Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Funding Opportunity Type
Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 19 of 19 results

Project Title
Project Status
Project Type
Has Results

Understanding the Effect of Gender-Affirming Hormone Therapy on Sexual Health and Depression for Transgender Adults

Brigham and Women's Hospital
| Massachusetts
Sari L. Reisner, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Developing New Methods for Comparing Treatments in Case-Control Studies

Harvard T.H. Chan School of Public Health
| Massachusetts
Goodarz Danaei, MD, MS, DSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Understanding How Patients' Response to Treatment Varies Using Predicted Risk

Tufts Medical Center, Inc.
| Massachusetts
David Kent, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Linking Randomized Clinical Trials and ClaiTRD Data for Enhancing Randomized and Non-Randomized Patient-Centered Outcomes Evidence Generation

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Mehdi Najafzadeh, PhD, MA, TRD
Project Status:
Awarded; Contract not executed
Project Type:
Research
Has Results

Comparing the Benefits and Harms of Different Long-Term Treatments for Blood Clots -- The DARE Warfarin Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Katsiaryna Bykov, PharmD, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Standard and Short Online Mindfulness Therapy Programs for Improving Well-Being -- The Healthy Mind Healthy You Study

Massachusetts General Hospital
| Massachusetts
Andrew A. Nierenberg, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Ways to Decrease Severe Asthma Attacks among Black and Latinx Adults with Moderate to Severe Asthma -- The PREPARE Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Elliot Israel, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Patient-Centered Hepatitis C Virus Care for People Who Inject Drugs -- The HERO Study

Clemson University^
| South Carolina
Alain Litwin, MD, MPH, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Statistical Methods to Preserve Patient Privacy When Sharing and Analyzing Data

Harvard Pilgrim Health Care ,Inc.
| Massachusetts
Darren Toh, ScD, BPHAR, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Monitoring Oxygen Levels of Premature Babies at Home and in the Clinic -- The RHO Trial

University of Massachusetts Medical School^
| Massachusetts
Lawrence Rhein, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Statistical Models That Predict if Patients Will Take a New Medicine as Directed

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Joshua J. Gagne, TRD, PharmD, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Methods for Improving Confounding Control in Comparative Effectiveness Research Using Electronic Healthcare Databases

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Sebastian Schneeweiss, MD, MS, ScD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Determining the Best Methods for Using Patient Registry Data in Clinical Research

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Daniel H. Solomon, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does a Smartphone App Help Patients with Cancer Take Oral Chemotherapy as Planned?

Massachusetts General Hospital
| Massachusetts
Joseph A. Greer, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Including Patient Traits in Benchmarks for Diabetes Care

Harvard University School of Public Health
| Massachusetts
Marcia Anne Testa, BA, MPH, MPHIL, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Integrating Analytical Methods to Improve Comparative Effectiveness Research

Tufts Medical Center
| Massachusetts
John B. Wong, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Effects of a Stroke Medicine in Older Adults with and without Chronic Kidney Disease

University of South Carolina^
| South Carolina
John Brooks, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Methods for Variable Selection and Treatment Effect Estimation in Nonrandomized Studies with Few Outcome Events and Many Confounders

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Jessica M. Franklin, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing the Predicted Benefits and Harms of Using Adult versus Child Guidelines for Lipid Testing and Treatment in 17- to 21-Year-Olds

Tufts Medical Center, Inc.
| Massachusetts
Laurel K. Leslie, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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The Patient-Centered Outcomes Research Institute sends weekly emails about opportunities to apply for funding, newly funded research studies and engagement projects, results of our funded research, webinars, and other new information posted on our site.

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