Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 73 results

Project Title
Project Status
Project Type
Has Results

Comparing Two Ways to Treat Depression among Pregnant Women and New Mothers with Low Incomes

Boston Medical Center
| Massachusetts
Michael Silverstein, MD, MPH; Caroline J Kistin, MD, MSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Programs for Weight Loss among Marshallese Adults Living in the United States

University of Arkansas for Medical Sciences
| Arkansas
Pearl McElfish, PhD, MS, MBA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Approaches to Help Patients and Doctors Talk about Chronic Pain Treatments -- Voices in Pain Care

Cedars-Sinai Medical Center
| California
Brennan Spiegel, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Three Medicines to Prevent Blood Clots in Patients Who Need Long-Term Blood-Thinning Treatment -- The COVET Trial

Duke University
| North Carolina
Thomas L. Ortel, MD, PhD
Project Status:
Terminated
Project Type:
Research
Has Results

Understanding How to Use Single Patient Studies to Answer Patient-Identified Research Questions

Cincinnati Children’s Hospital Medical Center
| Ohio
Heather C. Kaplan, MD, MSCE; Lisa Opipari-Arrigan, PhD; Gregory M. Marcus, MD, MAS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®

Engaging Patients and Providers in Collaborative Communication on HPV Vaccination (EPPIC-HPV)

University of New Mexico Main Campus
| New Mexico
Gill Woodall, PhD
Project Status:
Terminated
Project Type:
Research
Has Results

Helping Women with Breast Cancer Choose between Surgical Treatment Options

Dartmouth College
| New Hampshire
Glyn Elwyn, MD, PhD, MSc^
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does Treating Genital Herpes during Pregnancy Improve Birth Outcomes?

Kaiser Foundation Research Institute
| California
De-Kun Li, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Benefits and Harms of Different Long-Term Treatments for Blood Clots -- The DARE Warfarin Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Katsiaryna Bykov, PharmD, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Three Treatments for Adults with Major Depression That Does Not Respond to First-Line Treatment -- The ASCERTAIN TRD Study

Massachusetts General Hospital
| Massachusetts
George Papakostas, MD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Managing Long-Term Low Back Pain to Improve Health and Reduce Reliance on Opioid Medicines: Comparing Mindfulness Meditation and Cognitive Behavioral Therapy -- Strategies To Assist with Management of Pain (STAMP)

University of Wisconsin-Madison
| Wisconsin
Bruce Barrett
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Ways to Help Veterans Manage Chronic Pain -- The VOICE Study

University of Minnesota Twin Cities
| Minnesota
Erin Krebs, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing the Safety and Effectiveness of Different Medicines to Treat Multiple Sclerosis -- The COMBAT-MS Study

Karolinska Institute (Sweden)
| N/A
Fredrik Piehl, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing the Effectiveness of Breast Cancer Screening and Diagnostic Tests among Women with Different Breast Densities -- The BCSC-ADVANCE Study

University of California, Davis
| California
Diana L. Miglioretti, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Does a Web-Based Decision Aid Help Patients and Their Doctors Decide How to Treat Hip and Knee Arthritis?

Northwestern University^
| Illinois
Patricia D. Franklin, MD, MBA, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Two Ways to Provide Care for Adults Who Experience Intimate Partner Violence and Depression

University of Rochester
| New York
Catherine Cerulli, JD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Treatment for Ductal Carcinoma In Situ (DCIS) with or without Sentinel Lymph Node Biopsy

Yale University
| Connecticut
Shiyi Wang, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Testing the Effectiveness of Adding Group Therapy to Home Visiting Services on Reducing Postpartum Depression in Women with Low Incomes

Northwestern University
| Illinois
Darius Tandon, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Ways to Improve Depression Symptoms among Adults who Identify as LGBTQ+ -- The RADD Study

University of California, Los Angeles
| California
Bowen Chung, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Treatment Options for Women with Low-Risk Ductal Carcinoma In Situ (DCIS) -- The COMET Study

Alliance for Clinical Trials in Oncology Foundation
| Illinois
Shelley Hwang, MD, MPH
Project Status:
In progress; Enrollment complete
Project Type:
Research

Helping People with Serious Mental Illness Stop Smoking

Massachusetts General Hospital
| Massachusetts
Eden Evins, MD, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Ways to Ask Patients about Sexual Orientation and Gender Identity in the Emergency Room -- The EQUALITY Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Adil Haider, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Testing Tablet-Based Software to Help Reduce Hospice Patients' Pain

University of Illinois at Chicago
| Illinois
Robert E. Molokie, MD^
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Is Breast MRI Better at Finding Second Breast Cancers than Mammograms Alone for Breast Cancer Survivors?

Kaiser Permanente Washington Health Research Institute^
| Washington
Karen Joanne Wernli, PhD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Can an Online Program Help Women with a History of Preeclampsia Reduce Their Risk of Heart Disease?

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Janet Rich-Edwards, MPH, ScD, and Ellen W. Seely, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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