Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Funding Opportunity Type
Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 23 of 23 results

Project Title
Project Status
Project Type

Rapid Reversal of Acute Suicidal Depression across the Lifespan: A Pragmatic Comparative Effectiveness Trial of Electroconvulsive Therapy vs. Intravenous Ketamine Treatment

Brigham and Women's Hospital
| Massachusetts
Amit Anand, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Individualizing Treatment for Asthma in Primary Care

DARTNet Institute
| Kansas
Wilson Pace, MD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Comparing Two Suicide Prevention Programs for Young People following an ER Visit

University of California, Los Angeles
| California
Joan Asarnow, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Preventing Suicide among Sexual and Gender Diverse Youth

University of Kentucky Research Foundation
| Kentucky
Elizabeth Arnold, PhD, MSW
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Prevent Suicide among Autistic Youth

The University of North Carolina at Chapel Hill
| North Carolina
Brenna Maddox, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Prevention Programs for Teens at Risk for Suicide

Kaiser Foundation Research Institute
| Oregon
Gregory Clarke, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research
Has Results

Comparing Two Ways to Provide Safety Planning Follow-Up Support for Adults and Teens at Risk of Suicide

St. Luke's Health System
| Idaho
Anna K. Radin, DrPH, MPH
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Stroke and Blood Clot Risk in Transgender Women Taking Hormones

Emory University
| Georgia
Michael Goodman, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Inpatient Versus Outpatient Settings for Treating Teens after a Suicidal Event

Cincinnati Children's Hospital Medical Center
| Ohio
Drew Barzman, MD
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Remote Cognitive Behavior Therapy for Major Depression in Primary Care

University of South Florida
| Florida
Robert Bossarte, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Depression Prevention Programs for Teens -- The Path 2 Purpose Study

University of Illinois at Chicago
| Illinois
Benjamin Van Voorhees, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Comparing the Safety and Effectiveness of Metformin with Other Medicines for Patients with Type 2 Diabetes and Chronic Kidney Disease

Joan and Sanford I. Weill Medical College of Cornell University
| New York
James Flory, MD, MSCE
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Two Programs for Managing Long-Term Health Problems for People with Lived Experience of Mental Illness

Dartmouth-Hitchcock Clinic
| New Hampshire
Sarah Pratt, PhD^
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Comparing a Multiple Sclerosis Fatigue Management Course Delivered via Teleconference, Internet, or in Person

Case Western Reserve University
| Ohio
Matthew A. Plow, PhD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Two Programs for Weight Loss among Marshallese Adults Living in the United States

University of Arkansas for Medical Sciences
| Arkansas
Pearl McElfish, PhD, MS, MBA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Increasing Patient Activation in American Indian Families with or at Risk for Chronic Kidney Disease

University of New Mexico Health Sciences Center
| New Mexico
Vallabh O. Shah, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Treatment Strategies to Prevent Future Blood Clots among Patients Who Received at Least Three Months of Blood Thinners -- The ALTERNATIVE Study

University of California, San Francisco
| California
Margaret Fang, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Methods to Identify and Predict Which Patients Will Have High Healthcare Needs and Use -- A PCORnet® Study

Cornell University
| New York
Rainu Kaushal, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Examining the Effectiveness of Case Management Programs on Preventing Hospital Stays in Older Adults with Multiple Chronic Health Problems -- A PCORnet® Study

University of Wisconsin-Madison
| Wisconsin
Maureen A. Smith, MD, PhD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Is Extra Time Planning for Care Associated with Improved Health among Patients with Type 2 Diabetes?

Tulane University
| Louisiana
Lizheng Shi, PhD, MA, MSPharm
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Assessing the Effects of Intensive Behavioral Therapy on Weight Loss among Patients with or at Risk for Type 2 Diabetes

Penn State Health Milton S. Hershey Medical Center
| Pennsylvania
Jennifer Kraschnewski, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Testing a Program to Improve the Integration of Behavioral Health Care into Primary Care Settings

University of Vermont and State Agriculture College
| Vermont
Benjamin Littenberg, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Ways to Manage Weight and Overall Health in Overweight and Obese Youth with Bipolar Spectrum Disorders Who Take Antipsychotic Medicines -- The MOBILITY Study

University of Cincinnati
| Ohio
Melissa P. DelBello, MD, MS
Project Status:
PCORI Peer-Review Process Complete
Project Type:
Research

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