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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year the PCORI Board of Governors approved funding for the project or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 42 results

Project Title
Project Status
Project Type

Improved Statistical Methods for IV Designs in CER

The Trustees of The University of Pennsylvania
| Pennsylvania
Luke Keele, PhD
Project Status:
Awarded; Contract pending
Project Type:
Research
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Therapies for Improving Social and Thinking Skills in Patients with Schizophrenia

Beth Israel Deaconess Medical Center
| Massachusetts
Matcheri S. Keshavan, MD, and Russell K. Schutt, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research
Project Status:
In progress; Recruiting
Project Type:
Research

Developing Methods to Identify Patients Who Benefit Most from Different Treatments

University of Pennsylvania
| Pennsylvania
Yong Chen, PhD, MA
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Admit Children to Hospitals

Dartmouth-Hitchcock Clinic^
| New Hampshire
JoAnna Leyenaar, MD, MPH, MS
Project Status:
In progress; Recruiting
Project Type:
Research
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Programs to Treat Patients with Inflammatory Bowel Disease and Behavioral Health Conditions

UPMC Center for High-Value Health Care
| Pennsylvania
Eva Szigethy, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Radiation Treatments for Localized Prostate Cancer - COMPPARE

University of Florida Board of Trustees
| Florida
Nancy Mendenhall, MD
Project Status:
In progress; Recruiting
Project Type:
Research
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Approaches to Group Medical Visits for Patients with Diabetes

University of Colorado Denver
| Colorado
Bethany Matthews Kwan, PhD, MSPH
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Testing N-of-1 Trials for Research in Children with Inflammatory Bowel Disease and Adults with Atrial Fibrillation

Cincinnati Children’s Hospital Medical Center
| Ohio
Heather Kaplan, MD, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Developing and Testing New Methods for Estimating Treatment Effectiveness in Observational Studies Using High-Dimensional Data

Rutgers, The State University of New Jersey, New Brunswick
| New Jersey
Zhiqiang Tan, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Evaluating a Telehealth Program for Ostomy Self-Care among Cancer Survivors

The Trustees of the University of Pennsylvania^
| Pennsylvania
Robert S. Krouse, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Antibiotics and Surgery to Treat Appendicitis in Children

The Research Institute at Nationwide Children's Hospital
| Ohio
Peter C. Minneci, MD, MHSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Using Research Networks to Compare Medicines for Autoimmune and Inflammatory Diseases

University of Alabama at Birmingham
| Alabama
Jeffrey R. Curtis, MD, MPH, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Two Diets to Decrease Symptoms from Crohn's Disease -- The DINE-CD Study

Crohn's and Colitis Foundation of America, Inc.
| New York
James D. Lewis, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®

Helping People with Serious Mental Illness Stop Smoking

Massachusetts General Hospital
| Massachusetts
Eden Evins, MD, MPH
Project Status:
In progress; Data collected
Project Type:
Research
Project Status:
In progress; Recruitment not applicable
Project Type:
Research
Has Results

Matching Patients with Therapists to Improve Mental Health Care

University of Massachusetts Amherst
| Massachusetts
Michael J. Constantino, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Surgery versus Antibiotics to Treat Appendicitis -- The CODA Study

University of Washington
| Washington
David Reed Flum, MD, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Treatments for Children with Crohn's Disease -- The COMBINE Trial

The University of North Carolina at Chapel Hill
| North Carolina
Michael Kappelman, MD, MPH
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®

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