Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 31 results

Project Title
Project Status
Project Type

A TriaL ComparIng the EffectiVEness and ToleraBility of MEdicaTions in Older Adults with STablE Angina and Multiple ChRonic Conditions: LIVE BETTER

Yale University
| Connecticut
Michael Nanna, MD, MHS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Healthcare Visit Recording and Open Notes to Improve the Chronic Illness Care Experience for Older Adults (The CHRONICLE Trial)

Trustees of Dartmouth College
| New Hampshire
Paul Barr, PhD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Online Programs for Treating Chronic Pain -- The PROGRESS Study

Stanford University
| California
Beth Darnall, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Medicines to Treat Type 2 Diabetes among Patients with or at High Risk for Heart Disease -- The PRECIDENTD Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Brendan Everett, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing How Well Different Diabetes Medicines Reduce the Risk of Heart Disease

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
Romain Neugebauer, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Comparing Second-Line Medicines to Treat Type 2 Diabetes -- The BESTMED Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Alexander Turchin, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Medicines to Treat Type 2 Diabetes among Patients Who Are at Risk for Heart Disease

Mayo Clinic
| Minnesota
Rozalina McCoy, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research
Has Results

Comparing the Effect of Four Diabetes Medicines on the Risk of Heart Disease among Patients with Type 2 Diabetes -- The CER-4-T2D Study

Brigham and Women's Hospital
| Massachusetts
Elisabetta Patorno, MD, DrPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Comparing Two Ways to Prevent Severe Hypoglycemia in Patients with Type 2 Diabetes

Kaiser Foundation Health Plan of Washington
| Washington
James Ralston, MD, MPH
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Ways to Help Older Adults Living in Low-Income Housing Maintain Their Health and Independence -- The EPIC Study

Cedars-Sinai
| California
Harriet Aronow, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Approaches to Care Coordination for Patients with Multiple Health Needs

HealthPartners Institute
| Minnesota
Leif I. Solberg, MD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Ways to Reduce Medicine Use among Older Patients with Type 2 Diabetes

Kaiser Foundation Hospitals
| California
Richard W. Grant, MD, MPH
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Standard and Family Diabetes Self-Management Education for Improving Diabetes Outcomes

University of Arkansas for Medical Sciences
| Arkansas
Pearl A. McElfish, PhD, MBA
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Treatments for Dental Cavities in Older Adults Living in Low-Income Housing

Case Western Reserve University
| Ohio
Suchitra Nelson, PhD
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Comparing the Safety and Effectiveness of Metformin with Other Medicines for Patients with Type 2 Diabetes and Chronic Kidney Disease

Joan and Sanford I. Weill Medical College of Cornell University
| New York
James Flory, MD, MSCE
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Ways to Encourage and Improve End-of-Life Care Planning

Duke University
| North Carolina
Kimberly Johnson, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Help Patients Manage Multiple Chronic Conditions

UPMC Center for High ValueHealth Care
| Pennsylvania
Dan Swayze
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Two Programs for Weight Loss among Marshallese Adults Living in the United States

University of Arkansas for Medical Sciences
| Arkansas
Pearl McElfish, PhD, MS, MBA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Is Extra Time Planning for Care Associated with Improved Health among Patients with Type 2 Diabetes?

Tulane University
| Louisiana
Lizheng Shi, PhD, MA, MSPharm
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Assessing the Effects of Intensive Behavioral Therapy on Weight Loss among Patients with or at Risk for Type 2 Diabetes

Penn State Health Milton S. Hershey Medical Center
| Pennsylvania
Jennifer Kraschnewski, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Three Approaches to Improve Diabetes Self-Care among African-American Adults -- The MODEL Study

The University of Tennessee Health Science Center
| Tennessee
James E. Bailey, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Three Types of Weight Loss Surgery -- The PCORnet® Bariatric Study

Kaiser Permanente Washington Health Research Institute^
| Washington
David Arterburn, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Designing and Testing a Visit Planner to Help Patients Address Their Top Concerns during Healthcare Visits

Kaiser Foundation Research Institute
| California
Richard W. Grant, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Testing a Program with Nurse Coaching and Fitness-Tracking Devices to Help Patients Increase Confidence in Managing Diabetes

The Regents of the University of California, Davis
| California
Heather Margaret Young, MS, PhD, RN
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Using Home Coaching to Support Older Adults with Chronic Illness after an Emergency Room Visit

University of Florida
| Florida
Donna Lynne Carden, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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