Explore Our Portfolio
Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio |
Displaying 1 - 25 of 68 results
Project Title
Project Status
Project Type
Rapid Reversal of Acute Suicidal Depression across the Lifespan: A Pragmatic Comparative Effectiveness Trial of Electroconvulsive Therapy vs. Intravenous Ketamine Treatment
Brigham and Women's Hospital
| Massachusetts
Amit Anand, MD
Project Status:
In progress; Recruiting
Project Type:
Research
Sequential Multiple Assignment Randomized Trial for Bipolar Depression: SMART-BD
Massachusetts General Hospital
| Massachusetts
Andrew Nierenberg, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research
A TriaL ComparIng the EffectiVEness and ToleraBility of MEdicaTions in Older Adults with STablE Angina and Multiple ChRonic Conditions: LIVE BETTER
Yale University
| Connecticut
Michael Nanna, MD, MHS
Project Status:
In progress; Recruiting
Project Type:
Research
Comparing Two Ways to Help Patients Control High Blood Pressure
Brody School of Medicine at East Carolina University
| North Carolina
Doyle Cummings, PharmD
Project Status:
In progress; Recruiting
Project Type:
Research
Does Treating Genital Herpes in Pregnancy Reduce Racial Disparities in Severe Maternal Morbidity? -- The PCORI SMM Study
Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
De-Kun Li, MD, MPH, PHD
Project Status:
In progress; Recruiting
Project Type:
Research
Comparing Two Ways to Control Blood Pressure after Stroke
Wake Forest University Health Sciences
| North Carolina
Cheryl Bushnell, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®
Comparing Medicines to Treat Type 2 Diabetes among Patients with or at High Risk for Heart Disease -- The PRECIDENTD Study
Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Brendan Everett, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®
Comparing Two Prevention Programs for Teens at Risk for Suicide
Kaiser Foundation Research Institute
| Oregon
Gregory Clarke, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research
Comparing Two Ways to Reduce Flare-Ups among People with Inflammatory Bowel Disease -- The QUOTIENT Study
University of California San Diego
| California
Siddharth Singh, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research
Comparing How Well Different Diabetes Medicines Reduce the Risk of Heart Disease
Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
Romain Neugebauer, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research
Comparing Second-Line Medicines to Treat Type 2 Diabetes -- The BESTMED Study
Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Alexander Turchin, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®
Comparing Medicines to Treat Type 2 Diabetes among Patients Who Are at Risk for Heart Disease
Mayo Clinic
| Minnesota
Rozalina McCoy, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research
Has Results
Comparing the Effect of Four Diabetes Medicines on the Risk of Heart Disease among Patients with Type 2 Diabetes -- The CER-4-T2D Study
Brigham and Women's Hospital
| Massachusetts
Elisabetta Patorno, MD, DrPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Research
Comparing Two Ways to Treat Patients with Rheumatoid Arthritis -- The RA-PRO PRagmatic Trial (RA-PROPR)
The University of Alabama at Birmingham
| Alabama
Jasvinder Singh, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research
Comparing Two Ways to Offer Remote Therapy for Depressive Symptoms in People with Heart Disease
University of Kentucky
| Kentucky
Debra Moser, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research
Comparing Two Ways to Provide Follow-Up Care to Patients with Heart Failure after Hospital Discharge -- MIGHTY-Heart
The Trustees of Columbia University in the City of New York
| New York
Ruth Masterson Creber, PhD^
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®
Comparing Ways to Treat Anxiety in Youth
Children's Hospital Los Angeles
| California
Bradley S. Peterson, MD
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results
Self-Management in Older Adults with Chronic Heart Failure -- The iCOACH Study
University of Arkansas for Medical Sciences
| Arkansas
Judy Weber, PhD, RD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Comparing Two Treatments for Dental Cavities in Older Adults Living in Low-Income Housing
Case Western Reserve University
| Ohio
Suchitra Nelson, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research
Remote Cognitive Behavior Therapy for Major Depression in Primary Care
University of South Florida
| Florida
Robert Bossarte, PhD
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results
Comparing Two Treatments for Depression among Patients with Advanced Heart Failure
Cedars-Sinai Health System
| California
Waguih William IsHak, MD, FAPA
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Comparing Two Ways to Coordinate Care for Patients after Trauma
University of Washington
| Washington
Douglas Zatzick, MD
Project Status:
In progress; Data collected
Project Type:
Research
Has Results
Comparing Meditation versus Medicine for Patients with Anxiety Disorders
Georgetown University Medical Center
| District of Columbia
Elizabeth Hoge, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results
Understanding the Effect of Gender-Affirming Hormone Therapy on Sexual Health and Depression for Transgender Adults
Brigham and Women's Hospital
| Massachusetts
Sari L. Reisner, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Comparing Two Ways to Help Patients Manage Long-Term Non-Cancer Pain
RTI International
| North Carolina
Lauren A. McCormack, PhD, MSPH
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®