Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Funding Opportunity Type
Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 20 of 20 results

Project Title
Project Status
Project Type

Comparing Two Types of Medicine for Pain after Surgery -- The CARES Trial

University of Michigan
| Michigan
Mark Bicket MD, PHD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Treat Patients with Rheumatoid Arthritis -- The RA-PRO PRagmatic Trial (RA-PROPR)

The University of Alabama at Birmingham
| Alabama
Jasvinder Singh, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Treat Children with Inactive Spondyloarthritis -- The BACK-OFF JSpA Study

Children's Hospital of Philadelphia
| Pennsylvania
Pamela Weiss, MD, AB
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing the Effect of Adding Acupuncture and Pain Counseling to Usual Care on Reducing Pain among Patients with Cancer -- The PRACXIS Study

University of California, San Francisco
| California
Maria Chao, DrPH, MPA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Medicines for Adults with Myasthenia Gravis -- The PROMISE-MG Study

Duke University
| North Carolina
Donald B. Sanders, MD, and Pushpa Narayanaswami, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Types of Blood Thinners to Prevent Blood Clots in Patients with Cancer -- The CANVAS Trial

Alliance for Clinical Trials in Oncology Foundation
| Illinois
Deborah Schrag, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Effects of Different Surgical Treatments on Quality of Life for Patients with Obesity

Massachusetts General Hospital
| Massachusetts
Matthew Hutter, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Three Ways to Start Treatment for Patients with Polyarticular Juvenile Idiopathic Arthritis -- The STOP-JIA Trial

Hackensack University Medical Center
| New Jersey
Yukiko Kimura, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Two Ways of Treating Rheumatoid Arthritis When Patients Are in Remission -- The STARA Study

Georgetown University
| District of Columbia
Florina Constantinescu, MD, PhD^
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Treatments for Improving Physical Function in Patients Who Had Knee Replacement Surgery

University of Pittsburgh at Pittsburgh
| Pennsylvania
Sara R. Piva, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

How Do Preferences for Treatment Change after Patients with Lung Cancer Start Chemotherapy?

University of Nebraska Medical Center
| Nebraska
KM Islam, MBBS, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

A Patient Decision Aid to Help Heavy Smokers Make Decisions about Lung Cancer Screening

University of Texas MD Anderson Cancer Center
| Texas
Robert J. Volk, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Effects of Two Types of Epidural Shots on Pain and Physical Ability in Older Adults with Lumbar Spinal Stenosis

University of Washington
| Washington
Janna Friedly, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Physical Therapy, Internet-Based Exercise Training, and No Therapy for Knee Osteoarthritis

University of North Carolina Chapel Hill^
| North Carolina
Kelli D. Allen, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

How Often Should Patients with Lung Cancer Have Imaging Tests after Surgery?

Alliance for Clinical Trials in Oncology Foundation
| Illinois
Benjamin David Kozower, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Programs to Improve Disability, Pain, and Health among Patients Who Have Had Back Surgery

Vanderbilt University Medical Center
| Tennessee
Kristin Archer, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Surgical Treatments for Cervical Spondylotic Myelopathy -- The CSM-S Trial

Lahey Clinic, Inc.
| Massachusetts
Zoher Ghogawala, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does Helping Patients with Cancer Manage Their Symptoms at Home Improve Their Quality of Life?

University of South Florida
| Florida
Susan McMillan, NP, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Can Using Patient Reports of Low Back Pain Help to Better Direct Patients to Treatments?

Kaiser Foundation Health Plan of Washington^
| Washington
Dan Cherkin, PhD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Effectiveness of Nonsurgical Treatments for Lumbar Spinal Stenosis in Reducing Pain and Increasing Walking Ability

University of Pittsburgh
| Pennsylvania
Michael J. Schneider, DC, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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