Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Funding Opportunity Type
Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 25 results

Project Title
Project Status
Project Type

Text-Messaging Telehealth and Contingency Management for Opioid Use Disorder Treatment Engagement

University of Pennsylvania
| Pennsylvania
Mucio Delgado, MD, MS
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Ways to Monitor Patients with Multiple Chronic Conditions after They Return Home from the Hospital for an Infection -- The ACCOMPLISH Study

UPMC Center for High ValueHealth Care
| Pennsylvania
Dr. Kalpana Char, MD*
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Surgical Treatments for Kidney Stones in Children and Youth

The Children's Hospital of Philadelphia
| Pennsylvania
Gregory E. Tasian, MD, MSc
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Four Ways to Treat Opioid Use Disorder

Philadelphia College of Osteopathic Medicine
| Pennsylvania
Michelle Lent
Project Status:
In progress; Recruiting
Project Type:
Research

Expanding the Use of IMPaCT: A Community Health Worker Program

University of Pennsylvania Perelman School of Medicine
| Pennsylvania
Shreya Kangovi, MD, MS
Project Status:
Completed
Project Type:
Implementation Project (Limited Competition D&I PFA)
Has Results

Comparing Universal versus Focused Screening for Depression among Teens in High School -- The SHIELD Trial

Penn State Health Milton S. Hershey Medical Center
| Pennsylvania
Deepa L. Sekhar, MD, MSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Using Two Versus Three Antibiotics to Treat MAC Lung Infections

Oregon Health & Science University
| Oregon
Kevin Winthrop, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Supporting Behavioral Health Home Approaches for Improving Patients’ Health and Wellness

UPMC Center for High ValueHealth Care
| Pennsylvania
James M. Schuster, MD, MBA
Project Status:
Completed
Project Type:
Implementation Project (Limited Competition D&I PFA)
Has Results

Comparing Ways to Help Primary Care Providers Prescribe Opioids Safely

University of Pittsburgh
| Pennsylvania
Kevin Kraemer, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Two Ways to Provide Advance Care Planning in Primary Care Clinics to Patients with a Serious Illness

Oregon Health & Science University
| Oregon
Annette M. Totten, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparing Two Ways to Offer Palliative Care to Improve Quality of Life for Patients with End-Stage Liver Disease

Thomas Jefferson University
| Pennsylvania
Victor J. Navarro, MD, BS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Help Patients Manage Multiple Chronic Conditions

UPMC Center for High ValueHealth Care
| Pennsylvania
Dan Swayze
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Programs to Treat Opioid Use Disorder in Primary Care and Substance Use Clinics

Public Health Management Corporation^
| Pennsylvania
David R. Gastfriend, MD
Project Status:
Terminated
Project Type:
Research
Has Results

Comparing Three Ways to Help Patients with Acute Pain Learn about Opioid Risks -- The Life STORRIED Study

University of Pennsylvania
| Pennsylvania
Zachary F. Meisel, MD, MPH, MSHP
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Treatment with Long-Term Steroids or Long-Term Antibiotics to Prevent Lung Infections in Patients with Bronchiectasis

Oregon Health & Science University
| Oregon
Kevin Winthrop, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Chemotherapy Recovery at Home versus in the Hospital for Children with Acute Myeloid Leukemia

The Children's Hospital of Philadelphia
| Pennsylvania
Richard Aplenc, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Helping People with Opioid Use Disorders Avoid Relapses after Leaving Jail

University of Pennsylvania
| Pennsylvania
George Woody, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Collaborative Goal Setting with or without Community Health Worker Support for Patients with Multiple Chronic Conditions

University of Pennsylvania
| Pennsylvania
Judith A. Long, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Three Ways to Improve Quality of Life for Patients with Kidney Disease and Their Caregivers

Pennsylvania State University Hershey Medical Center
| Pennsylvania
Nasrollah Ghahramani, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Using Graphic Novels when Choosing Treatment for Alcohol Use Disorder

Public Health Management Corporation^
| Pennsylvania
Adam Brooks, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Effect of Integrating Mental and Physical Health on Patients' Experiences of Care

Providence Health & Services
| Oregon
Bill Wright, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Broad- and Narrow-Spectrum Antibiotics for Children with Ear, Sinus, and Throat Infections

The Children's Hospital of Philadelphia
| Pennsylvania
Jeffrey Gerber, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Programs to Support Patients with Substance Use Disorders after They Leave the Hospital

Public Health Management Corporation
| Pennsylvania
Adam Brooks, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Testing Whether Home Visits by Community Health Workers Help African-American and Hispanic Patients with Low Incomes Better Manage Asthma

University of Pennsylvania
| Pennsylvania
Andrea J. Apter, MD, MA, MSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

For Children Discharged after Hospitalization for Serious Bacterial Infections, Are Orally Administered Antibiotics as Effective as Antibiotics Given Intravenously through a PICC?

The Children's Hospital of Philadelphia
| Pennsylvania
Ron Keren, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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