Explore Our Portfolio
Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio |
Displaying 1 - 25 of 41 results
Project Title
Project Status
Project Type
Rapid Reversal of Acute Suicidal Depression across the Lifespan: A Pragmatic Comparative Effectiveness Trial of Electroconvulsive Therapy vs. Intravenous Ketamine Treatment
Brigham and Women's Hospital
| Massachusetts
Amit Anand, MD
Project Status:
In progress; Recruiting
Project Type:
Research
Sequential Multiple Assignment Randomized Trial for Bipolar Depression: SMART-BD
Massachusetts General Hospital
| Massachusetts
Andrew Nierenberg, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research
Comparing Two Ways to Screen People for Anxiety, Substance Use Disorders, and Intimate Partner Violence before and after Giving Birth -- The LTWP Study
Medical University of South Carolina
| South Carolina
Constance Guille, MD, MSCR
Project Status:
In progress; Recruiting
Project Type:
Research
Preventing Suicide among Sexual and Gender Diverse Youth
University of Kentucky Research Foundation
| Kentucky
Elizabeth Arnold, PhD, MSW
Project Status:
In progress; Recruiting
Project Type:
Research
Comparing Two Ways to Provide Palliative Care for Patients Who Are in the Hospital with Acute Myeloid Leukemia
Massachusetts General Hospital
| Massachusetts
Areej El-Jawahri, MD
Project Status:
In progress; Recruiting
Project Type:
Research
Comparing Medicines to Treat Type 2 Diabetes among Patients with or at High Risk for Heart Disease -- The PRECIDENTD Study
Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Brendan Everett, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®
Comparing Second-Line Medicines to Treat Type 2 Diabetes -- The BESTMED Study
Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Alexander Turchin, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®
Comparing Two Ways to Offer Remote Therapy for Depressive Symptoms in People with Heart Disease
University of Kentucky
| Kentucky
Debra Moser, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research
Comparing Two School Behavioral Health Programs to Improve Students' Academic Performance and Mental Health
University of South Carolina
| South Carolina
Mark Weist, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research
Expanding a Program to Help Clinics and Families Take Steps to Reduce Childhood Obesity
Massachusetts General Hospital
| Massachusetts
Elsie Taveras, MD, MPH
Project Status:
Completed
Project Type:
Implementation Project (Limited Competition D&I PFA)
Has Results
Does a Decision Aid Help Older Adults with Chronic Kidney Disease Choose Treatment? -- The DART Study
Trustees of Tufts College
| Massachusetts
Keren Ladin, PhD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results
Understanding the Effect of Gender-Affirming Hormone Therapy on Sexual Health and Depression for Transgender Adults
Brigham and Women's Hospital
| Massachusetts
Sari L. Reisner, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results
Developing New Methods for Comparing Treatments in Case-Control Studies
Harvard T.H. Chan School of Public Health
| Massachusetts
Goodarz Danaei, MD, MS, DSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results
Understanding How Patients' Response to Treatment Varies Using Predicted Risk
Tufts Medical Center, Inc.
| Massachusetts
David Kent, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results
Using Different Data Sets to Test How Well Clinical Prediction Models Work to Predict Patients' Risk of Heart Disease
Tufts Medical Center
| Massachusetts
David M. Kent, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results
Comparing Two Ways to Treat Depression among Pregnant Women and New Mothers with Low Incomes
Boston Medical Center
| Massachusetts
Michael Silverstein, MD, MPH; Caroline J Kistin, MD, MSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results
Comparing Three Treatments for Adults with Major Depression That Does Not Respond to First-Line Treatment -- The ASCERTAIN TRD Study
Massachusetts General Hospital
| Massachusetts
George Papakostas, MD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results
Comparing Preferences for Depression and Diabetes Treatment among Adults of Different Racial and Ethnic Groups Who Reported Discrimination in Health Care
Cambridge Health Alliance
| Massachusetts
Benjamin Cook, PhD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results
Comparing Three Ways to Increase Physical Activity in Patients with Depression and Cardiovascular Disease -- The Healthy Hearts Healthy Minds Study
Massachusetts General Hospital
| Massachusetts
Andrew A. Nierenberg, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Helping People with Serious Mental Illness Stop Smoking
Massachusetts General Hospital
| Massachusetts
Eden Evins, MD, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results
Comparing the Effects of Different Surgical Treatments on Quality of Life for Patients with Obesity
Massachusetts General Hospital
| Massachusetts
Matthew Hutter, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results
Methods to Apply Results from Randomized Trials to Patients in Clinical Practice
Harvard TH Chan School of Public Health
| Massachusetts
Issa J. Dahabreh, MD, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results
Matching Patients with Therapists to Improve Mental Health Care
University of Massachusetts Amherst
| Massachusetts
Michael J. Constantino, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results
Looking at the Effects of Antibiotic Use on Childhood Obesity and Growth -- The PCORnet® Antibiotics Study
Harvard Pilgrim Health Care, Inc.
| Massachusetts
Jason Block, MD, MPH^
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results
Testing an Online Program with and without Health Management Support to Help Patients Manage Their Weight
Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Heather J. Baer, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research