Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 34 results

Project Title
Project Status
Project Type
Has Results

Comparing Messaging Systems to Increase Use of Online Programs That Help Smokers Quit -- Smoker-to-Smoker (S2S)

University of Massachusetts Medical School
| Massachusetts
Rajani Sadasivam, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Mobile Stroke Unit Treatment with Emergency Room Care among Patients Who Have Had a Stroke -- The BEST-MSU Study

Memorial Hermann-Texas Medical Center
| Texas
James Grotta, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing the Safety and Effectiveness of Different Medicines to Treat Multiple Sclerosis -- The COMBAT-MS Study

Karolinska Institute (Sweden)
| N/A
Fredrik Piehl, MD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Medicines to Help Patients with Multiple Sclerosis Feel Less Fatigued -- The TRIUMPHANT-MS Study

Johns Hopkins University^
| Maryland
Bardia Nourbakhsh, MD, MAS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Methods to Identify and Predict Which Patients Will Have High Healthcare Needs and Use -- A PCORnet® Study

Cornell University
| New York
Rainu Kaushal, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Examining the Effectiveness of Case Management Programs on Preventing Hospital Stays in Older Adults with Multiple Chronic Health Problems -- A PCORnet® Study

University of Wisconsin-Madison
| Wisconsin
Maureen A. Smith, MD, PhD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Two Physical Therapy Schedules for Children with Cerebral Palsy -- The ACHIEVE Study

The Ohio State University
| Ohio
Jill C. Heathcock, MPT, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Three Ways to Increase Colorectal Cancer Screening

Indiana University
| Indiana
Susan Rawl, PhD, MS, BSN
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Telehealth and Clinic-Based Care for Lowering Uncontrolled High Blood Pressure

HealthPartners Institute
| Minnesota
Karen L. Margolis, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Does a Web-Based Platform for Caregivers Help People with Down Syndrome Get Recommended Health Services?

Massachusetts General Hospital
| Massachusetts
Brian Skotko, MD, MPP
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Ways to Improve Depression Symptoms among Adults who Identify as LGBTQ+ -- The RADD Study

University of California, Los Angeles
| California
Bowen Chung, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®

Do Medicaid Health Homes Improve the Health of Adults with Diabetes?

Icahn School of Medicine at Mount Sinai
| New York
Victoria Mayer, MD, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Three Approaches to Improve Diabetes Self-Care among African-American Adults -- The MODEL Study

The University of Tennessee Health Science Center
| Tennessee
James E. Bailey, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Ways to Decrease Severe Asthma Attacks among Black and Latinx Adults with Moderate to Severe Asthma -- The PREPARE Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Elliot Israel, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Comparing Treatment Options for Women with Low-Risk Ductal Carcinoma In Situ (DCIS) -- The COMET Study

Alliance for Clinical Trials in Oncology Foundation
| Illinois
Shelley Hwang, MD, MPH
Project Status:
In progress; Enrollment complete
Project Type:
Research
Has Results

Helping Black Patients Decide on a Treatment for Chronic Heart Failure -- The VIVID Study

Duke University
| North Carolina
Kevin Lindsey Thomas, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Oral Medicines to Treat Hepatitis C Virus -- The PRIORITIZE Study

University of Florida
| Florida
David Robert Nelson, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Patient-Centered Hepatitis C Virus Care for People Who Inject Drugs -- The HERO Study

Clemson University^
| South Carolina
Alain Litwin, MD, MPH, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Testing a Program That Provides Care for Urgent Health Problems at Home Instead of the Emergency Room

Massachusetts General Hospital
| Massachusetts
Lisa I. Iezzoni, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Adding a Teachable Moment Approach to a Team-Based Primary Care Ask-Advise-Connect Approach for Tobacco Cessation

Oregon Health & Science University^
| Oregon
Susan (Sue) Flocke, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Stopping or Continuing Use of Disease Modifying Therapies in Older Adults with Multiple Sclerosis -- The DISCOMS Trial

University of Colorado Denver
| Colorado
John R. Corboy, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Ways to Reduce High Blood Pressure in Patients from Different Racial and Ethnic Groups -- The RICH LIFE Study

Johns Hopkins University
| Maryland
Lisa A. Cooper, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Approaches That Clinics Can Use to Help Control High Blood Pressure among Black Patients

The University of Alabama at Birmingham
| Alabama
Andrea L. Cherrington, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Three Types of Weight Loss Surgery -- The PCORnet® Bariatric Study

Kaiser Permanente Washington Health Research Institute^
| Washington
David Arterburn, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Medicines to Prevent Blood Clots in Patients Who Have Hip or Knee Replacement Surgery -- The PEPPER Study

Dartmouth-Hitchcock Clinic^
| New Hampshire
Vincent Domenic Pellegrini, MD
Project Status:
In progress; Recruiting
Project Type:
Research

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