Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 46 results

Project Title
Project Status
Project Type
Has Results

The HERO Research Program -- A PCORnet® Project to Support Studies on COVID-19

Duke University
| North Carolina
Adrian Hernandez, MD, MHS; Emily O'Brien, PhD (HERO registry); Susanna Naggie, MD (HERO-HCQ trial)
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Understanding the Culture of Learning Health Networks

University of Michigan
| Michigan
Alexandra Vinson, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Universal versus Focused Screening for Depression among Teens in High School -- The SHIELD Trial

Penn State Health Milton S. Hershey Medical Center
| Pennsylvania
Deepa L. Sekhar, MD, MSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Designing and Testing a Search Engine for Clinical Notes Included in Electronic Health Records

Nationwide Children's Hospital/The Ohio State University
| Ohio
Yungui Huang, PhD, MBA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Testing a Standard Approach to Match Patients with Addiction to Treatment Based on Their Needs -- The PCAST Study

RTI International
| North Carolina
Tami L. Mark, PhD, MBA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Ways to Treat Insomnia among Black Women

Boston University
| Massachusetts
Lynn Rosenberg, ScD, MS, and Eric Zhou, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Ways to Help Primary Care Providers Prescribe Opioids Safely

University of Pittsburgh
| Pennsylvania
Kevin Kraemer, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

A New Statistical Method for Designing Stepped-Wedge Cluster Trials

University of Texas Southwestern Medical Center at Dallas
| Texas
Song Zhang, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

New Methods to Improve Data Accuracy in Studies Using Electronic Health Record Data

Vanderbilt University Medical Center
| Tennessee
Bryan E. Shepherd, PhD; Pamela A. Shaw, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Two Programs to Maintain Weight Loss among Black Women with Obesity

University of Florida
| Florida
Carolyn M. Tucker, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Medicines for Adults with Myasthenia Gravis -- The PROMISE-MG Study

Duke University
| North Carolina
Donald B. Sanders, MD, and Pushpa Narayanaswami, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Ways to Treat Depression among Pregnant Women and New Mothers with Low Incomes

Boston Medical Center
| Massachusetts
Michael Silverstein, MD, MPH; Caroline J Kistin, MD, MSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Messaging Systems to Increase Use of Online Programs That Help Smokers Quit -- Smoker-to-Smoker (S2S)

University of Massachusetts Medical School
| Massachusetts
Rajani Sadasivam, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Identifying and Treating Childhood Hearing Loss in Rural Alaska -- The Hearing Norton Sound Study

Norton Sound Health Corporation
| Alaska
Samantha Kleindienst Robler, AuD, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Developing a New Method for Combining Data from Multiple Studies

Johns Hopkins University
| Maryland
Nilanjan Chatterjee, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Approaches to Help Patients and Doctors Talk about Chronic Pain Treatments -- Voices in Pain Care

Cedars-Sinai Medical Center
| California
Brennan Spiegel, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Programs to Help Families Living in Medically Underserved Areas Address Childhood Obesity

University of Virginia^
| Virginia
Paul Estabrooks, PhD, MS, and Jamie Zoellner, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Developing and Testing Software for Linking Patient Data from Multiple Sources

Texas A&M University Health Science Center
| Texas
Hye-Chung Kum, PhD, MSW, MS, FAMIA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Treatments for Resistant Kawasaki Disease -- The KIDCARE Study

University of California San Diego
| California
Jane C. Burns, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Understanding How to Use Single Patient Studies to Answer Patient-Identified Research Questions

Cincinnati Children’s Hospital Medical Center
| Ohio
Heather C. Kaplan, MD, MSCE; Lisa Opipari-Arrigan, PhD; Gregory M. Marcus, MD, MAS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Two Programs to Help Latino Patients from Low-Income Households Manage Their Diabetes

University of New Mexico Health Sciences Center
| New Mexico
Janet Page-Reeves, PhD, MA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Programs to Help Latino Men Lose Weight -- The HOMBRE Trial

Stanford University School of Medicine^
| California
Lisa G. Rosas, MPH, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Treatment Strategies to Prevent Future Blood Clots among Patients Who Received at Least Three Months of Blood Thinners -- The ALTERNATIVE Study

University of California, San Francisco
| California
Margaret Fang, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Standard and Short Online Mindfulness Therapy Programs for Improving Well-Being -- The Healthy Mind Healthy You Study

Massachusetts General Hospital
| Massachusetts
Andrew A. Nierenberg, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Improving Methods for Analyzing Data from Case-Only Studies

President & Fellows of Harvard College
| Massachusetts
Murray A. Mittleman, MD, DPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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