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State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
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Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 10 of 10 results

Project Title
Project Status
Project Type

Comparing Medicines for Treating Type 2 Diabetes among Patients with Chronic Kidney Disease

Joan and Sanford I. Weill Medical College of Cornell University
| New York
Alvin Mushlin, MD, ScM
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Behavioral Activation and Medicine Management for Treating Depression in Patients with Advanced Heart Failure

Cedars-Sinai Health System
| California
Waguih Ishak, MD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Can Early Tracheostomy Improve Recovery and Survival in Patients with Severe Stroke and Breathing Failure? -- The SETPOINT 2 Study

Maine Medical Center
| Maine
David Seder, MD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Three Treatments for Adults with Major Depression That Does Not Respond to First-Line Treatment -- The ASCERTAIN TRD Study

Massachusetts General Hospital
| Massachusetts
George Papakostas, MD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Treatments for Older Adults Who Have Major Depression That Does Not Respond to First-Line Antidepressant Medicines -- The OPTIMUM Study

Washington University School of Medicine
| Missouri
Eric Juckeland Lenze, MD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Safety and Effectiveness of Medicines Patients Take for Many Years to Treat Multiple Sclerosis (MS) -- The COMBAT-MS Study

Karolinska Institute (Sweden)
Fredrik Piehl, MD, PhD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

The Role of Breast Density in Decision Making for Breast Cancer Screening and Diagnostic Testing -- The BCSC-ADVANCE Study

University of California, Davis
| California
Diana Miglioretti, PhD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Two Types of Surgery for Young Patients with Chiari Type I Malformation and Syringomyelia

Washington University School of Medicine
| Missouri
David Limbrick, MD, MS, PhD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Can People in Later Stages of MS Stop Taking Disease-Modifying Therapies? (The DISCOMS Trial)

University of Colorado Denver
| Colorado
John Corboy, MD, MA
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Options for Treating Uterine Fibroids through a Patient Information Registry -- The COMPARE-UF Study

Duke University
| North Carolina
Evan R. Myers, MD, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

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