Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 82 results

Project Title
Project Status
Project Type

Improving Research Partnership With Engagement Mapping: A Pilot Study to Advance Engagement Science

The Research Foundation for SUNY on behalf of Downstate Health Sciences University
| New York
Thomas Mackie, MPH, Ph.D.
Project Status:
Awarded; Contract pending
Project Type:
Research

Comparative Effectiveness of Three Health Equity Interventions to Improve Maternal Health

Trustees of Columbia University in the City of New York
| New York
Jennifer Woo Baidal, M.D., MPH
Project Status:
Awarded; Contract pending
Project Type:
Research

Comparative Effectiveness of MRD HCT and NT-DMT for Pediatric Sickle Cell Disease (WeDecide)

University of Rochester
| New York
John Horan, M.D., MPH
Project Status:
Awarded; Contract pending
Project Type:
Research

Implementation and Interaction of Clinician and Patient-facing Tools Aiming to Intensify Neurohormonal Medicines for Heart Failure With Reduced Ejection Fraction

University of Colorado Denver
| Colorado
Larry Allen, M.D., M.S.
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Revascularization Choices Among Under-Represented Groups Evaluation (The RECHARGE Program)

Joan & Sanford I. Weill Medical College of Cornell University
| New York
Mario Gaudino, M.D., Ph.D.
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Measuring Co-Creation During the Engagement Process in Research: A Pathway Forward

University of Colorado Denver
| Colorado
Monica Perez Jolles, Ph.D., M.A.
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Enhancing Stakeholder Engagement in Pediatric Research: Applying a Health Literacy and Language Lens

New York University Grossman School of Medicine
| New York
H. Shonna Yin, M.D., M.S.
Project Status:
Awarded; Contract pending
Project Type:
Research

Comparing Two Ways to Reduce Overuse of Antibiotics among Children with Ear Infections -- The DIsAPEAR Study

Denver Health and Hospital Authority
| Colorado
Holly Frost, M.D.
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

A Comparison of Two School-Based Interventions to Manage Anxiety in Autistic Students

University of Colorado Denver
| Colorado
Judy Reaven, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Adolescent-Only SBI versus Family-Based SBI in Primary Care for Adolescent Alcohol Use

Partnership to End Addiction
| New York
Aaron Hogue, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Develop Novel Methods to Identify and Characterize Family Relationships from Electronic Health Data

University of Colorado Denver
| Colorado
Toan Ong, PhD, and Lisa Schilling, MD, MSPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Can A/B Testing Be Adapted into an Ethical and Useful Approach to Patient-Centered Outcomes Research?

Memorial Sloan Kettering Cancer Center
| New York
James Flory, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Making an Intensive Behavioral Treatment for Patients with Obesity Part of Regular Care at Primary Care Clinics

University of Colorado Anschutz Medical Campus
| Colorado
Jodi Holtrop, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Open Competition PFA: Implementation of Findings from PCORI’s Research Investments)

Future Planning and Well-Being for Individuals with Intellectual Disabilities and Family Caregivers

The Feinstein Institute For Medical Research
| New York
Sophia Jan, MD, MSHP
Project Status:
In progress; Recruiting
Project Type:
Research

Pragmatic Comparative Effectiveness Using Sequential Multiple Assignment Randomized Trials

University of Rochester
| New York
Abdus Wahed, PhD, MS, MA
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Developing New Methods for Mediation Analysis Using Machine Learning

New York University
| New York
Ivan Diaz, PhD, MPH, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Comparing Two Treatments to Help Cancer Survivors with Anxiety -- The MELODY Study

Memorial Sloan Kettering Cancer Center
| New York
Jun Mao, MD, MSCE
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Telehealth and In-Person Care for Patients with Chronic Conditions

Cornell University
| New York
Rainu Kaushal, MD, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Deliver Remote Mental Health Support during the COVID-19 Pandemic

The Research Foundation For The State University of New York
| New York
Yu-Ping Chang, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Ways to Provide Follow-Up Care to Patients with Heart Failure after Hospital Discharge -- MIGHTY-Heart

The Trustees of Columbia University in the City of New York
| New York
Ruth Masterson Creber, PhD^
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Types of Prostate Biopsy

Weill Cornell Medicine
| New York
Jim C. Hu, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Programs to Increase Access to Mental Health Care for Pregnant and Postpartum Patients

The Research Foundation for The State University of New York on behalf of State University of New York Downstate Health Sciences University (SUNY DHSU)
| New York
Thomas I. Mackie, PhD, MPH
Project Status:
In progress; Enrollment complete
Project Type:
Research

Expanding the Use of a School-Based Program to Improve Executive Functioning among Students with Symptoms of Autism Spectrum Disorder or Attention Deficit/Hyperactivity Disorder

University of Colorado Denver
| Colorado
Laura G. Anthony, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Implementing Team-based Outpatient Palliative Care in Parkinson Foundation Centers of Excellence

University of Rochester
| New York
Benzi M. Kluger, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Comparing Five Treatment Approaches for Men with Prostate Cancer -- The PC CONCEPT Study

Joan & Sanford I. Weill Medical College of Cornell University
| New York
Jim C. Hu, MD, MPH, and Ronald C. Chen, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

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