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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
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Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 210 results

Project Title
Project Status
Project Type

Comparing Cognitive-Behavioral Therapy versus Mindfulness-Based Therapy for Autistic Adults

The University of North Carolina at Chapel Hill
| North Carolina
Brenna Maddox, PhD
Project Status:
Awarded; Contract pending
Project Type:
Research

A Comparison of Two School-Based Interventions to Manage Anxiety in Autistic Students

University of Colorado Denver
| Colorado
Judy Reaven, PhD
Project Status:
Awarded; Contract pending
Project Type:
Research

Optimizing the Outcomes of Adults with Gram-Negative Bloodstream Infections

Johns Hopkins University School of Medicine
| Maryland
Pranita Tamma, MD, MHS
Project Status:
Awarded; Contract pending
Project Type:
Research

Comparative Effectiveness of an Individualized Model of Hemodialysis versus Conventional Hemodialysis

Wake Forest University Health Sciences
| North Carolina
Mariana Murea, MD
Project Status:
Awarded; Contract pending
Project Type:
Research

Nasal Steroids, Irrigation, Oral Antibiotics, and Subgroup Targeting for Effective Management of Sinusitis

Georgetown University Medical Center
| District of Columbia
Daniel Merenstein, MD
Project Status:
Awarded; Contract pending
Project Type:
Research

Cardiac Resynchronization Therapy Using His/Left Bundle Pacing vs. Left Ventricular Epicardial Pacing in Patients with Heart Failure

Baylor College of Medicine
| Texas
Mihail G. Chelu, MD, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Rapid Reversal of Acute Suicidal Depression across the Lifespan: A Pragmatic Comparative Effectiveness Trial of Electroconvulsive Therapy vs. Intravenous Ketamine Treatment

Brigham and Womens Hospital, Boston
| Massachusetts
Amit Anand, MD
Project Status:
Awarded; Contract pending
Project Type:
Research

Sequential Multiple Assignment Randomized Trial for Bipolar Depression: SMART-BD

Massachusetts General Hospital
| Massachusetts
Andrew Nierenberg, MD
Project Status:
Awarded; Contract pending
Project Type:
Research

A TriaL ComparIng the EffectiVEness and ToleraBility of MEdicaTions in Older Adults with STablE Angina and Multiple ChRonic Conditions: LIVE BETTER

Yale University
| Connecticut
Michael Nanna, MD, MHS
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Stent Omission after Ureteroscopy and Lithotripsy in the Michigan Urological Surgery Improvement Collaborative (SOUL MUSIC)

University of Michigan Medical School, Department
| Michigan
Khurshid Ghani, MS
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Preventing Suicidal Behavior with Diverse High-Risk Youth in Acute Care Settings

Johns Hopkins University
| Maryland
Holly Wilcox, PhD, MA
Project Status:
Awarded; Contract pending
Project Type:
Research

COOL PRIME: Cooling Mild HIE Parental Selection of Outcomes

UT Southwestern Medical Center
| Texas
Lina Chalak, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

LIVE-SMART: Liver cirrhosis interventions for fall prevention: a sequential, multiple assignment randomized trial

University of Michigan
| Michigan
Elliot Tapper, MD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Individualizing Treatment for Asthma in Primary Care

American Academy of Family Physicians
| Kansas
Wilson Pace, MD
Project Status:
Awarded; Contract pending
Project Type:
Research

CBT via Telehealth + Amitriptyline Compared to CBT via Telehealth: Pediatric Migraine Prevention

Cincinnati Children's Hospital
| Ohio
Scott Powers, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Expanding First-Line Options for Depression & Matching Treatments: Hatha Yoga vs. Behavioral Therapy

Massachusetts General Hospital
| Massachusetts
Louisa Sylvia, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Comparing Analgesic Regimen Effectiveness and Safety After Surgery – The CARES Trial

University of Michigan
| Michigan
Mark Bicket MD, PHD
Project Status:
In progress; Not yet recruiting
Project Type:
Research

Colonoscopy vs. Stool-Based Testing for Older Adults With a History of Colon Polyps

Dartmouth-Hitchcock Clinic
| New Hampshire
Audrey Calderwood, MD, MS
Project Status:
In progress; Not yet recruiting
Project Type:
Research

THRIVE: Trajectories of Recovery after Intravenous Propofol vs inhaled VolatilE anesthesia

Regents of the University of Michigan
| Michigan
Sachin Kheterpal, MD, MBA
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Medicines to Treat Type 2 Diabetes among Patients with or at High Risk for Heart Disease -- The PRECIDENTD Study

Brigham and Women's Hospital
| Massachusetts
Brendan Everett, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Treatments to Help Cancer Survivors with Anxiety -- The MELODY Study

Memorial Sloan Kettering Cancer Center
| New York
Jun Mao, MD, MSCE
Project Status:
In progress; Recruiting
Project Type:
Research

Treat-to-Target of Endoscopic Remission in Patients with Inflammatory Bowel Diseases in Symptomatic Remission: A Pragmatic Randomized Controlled Trial

University of California San Diego
| California
Siddharth Singh, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Ways to Monitor and Treat High Blood Pressure in Children with Chronic Kidney Disease -- The PRESERVE Study

Children's Hospital of Philadelphia
| Pennsylvania
Christopher Forrest, MD, PhD
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparative Effectiveness of Palliative Surgery versus Additional Anti-Seizure Medications for Lennox-Gastaut Syndrome

Ann & Robert H. Lurie Children's Hospital of Chicago
| Illinois
Sandi Lam
Project Status:
In progress; Not yet recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing the Effects of Different Treatment Approaches for Neuroendocrine Tumors on Patient-Reported Outcomes -- The NET-PRO Study

University of Iowa
| Iowa
Michael O'Rorke, PhD, BSc
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

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