Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

Keyword Search

Refine Results:

Funding Type
Expand/Collapse Facets
Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Funding Opportunity Type
Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
Year Completed
Reset Filters
Download Results

Displaying 1 - 25 of 27 results

Project Title
Project Status
Project Type

Causal Mediation Methods for Cluster-Randomized Pragmatic and Implementation Trials

Yale University
| Connecticut
Fan Li, Ph.D.
Project Status:
Awarded; Contract pending
Project Type:
Research

Delivering HOPE (Helping Women Optimize Prenatal Equity)

University of Arkansas for Medical Sciences
| Arkansas
Pearl McElfish, M.A., MBA, Ph.D.
Project Status:
Awarded; Contract pending
Project Type:
Research

Comparative Effectiveness of Racemic Ketamine versus S-Ketamine for Depression

Yale University
| Connecticut
Samuel Wilkinson, M.D.
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Peer Support Enhanced Behavioral Crisis Response Teams in the Emergency Department

Yale University
| Connecticut
Ambrose Wong, M.D., M.Ed., MS
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparative Evaluation of Telehealth Multi-Component Optimal Model (MOM) of Postpartum Care Among Rural, Low-Income, and Diverse Women

University of Arkansas for Medical Sciences
| Arkansas
Jennifer Callaghan-Koru, PhD, MBA
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Toward Improved Design and Analysis of Stepped Wedge Trials: An Estimand-Aligned and Efficiency-Focused Framework

Yale University
| Connecticut
Fan Li, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

PRESSURE POINTS: A Multilevel Team, Pragmatic Trial to Address Blood Pressure Control and Social Determinants of Health (SDOH)

Yale University
| Connecticut
Erica Spatz, M.D., MHS
Project Status:
In progress; Not yet recruiting
Project Type:
Research

A TriaL ComparIng the EffectiVEness and ToleraBility of MEdicaTions in Older Adults with STablE Angina and Multiple ChRonic Conditions: LIVE BETTER

Yale University
| Connecticut
Michael Nanna, MD, MHS
Project Status:
In progress; Recruiting
Project Type:
Research

Community-Based, Family-Centered, Trauma-Informed Approach to Timely Detection and Management of Early Postpartum Hypertension

Yale School of Public Health
| Connecticut
Rafael Perez-Escamilla, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Developing New Methods for Assessing Heterogeneity of Treatment Effect in Cluster Randomized Trials

Yale School of Public Health
| Connecticut
Fan Li, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research
Has Results

Self-Management in Older Adults with Chronic Heart Failure -- The iCOACH Study

University of Arkansas for Medical Sciences
| Arkansas
Judy Weber, PhD, RD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparing Standard and Family Diabetes Self-Management Education for Improving Diabetes Outcomes

University of Arkansas for Medical Sciences
| Arkansas
Pearl A. McElfish, PhD, MBA
Project Status:
In progress; Enrollment complete
Project Type:
Research

Advancement of PCORnet Infrastructure: Data Linkage Project with Aetna Affiliate Healthagen, LLC

Healthagen, LLC
| Connecticut
Cheryl Walraven, PhD
Project Status:
Completed
Project Type:
Research Infrastructure

Comparing Two Ways to Provide Pregnant Women with Prenatal Care and Treatment for Opioid Use Disorder

Yale University School of Medicine
| Connecticut
Ariadna Forray
Project Status:
In progress; Data collected
Project Type:
Research
Has Results

Comparing Two Ways to Help Sexual and Gender Minority Men Who Have Been Sexually Abused Reduce Depression and Increase Mental Health Treatment Engagement

Yale University
| Connecticut
Joan M. Cook, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Essure® and Tubal Ligation to Prevent Pregnancy

Yale University
| Connecticut
Aileen M. Gariepy, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Programs for Weight Loss among Marshallese Adults Living in the United States

University of Arkansas for Medical Sciences
| Arkansas
Pearl McElfish, PhD, MS, MBA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Developing New Statistical Methods for Clinical Studies Where Patients Choose Their Treatments

Yale University
| Connecticut
Denise Esserman, MS, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

HealthCore-Anthem Research Network (HCARN)

Health Core, Inc.
| Delaware
Kevin Haynes, MS, PhrmD
Project Status:
Completed
Project Type:
PCORnet® Initiative on Health Plan/System Data Partnerships (A Stepwise Approach to Collaboration)
Has Results

Comparing Treatment for Ductal Carcinoma In Situ (DCIS) with or without Sentinel Lymph Node Biopsy

Yale University
| Connecticut
Shiyi Wang, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Developing Methods to Link Patient Records across Data Sets that Preserve Patient Privacy

HealthCore
| Delaware
Kevin Haynes, PharmD, MSCE
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

In-Home versus Phone-Based Care for Older Adults with Dementia, Depression, or Delirium

University of Connecticut School of Medicine
| Connecticut
Richard Fortinsky, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Developing and Testing a Type 2 Diabetes Education Program Adapted for Marshallese Culture

University of Arkansas for Medical Sciences
| Arkansas
Peter O. Kohler, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does a Peer-Led Program with Wellness Coaching Improve Wellness among People with Serious Mental Illness?

Yale University
| Connecticut
Chyrell Bellamy, PhD, MSW
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Pilot Project: Working With Patients and Experts to Create a Survey about the Burdens of Living with a Rare Disease

University of Arkansas for Medical Sciences^
| Arkansas
Pamela H. Williams, JD, PhD, RN
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

What's Happening at PCORI?

The Patient-Centered Outcomes Research Institute sends weekly emails about opportunities to apply for funding, newly funded research studies and engagement projects, results of our funded research, webinars, and other new information posted on our site.

Subscribe to PCORI Emails
Hand pointing to email icon