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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
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Displaying 1 - 25 of 459 results

Project Title
Project Status
Project Type

Best Practices to Prevent COVID-19 Illness in Staff and People with Serious Mental Illness and Developmental Disabilities in Congregate Living Settings

Massachusetts General Hospital (The General Hospital Corp.)
| Massachusetts
Stephen Bartels, MD, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Does Staff Training and Support for Using Infection Control Practices Prevent the Spread of COVID-19 in Nursing Homes?

Pennsylvania State University, Hershey Medical Center
| Pennsylvania
Jennifer Kraschnewski, MD, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Does the Stress First Aid Program Improve Well-Being among Healthcare Workers during the COVID-19 Pandemic? -- The COVER-HCW Project

RAND Corporation
| California
Lisa S. Meredith, PhD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Ways to Monitor Patients with COVID-19 at Home -- COVID Watch

University of Pennsylvania Perelman School of Medicine
| Pennsylvania
Mucio Delgado, MD, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

The HERO Research Program -- A PCORnet® Project to Support Studies on COVID-19

Duke University
| North Carolina
Adrian Hernandez, MD, MHS; Emily O'Brien, PhD (HERO registry); Susanna Naggie, MD (HERO-HCQ trial)
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Evaluating Therapies to Prevent Future Stroke in Patients with Patent Foramen Ovale-Related Strokes -- The SCOPE Study

Tufts Medical Center Inc.
| Massachusetts
David M. Kent, MD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Improving Methods for Addressing Post-Randomization Selection Bias in Cluster Randomized Trials

Duke University
| North Carolina
Fan Li, PhD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Developing Methods for Conducting Incomplete Stepped-Wedge Cluster Randomized Trials

University of North Carolina at Chapel Hill
| North Carolina
John S. Preisser, PhD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Self-Management in Older Adults with Chronic Heart Failure -- The iCOACH Study

University of Arkansas for Medical Sciences
| Arkansas
Judy Weber, PhD, RD
Project Status:
PCORI Peer-Review Process Complete
Project Type:
Research

Comparing Non-Medicine Pain Management Therapies for Adults with Advanced Cancer -- The IMPACT Trial

Memorial Sloan Kettering
| New York
Jun Mao, MD, MSCE
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Developing Methods for Comparing Outcomes Across Patient Groups in Observational Studies

Duke University School of Medicine
| North Carolina
Laine Thomas, PhD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

A New Method to Create Personalized Treatment Guidance Using Patient Health Data

University of Wisconsin School of Medicine and Public Health
| Wisconsin
Guanhua Chen, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Stroke and Blood Clot Risk in Transgender Women Taking Hormones

Emory University
| Georgia
Michael Goodman, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Understanding the Culture of Learning Health Networks

University of Michigan
| Michigan
Alexandra Vinson, PhD
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research Infrastructure

Developing Methods to Capture Information from Electronic Health Records on Whether Patients Take Medicine as Directed

The University of Texas Health Science Center at Houston
| Texas
Kirk Roberts, PhD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®

Methods to Help Link and Analyze Data from Multiple Data Sources

Brown University School of Public Health
| Rhode Island
Roee Gutman, PhD, MS, BSc
Project Status:
PCORI Peer-Review Process Complete
Project Type:
Research
Has Results

Developing and Testing a New Method for Comparing More than Two Treatments Using Electronic Health Records

Rutgers, The State University of New Jersey
| New Jersey
Liangyuan Hu, PhD
Project Status:
PCORI Peer-Review Process Complete
Project Type:
Research
Has Results

Comparing Universal versus Focused Screening for Depression among Teens in High School -- The SHIELD Trial

Penn State Health Milton S. Hershey Medical Center
| Pennsylvania
Deepa L. Sekhar, MD, MSc
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research

Comparing Two State Insurer Strategies to Prevent Unsafe Opioid Prescribing

University of Washington
| Washington
Gary Franklin, MD, MPH
Project Status:
PCORI Peer-Review Process Complete
Project Type:
Research

Comparing Behavioral Activation and Medicine Management for Treating Depression in Patients with Advanced Heart Failure

Cedars-Sinai Health System
| California
Waguih Ishak, MD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Ways for Patients, Doctors, and Clinics to Improve Blood Pressure Control -- A PCORnet® Study

University of California San Francisco
| California
Mark J. Pletcher, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing Treatments for Patients with Inflammatory Bowel Disease Who Don't Respond to Anti-TNF Therapy

The University of North Carolina at Chapel Hill^
| North Carolina
Michael Kappelman, MD, MPH^
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Designing and Testing a Search Engine for Clinical Notes Included in Electronic Health Records

Nationwide Children's Hospital/The Ohio State University
| Ohio
Yungui Huang, PhD, MBA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Testing a Standard Approach to Match Patients with Addiction to Treatment Based on Their Needs -- The PCAST Study

RTI International
| North Carolina
Tami L. Mark, PhD, MBA
Project Status:
Completed; PCORI Public and Professional Abstracts, and Final Research Report Posted
Project Type:
Research
Has Results

Comparing Two Ways to Help Patients with Chronic Kidney Disease and Their Care Partners Choose among Treatment Options -- The DART Study

Tufts University
| Massachusetts
Keren Ladin, PhD, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

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