Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 102 results

Project Title
Project Status
Project Type

Improving In-Hospital Sleep Hygiene to Prevent and Curtail Delirium Among Older Adults

The Methodist Hospital Research Institute
| Texas
Farhaan Vahidy, Ph.D.
Project Status:
Awarded; Contract pending
Project Type:
Research

Comparative Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy

The Ohio State University
| Ohio
Maged Costantine, M.D.
Project Status:
In progress; Not yet recruiting
Project Type:
Research

DECIDE: A Comparative Effectiveness Trial of Oral Metformin versus Injectable Insulin for the Treatment of Gestational Diabetes

The Ohio State University
| Ohio
Mark Landon, M.D.
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Functional improvement in Obstructive Sleep Apnea and Chronic Obstructive Pulmonary Disease with a Telehealth LifeStyle and Exercise Intervention (FOCuSEd)

Seattle Institute for Biomedical and Clinical Research
| Washington
Laura Feemster, M.D., M.S.
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Developing a Multidimensional Measure of Adolescent Engagement in Research

Seattle Children's Research Institute
| Washington
Dimitri Christakis, M.D., MPH
Project Status:
Awarded; Contract pending
Project Type:
Research

Improving Maternal Postpartum Access to Care Through Telemedicine

University of Texas Southwestern Medical Center
| Texas
Elaine Duryea, M.D.
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Treatment with Endovascular Intervention for Stroke Patients with Existing Disability

University of Cincinnati
| Ohio
Eva Mistry, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Pacing Treatments for Patients with Heart Failure

Baylor College of Medicine
| Texas
Mihail G. Chelu, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Treat Mild Hypoxic Ischemic Encephalopathy in Infants -- The COOLPRIME Study

UT Southwestern Medical Center
| Texas
Lina Chalak, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Does Including a Health Coach in Well-Child Care Visits Improve Preventive Care for Families with Low Incomes?

Seattle Children's Research Institute
| Washington
Tumaini Coker, MD, MBA
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Comparing Ways to Prevent Migraine in Youth

Cincinnati Children's Hospital
| Ohio
Scott Powers, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Developing Methods for Analyzing Clustered Observational Data When Death is a Semi-Competing Risk

The University of Texas Southwestern Medical Center
| Texas
Hong Zhu, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Comparing Two Ways to Help Children with Complex Chronic Diseases Return Home after a Hospital Stay -- The GET2HOME Study

Cincinnati Children's Hospital Medical Center
| Ohio
Patrick Brady, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Efficacy of Pharmacologic Management of ADHD in Children and Youth with Autism Spectrum Disorder

The Research Institute at Nationwide Children's Hospital
| Ohio
Daniel Coury, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Can Pharmacists Support Primary Care Providers as Well as Pulmonologists in Treating Patients with COPD? -- The EQuiP COPD Study

VA Puget Sound Health Care System
| Washington
David Au, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Offer Social Support to Black Women during Treatment for Endometrial Cancer

University of Washington
| Washington
Kemi Doll, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Prevent Severe Hypoglycemia in Patients with Type 2 Diabetes

Kaiser Foundation Health Plan of Washington
| Washington
James Ralston, MD, MPH
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Primary Care Treatment Options for People with PTSD

University of Washington
| Washington
John Fortney, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Comparing Two Ways to Provide Safety Planning Follow-Up Support for Adults and Teens at Risk of Suicide

St. Luke's Health System
| Idaho
Anna K. Radin, DrPH, MPH
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

A New Natural Language Processing Method to Study Whether Patients Take Medicine as Directed

The University of Texas Health Science Center at Houston
| Texas
Kirk Roberts, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Treatments for Dental Cavities in Older Adults Living in Low-Income Housing

Case Western Reserve University
| Ohio
Suchitra Nelson, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Surgery and Medical Management for Treating Diverticulitis -- The COSMID Study

University of Washington
| Washington
David Flum, MD, MPH
Project Status:
In progress; Data collected
Project Type:
Research
Has Results

Comparing Inpatient Versus Outpatient Settings for Treating Teens after a Suicidal Event

Cincinnati Children's Hospital Medical Center
| Ohio
Drew Barzman, MD
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Treatment Options for Recurrent Bladder Cancer

University of Washington Office of Sponsored Programs, Department of Urology
| Washington
John Gore, MD, MS
Project Status:
In progress; Data collected
Project Type:
Research
Has Results

Comparing Two Programs to Reduce Unsafe Opioid Prescribing and Improve Outcomes among People Who Are Injured at Work -- The WOW Study

University of Washington
| Washington
Gary Franklin, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

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