Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 40 results

Project Title
Project Status
Project Type

Comparing Ways to Prevent Migraine in Youth

Cincinnati Children's Hospital
| Ohio
Scott Powers, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Efficacy of Pharmacologic Management of ADHD in Children and Youth with Autism Spectrum Disorder

The Research Institute at Nationwide Children's Hospital
| Ohio
Daniel Coury, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Prevention Programs for Teens at Risk for Suicide

Kaiser Foundation Research Institute
| Oregon
Gregory Clarke, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Two Treatments for Children with Lennox-Gastaut Syndrome

Ann & Robert H. Lurie Children's Hospital of Chicago
| Illinois
Sandi Lam, MD, MBA
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Three Ways to Treat Children with Inactive Spondyloarthritis -- The BACK-OFF JSpA Study

Children's Hospital of Philadelphia
| Pennsylvania
Pamela Weiss, MD, AB
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Improve Pre-Exposure Prophylaxis (PrEP) Use for HIV Prevention

Public Health Foundation Enterprises, Inc.
| California
Albert Liu, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Ways to Treat Anxiety in Youth

Children's Hospital Los Angeles
| California
Bradley S. Peterson, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Treat Anxiety Disorders among Children and Adolescents

Ann & Robert H. Lurie Children's Hospital of Chicago
| Illinois
John T. Walkup, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Provide Pregnant Women with Prenatal Care and Treatment for Opioid Use Disorder

Yale University School of Medicine
| Connecticut
Ariadna Forray
Project Status:
In progress; Data collected
Project Type:
Research
Has Results

Comparing Inpatient Versus Outpatient Settings for Treating Teens after a Suicidal Event

Cincinnati Children's Hospital Medical Center
| Ohio
Drew Barzman, MD
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Abatacept to Usual Care for Preventing Disease Worsening in Juvenile Idiopathic Arthritis

Duke University
| North Carolina
Laura Schanberg, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Methods to Deliver a Health Education Program for Pregnant Women Treated for Opioid Use Disorder in Rural Kentucky -- The PATH Home Trial

University of Kentucky Research Foundation
| Kentucky
Wendy Hansen, MD
Project Status:
In progress; Enrollment complete
Project Type:
Research

Comparing Two Ways to Provide Treatment for Pregnant Women with Opioid Use Disorder

Trustees of Dartmouth College
| New Hampshire
Sarah Lord, PhD
Project Status:
In progress; Data collected
Project Type:
Research
Has Results

Comparing Hair Removal Treatments for Adolescents and Young Adults with Pilonidal Disease

The Research Institute at Nationwide Children's Hospital
| Ohio
Peter C. Minneci, MD, MHSc
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparing Strategies for Health Clinics to Increase HPV Vaccinations in Youth

UCLA School of Public Health
| California
Roshan Bastani, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two School-Based Programs to Prevent Dental Cavities in Communities with Fewer Resources and Hispanic Communities

New York University College of Dentistry
| New York
Richard Niederman, DMD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Testing One State's Effort to Prevent Unsafe Treatments for Patients with Back Pain -- Back on Track

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| Washington
Lynn DeBar, PhD, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing the Effects of Acupressure on Cancer Treatment Side Effects in Children and Youth -- The ACT-CC Study

University of California San Francisco
| California
E. Anne Lown, DPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Treatments for Resistant Kawasaki Disease -- The KIDCARE Study

University of California San Diego
| California
Jane C. Burns, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Standard and Short Online Mindfulness Therapy Programs for Improving Well-Being -- The Healthy Mind Healthy You Study

Massachusetts General Hospital
| Massachusetts
Andrew A. Nierenberg, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Medicines for Long-Term Treatment of Bipolar Disorder

University of New Mexico Health Sciences Center
| New Mexico
Christophe G. Lambert, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Antibiotics and Surgery to Treat Appendicitis in Children

The Research Institute at Nationwide Children's Hospital
| Ohio
Peter C. Minneci, MD, MHSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Looking at the Effect of Treatment Duration for Newborn Infants Who Have Seizures

University of Michigan
| Michigan
Renée A. Shellhaas, MD, MS & Hannah C. Glass, MDCM, MAS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Three Ways to Start Treatment for Patients with Polyarticular Juvenile Idiopathic Arthritis -- The STOP-JIA Trial

Hackensack University Medical Center
| New Jersey
Yukiko Kimura, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Ways to Manage Weight and Overall Health in Overweight and Obese Youth with Bipolar Spectrum Disorders Who Take Antipsychotic Medicines -- The MOBILITY Study

University of Cincinnati
| Ohio
Melissa P. DelBello, MD, MS
Project Status:
PCORI Peer-Review Process Complete
Project Type:
Research

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