Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 107 results

Project Title
Project Status
Project Type

Comparing How State and Local COVID-19 Policies Affect Patient-Reported Outcomes

The Regents of the University of California, San Francisco
| California
Mark Pletcher, MD, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®

Comparative Effectiveness of Single-Site and Scattered-Site Permanent Supportive Housing on Patient-Centered and COVID-19 Related Outcomes for People Experiencing Homelessness

University of Southern California
| California
Benjamin Henwood, PhD, MA, MSW
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Developing Methods for Combining and Analyzing Electronic Health Record Data

University of Pennsylvania
| Pennsylvania
Yong Chen, PhD, MA
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®

Comparative Effectiveness Trial of Perioperative Telemonitoring for Functional Recovery and Symptoms

City of Hope
| California
Virginia Sun, PhD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Improving Family-Centered Pediatric Trauma Care -- The Standard of Care versus the Virtual Pediatric Trauma Center

The Regents of the University of California, Davis
| California
James P. Marcin, MD, MPH
Project Status:
In progress; Data collected
Project Type:
Research

Comparing Two Programs for Managing Hearing Loss among Older Adults in Assisted Living Facilities

University of Pittsburgh
| Pennsylvania
Catherine Palmer, PhD
Project Status:
In progress; Data collected
Project Type:
Research

Developing Methods to Identify Patients Who Benefit Most from Different Treatments

University of Pennsylvania
| Pennsylvania
Yong Chen, PhD, MA
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Two Ways to Help Patients with Sickle Cell Disease Manage Pain -- The CaRISMA Study

University of Pittsburgh
| Pennsylvania
Charles Jonassaint, PhD, MHS
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Increase HPV Testing for Cervical Cancer Screening

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
Chun Chao, PhD, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Two Ways to Perform Catheter Ablation to Treat Abnormal Heart Rhythms

The Regents of the University of California, San Francisco
| California
Gregory Marcus, MD, MAS
Project Status:
In progress; Data collected
Project Type:
Research
Has Results

Comparing Universal versus Focused Screening for Depression among Teens in High School -- The SHIELD Trial

Penn State Health Milton S. Hershey Medical Center
| Pennsylvania
Deepa L. Sekhar, MD, MSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Ways for Patients, Doctors, and Clinics to Improve Blood Pressure Control -- A PCORnet® Study

University of California San Francisco
| California
Mark J. Pletcher, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Evaluating the Safety of Direct-Acting Antivirals for Treating Hepatitis C

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
Elizabeth McGlynn, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Home- Versus Clinic-Based Phototherapy for the Treatment of Psoriasis -- The LITE Study

University of Pennsylvania
| Pennsylvania
Joel Mitchell Gelfand, MD, MS
Project Status:
In progress; Data collected
Project Type:
Research
Has Results

Comparing Ways to Help Primary Care Providers Prescribe Opioids Safely

University of Pittsburgh
| Pennsylvania
Kevin Kraemer, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Approaches to Advance Care Planning for Patients with Advanced Illness

Regents of the University of California, Los Angeles
| California
Neil S. Wenger MD, MPH
Project Status:
In progress; Data collected
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Identifying Barriers to Telehealth Home-Based Palliative Care for Patients with Serious Illness -- The HomePal Study

Kaiser Foundation Research Institute, a Division of Kaiser Foundation Hospitals
| California
Huong Q. Nguyen, PhD, RN
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing the Effect of Adding Acupuncture and Pain Counseling to Usual Care on Reducing Pain among Patients with Cancer -- The PRACXIS Study

University of California, San Francisco
| California
Maria Chao, DrPH, MPA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Three Ways to Help Patients Manage Multiple Chronic Conditions

UPMC Center for High ValueHealth Care
| Pennsylvania
Dan Swayze
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Two Ways to Decrease Medicine Use for Nursing Home Residents with Dementia

University of Pittsburgh^
| Pennsylvania
Natalie E. Leland, PhD
Project Status:
PCORI Peer-Review Process Complete
Project Type:
Research
Has Results

Comparing the Effects of Acupressure on Cancer Treatment Side Effects in Children and Youth -- The ACT-CC Study

University of California San Francisco
| California
E. Anne Lown, DPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Approaches to Help Patients and Doctors Talk about Chronic Pain Treatments -- Voices in Pain Care

Cedars-Sinai Medical Center
| California
Brennan Spiegel, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Treatments for Resistant Kawasaki Disease -- The KIDCARE Study

University of California San Diego
| California
Jane C. Burns, MD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Identifying Challenges to Using Home-Based Palliative Care for Patients with Serious Illness

University of Southern California
| California
Susan Enguidanos, PhD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Three Ways to Help Patients with Acute Pain Learn about Opioid Risks -- The Life STORRIED Study

University of Pennsylvania
| Pennsylvania
Zachary F. Meisel, MD, MPH, MSHP
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

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