Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 48 results

Project Title
Project Status
Project Type

A Comparative Effectiveness Study of Oral Medications Used for Migraine Prevention

Mayo Clinic Arizona
| Arizona
Todd Schwedt, B.S., M.D., M.S.
Project Status:
Awarded; In progress
Project Type:
Research

Characterizing Engagement and Equity in Research (CHEER)

University of Colorado Denver
| Colorado
Bethany Kwan, MPH, Ph.D.
Project Status:
Awarded; In progress
Project Type:
Research

Implementation and Interaction of Clinician and Patient-facing Tools Aiming to Intensify Neurohormonal Medicines for Heart Failure With Reduced Ejection Fraction

University of Colorado Denver
| Colorado
Larry Allen, M.D., M.S.
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Evaluating Caregiver Involvement in Primary Care-Based Brief Interventions for Adolescent Alcohol Use Problems

Trustees of Indiana University
| Indiana
Zachary Adams, Ph.D.
Project Status:
Awarded; Contract pending
Project Type:
Research

Measuring Co-Creation During the Engagement Process in Research: A Pathway Forward

University of Colorado Denver
| Colorado
Monica Perez Jolles, Ph.D., M.A.
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Ways to Reduce Overuse of Antibiotics among Children with Ear Infections -- The DIsAPEAR Study

Denver Health and Hospital Authority
| Colorado
Holly Frost, M.D.
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

A Comparison of Two School-Based Interventions to Manage Anxiety in Autistic Students

University of Colorado Denver
| Colorado
Judy Reaven, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Develop Novel Methods to Identify and Characterize Family Relationships from Electronic Health Data

University of Colorado Denver
| Colorado
Toan Ong, PhD, and Lisa Schilling, MD, MSPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Comparing Three Ways to Treat Anxiety in Patients Who Go to the Emergency Room with Low-Risk Chest Pain

Trustees of Indiana University
| Indiana
Paul Musey, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Improve Communication between Healthcare Teams and People with a Communication Disability

University of Colorado Denver
| Colorado
Megan A. Morris, PhD, MPH, CCC-SLP
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Three Ways to Start Taking Medicine for Opioid Use Disorder

University of Colorado Anschutz Medical Campus
| Colorado
Linda Zittleman, MPH, MS
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Does Personalized Risk Information Help Patients and Doctors Make Informed Decisions about Colorectal Cancer Screening?

Indiana University
| Indiana
Peter H. Schwartz, MD, PhD, MA
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Do Public Deliberation Methods Help Improve the Informed Consent Process for Research on Sensitive Topics?

Trustees of Indiana University
| Indiana
Amelia S. Knopf, PhD, MPH, BSN
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Developing an Incremental Privacy-Preserving Record Linkage Method to Improve Data Sharing and Data Quality

Anschutz Medical Campus - University of Colorado Denver
| Colorado
Toan Ong, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Testing Methods to Link Health Data while Protecting Patient Privacy

Indiana University
| Indiana
Shaun Grannis, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Approaches for Delivering Group Medical Visits for Patients with Diabetes

University of Colorado Denver
| Colorado
Bethany M. Kwan, PhD, MSPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

MANOS - Hands for Mental Health: A Behavioral Health Advisory Group for Urban and Rural Hispanic Americans in Colorado - Tier I

University of Colorado-Anschutz College of Nursing
| Colorado
Tanya R. Sorrell, PhD, PMHNP-BC
Project Status:
Completed
Project Type:
Pipeline to Proposal, Tier I

Building a Collaborative Partnership with Super-Utilizing Female Patients with Multiple Chronic Medical Conditions including Mental Illness and Substance Use - Tier I

Denver Health
| Colorado
Debbie Rinehart, PhD, MA
Project Status:
Completed
Project Type:
Pipeline to Proposal, Tier I

Community Engagement to Improve the Transition of Tube Feeding to Oral Feeding for Children and Their Families - Tier I

University of Colorado Anschutz Medical Campus
| Colorado
Heather Aldrich, PhD
Project Status:
Completed
Project Type:
Pipeline to Proposal, Tier I
Has Results

Testing a Stepped-Care Program to Treat Emotional Distress among Patients with Lung or Head and Neck Cancer and Their Caregivers

University of Colorado Denver
| Colorado
Evelinn A. Borrayo, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Three Ways to Increase Colorectal Cancer Screening

Indiana University
| Indiana
Susan Rawl, PhD, MS, BSN
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Ways to Manage Symptoms for Patients Who Have Chronic Migraine and Frequent Medication Use -- The MOTS Trial

Mayo Clinic Arizona
| Arizona
Todd J. Schwedt, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Stopping or Continuing Use of Disease Modifying Therapies in Older Adults with Multiple Sclerosis -- The DISCOMS Trial

University of Colorado Denver
| Colorado
John R. Corboy, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Developing Effective Interventions to Achieve a Healthy Weight Among Hispanic Children Ages 0-5

Children's Hospital of Colorado
| Colorado
Deb Federspiel
Project Status:
Completed
Project Type:
Pipeline to Proposal, Tier I

Stakeholder-Driven Veterans' Suicide Protection Advisory Group

University of Colorado Denver - College of Nursing
| Colorado
Cheryl Krause-Parello, PhD, MSN
Project Status:
Completed
Project Type:
Pipeline to Proposal, Tier I

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