast Cancer Survivor Health and Wellness Collaborative - Tier I

Allina Health
| Minnesota
Angie Meillier, RN, MS
Project Status:
Completed
Project Type:
Pipeline to Proposal, Tier I
Project Status:
Completed
Project Type:
Pipeline to Proposal, Tier I
Project Status:
Completed
Project Type:
Pipeline to Proposal, Tier I

Developing Patient-Driven Research to Improve the Psychiatric Care of Youth in Foster Care - Tier I

Dartmouth Trauma Interventions Research Center
| New Hampshire
Erin Barnett, PhD
Project Status:
Completed
Project Type:
Pipeline to Proposal, Tier I

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