Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 23 of 23 results

Project Title
Project Status
Project Type

Text-Messaging Telehealth and Contingency Management for Opioid Use Disorder Treatment Engagement

University of Pennsylvania
| Pennsylvania
Mucio Delgado, MD, MS
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Ways to Screen People for Anxiety, Substance Use Disorders, and Intimate Partner Violence before and after Giving Birth -- The LTWP Study

Medical University of South Carolina
| South Carolina
Constance Guille, MD, MSCR
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Treat People with PTSD and Substance Use Disorder -- The COMPASS Study

Center for Veterans Research and Education
| Minnesota
Shannon M. Kehle-Forbes, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Three Ways to Start Taking Medicine for Opioid Use Disorder

University of Colorado Anschutz Medical Campus
| Colorado
Linda Zittleman, MPH, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Provide Pregnant Women with Prenatal Care and Treatment for Opioid Use Disorder

Yale University School of Medicine
| Connecticut
Ariadna Forray
Project Status:
In progress; Data collected
Project Type:
Research

Comparing Four Ways to Treat Opioid Use Disorder

Philadelphia College of Osteopathic Medicine
| Pennsylvania
Michelle Lent
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Comparing Two Ways to Help Patients with Sickle Cell Disease Manage Pain -- The CaRISMA Study

University of Pittsburgh
| Pennsylvania
Charles Jonassaint, PhD, MHS
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®

Remote Cognitive Behavior Therapy for Major Depression in Primary Care

University of South Florida
| Florida
Robert Bossarte, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Depression Prevention Programs for Teens -- The Path 2 Purpose Study

University of Illinois at Chicago
| Illinois
Benjamin Van Voorhees, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Methods to Deliver a Health Education Program for Pregnant Women Treated for Opioid Use Disorder in Rural Kentucky -- The PATH Home Trial

University of Kentucky Research Foundation
| Kentucky
Wendy Hansen, MD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Ways to Provide Treatment for Pregnant Women with Opioid Use Disorder

Trustees of Dartmouth College
| New Hampshire
Sarah Lord, PhD
Project Status:
In progress; Data collected
Project Type:
Research
Has Results

Comparing Two Programs for Managing Long-Term Health Problems for People with Lived Experience of Mental Illness

Dartmouth-Hitchcock Clinic
| New Hampshire
Sarah Pratt, PhD^
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Coordinate Care for Patients after Trauma

University of Washington
| Washington
Douglas Zatzick, MD
Project Status:
In progress; Data collected
Project Type:
Research
Has Results

Comparing Two Ways to Treat Youth with Anxiety or Obsessive-Compulsive Disorder (OCD)

Emma Pendleton Bradley Hospital
| Rhode Island
Jennifer Freeman, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Strategies for Health Clinics to Increase HPV Vaccinations in Youth

UCLA School of Public Health
| California
Roshan Bastani, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Help Patients Manage Long-Term Non-Cancer Pain

RTI International
| North Carolina
Lauren A. McCormack, PhD, MSPH
Project Status:
In progress; Enrollment complete
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Cognitive Behavioral Therapy with Peer-Led Support Groups for Patients with Chronic Pain Who Want to Reduce Opioid Use -- The EMPOWER Study

Stanford University School of Medicine
| California
Beth Darnall, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Community Health Worker and Mobile Health Programs to Help Young Adults with Sickle Cell Disease Transition to Using Adult Healthcare Services -- The COMETS Study

The Childrens' Hospital of Philadelphia
| Pennsylvania
Tanisha Belton, DrPh, MPH
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Transitional Care for Teens and Young Adults with Sickle Cell Disease with and without Peer Mentoring

Atrium Health
| North Carolina
Payal Desai
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Two Ways to Offer Palliative Care to Improve Quality of Life for Patients with End-Stage Liver Disease

Thomas Jefferson University
| Pennsylvania
Victor J. Navarro, MD, BS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Help Patients Manage Multiple Chronic Conditions

UPMC Center for High ValueHealth Care
| Pennsylvania
Dan Swayze
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Managing Long-Term Low Back Pain to Improve Health and Reduce Reliance on Opioid Medicines: Comparing Mindfulness Meditation and Cognitive Behavioral Therapy -- Strategies To Assist with Management of Pain (STAMP)

University of Wisconsin-Madison
| Wisconsin
Bruce Barrett
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Ways to Provide Hepatitis C Treatment for People Who Take Methadone

The Research Foundation for the State University of New York
| New York
Andrew Talal, MD, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

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