Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 75 results

Project Title
Project Status
Project Type

Putting Patient Decision Support in Place for Lung Cancer Screening through Tobacco Quitlines

The University of Texas MD Anderson Cancer Center
| Texas
Robert J. Volk, PhD
Project Status:
Completed
Project Type:
Implementation Project (Limited Competition D&I PFA)

Expanding the Use of IMPaCT: A Community Health Worker Program

University of Pennsylvania Perelman School of Medicine
| Pennsylvania
Shreya Kangovi, MD, MS
Project Status:
Completed
Project Type:
Implementation Project (Limited Competition D&I PFA)
Has Results

Comparing Two Ways to Help Sexual and Gender Minority Men Who Have Been Sexually Abused Reduce Depression and Increase Mental Health Treatment Engagement

Yale University
| Connecticut
Joan M. Cook, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Universal versus Focused Screening for Depression among Teens in High School -- The SHIELD Trial

Penn State Health Milton S. Hershey Medical Center
| Pennsylvania
Deepa L. Sekhar, MD, MSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Treatments for Depression among Patients with Advanced Heart Failure

Cedars-Sinai Health System
| California
Waguih William IsHak, MD, FAPA
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Does a Decision Aid Help Older Adults with Chronic Kidney Disease Choose Treatment? -- The DART Study

Trustees of Tufts College
| Massachusetts
Keren Ladin, PhD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Meditation versus Medicine for Patients with Anxiety Disorders

Georgetown University Medical Center
| District of Columbia
Elizabeth Hoge, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Understanding the Effect of Gender-Affirming Hormone Therapy on Sexual Health and Depression for Transgender Adults

Brigham and Women's Hospital
| Massachusetts
Sari L. Reisner, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Effectiveness of Three Treatments for Reducing Fatigue among Patients with Multiple Sclerosis -- The COMBO-MS Trial

University of Michigan
| Michigan
Tiffany J. Braley, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Two Approaches for Delivering Group Medical Visits for Patients with Diabetes

University of Colorado Denver
| Colorado
Bethany M. Kwan, PhD, MSPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Two Ways to Provide Advance Care Planning in Primary Care Clinics to Patients with a Serious Illness

Oregon Health & Science University
| Oregon
Annette M. Totten, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Identifying Barriers to Telehealth Home-Based Palliative Care for Patients with Serious Illness -- The HomePal Study

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
Huong Q. Nguyen, PhD, RN
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Two Medicines for Adults with Myasthenia Gravis -- The PROMISE-MG Study

Duke University
| North Carolina
Donald B. Sanders, MD, and Pushpa Narayanaswami, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Ways to Treat Depression among Pregnant Women and New Mothers with Low Incomes

Boston Medical Center
| Massachusetts
Michael Silverstein, MD, MPH; Caroline J Kistin, MD, MSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Identifying Challenges to Using Home-Based Palliative Care for Patients with Serious Illness

University of Southern California
| California
Susan Enguidanos, PhD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Testing Whether a Referral to a Telehealth Program Helps African-American and Hispanic Adults with COPD Transition from Hospital to Home

Feinstein Institute for Medical Research
| New York
Negin Hajizadeh, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Testing a Stepped-Care Program to Treat Emotional Distress among Patients with Lung or Head and Neck Cancer and Their Caregivers

University of Colorado Denver
| Colorado
Evelinn A. Borrayo, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Using Visual Analytic Methods to Identify Patient Groups

The University of Texas Medical Branch at Galveston
| Texas
Suresh K. Bhavnani, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Treatment Approaches for Older Adults with Treatment-Resistant Depression -- The OPTIMUM Study

Washington University School of Medicine
| Missouri
Eric J. Lenze, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Preferences for Depression and Diabetes Treatment among Adults of Different Racial and Ethnic Groups Who Reported Discrimination in Health Care

Cambridge Health Alliance
| Massachusetts
Benjamin Cook, PhD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Ways to Provide Care for Adults Who Experience Intimate Partner Violence and Depression

University of Rochester
| New York
Catherine Cerulli, JD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing a Self-Management Program with and without Peer Support to Improve Quality of Life for Patients with COPD

Johns Hopkins University
| Maryland
Hanan J. Aboumatar, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Testing the Effectiveness of Adding Group Therapy to Home Visiting Services on Reducing Postpartum Depression in Women with Low Incomes

Northwestern University
| Illinois
Darius Tandon, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Ways to Improve Depression Symptoms among Adults who Identify as LGBTQ+ -- The RADD Study

University of California, Los Angeles
| California
Bowen Chung, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Using Research Networks to Compare Medicines for Autoimmune and Inflammatory Diseases -- The Comparative Health Outcomes in Immune-mediated diseases CollaborativE (CHOICE) Study

University of Alabama at Birmingham
| Alabama
Jeffrey R. Curtis, MD, MPH, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®

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