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State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
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Year Awarded Year Awarded The year the PCORI Board of Governors approved funding for the project or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 36 results

Project Title
Project Status
Project Type

A Real-World Comparative Effectiveness Trial of Treatment Strategies in Patients with Rheumatoid Arthritis -- The RA-PRO PRagmatic Trial (RA-PROPR)

University of Alabama at Birmingham
| Alabama
Jasvinder Singh, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

A Comparison of Prolonged Exposure Therapy, Pharmacotherapy, and Their Combination for PTSD: What Works Best and For Whom

University of Pennsylvania Perelman School of Medicine
| Pennsylvania
Keith Bredemeier, PhD, BA
Project Status:
In progress; Recruiting
Project Type:
Research

Does the Stress First Aid Program Improve Well-Being among Healthcare Workers during the COVID-19 Pandemic? -- The COVER-HCW Project

RAND Corporation
| California
Lisa S. Meredith, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Treat Anxiety in Patients Who Go to the Emergency Room with Low-Risk Chest Pain

Trustees of Indiana University
| Indiana
Paul Musey, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Types of Prostate Biopsy

Weill Cornell Medicine
| New York
Jim C. Hu, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Are Two Hearing Aids Better Than One for Age-Related Hearing Loss?

Duke University
| North Carolina
Sherri L. Smith, AuD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Ways to Treat People with PTSD and Substance Use Disorder -- The COMPASS Study

Center for Veterans Research and Education
| Minnesota
Shannon M. Kehle-Forbes, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Programs for Managing Hearing Loss among Older Adults in Assisted Living Facilities

University of Pittsburgh
| Pennsylvania
Catherine Palmer, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Ways to Treat Anxiety in Youth

Children's Hospital Los Angeles
| California
Bradley S. Peterson, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Five Treatment Approaches for Men with Prostate Cancer -- The PC CONCEPT Study

Joan & Sanford I. Weill Medical College of Cornell University
| New York
Jim C. Hu, MD, MPH, and Ronald C. Chen, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Treat Anxiety Disorders among Children and Adolescents

Ann & Robert H. Lurie Children's Hospital of Chicago
| Illinois
John T. Walkup, MD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Ways to Obtain Hearing Aids for People with Age-Related Hearing Loss

Northwestern University
| Illinois
Sumitrajit Dhar, PhD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Primary Care Treatment Options for People with PTSD

University of Washington
| Washington
John Fortney, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Types of Well-Child Visits for Preventing Obesity among Preschool-Aged Children in Rural Areas

Geisinger Clinic
| Pennsylvania
Lisa Bailey-Davis, RD, DEd
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Manage Pain after High-Dose Chemotherapy

Memorial Sloan-Kettering Cancer Center
| New York
Gary Deng, MD, PhD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Three Surgical Treatments for Kidney Stones in Children and Youth

The Children's Hospital of Philadelphia
| Pennsylvania
Gregory E. Tasian, MD, MSc
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Non-Medicine Pain Management Therapies for Adults with Advanced Cancer -- The IMPACT Trial

Memorial Sloan Kettering
| New York
Jun Mao, MD, MSCE
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Two Ways to Help Patients with Sickle Cell Disease Manage Pain -- CaRISMA

University of Pittsburgh
| Pennsylvania
Charles Jonassaint, PhD, MHS
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Two Treatment Options for Recurrent Bladder Cancer

University of Washington Office of Sponsored Programs, Department of Urology
| Washington
John Gore, MD, MS
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Online and In-Person Cognitive Behavioral Therapy in Youth with Anxiety Disorders -- The Kids FACE FEARS Study

Boston Medical Center Corporation
| Massachusetts
Donna Pincus
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing Treatments for Chronic Low Back Pain

University of Utah
| Utah
Julie Fritz, PhD
Project Status:
In progress; Recruiting
Project Type:
Research, Research Conducted Using PCORnet®

Using Two Versus Three Antibiotics to Treat MAC Lung Infections

Oregon Health & Science University
| Oregon
Kevin Winthrop, MD, MPH
Project Status:
In progress; Recruiting
Project Type:
Research
Has Results

Comparing Treatments for Resistant Kawasaki Disease -- The KIDCARE Study

University of California San Diego
| California
Jane Burns, MD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing Medicines that Prevent Blood Clots for Emergency Room Patients with Serious Fractures -- The PREVENT CLOT Study

University of Maryland Baltimore
| Maryland
Robert O'Toole, MD, TRD
Project Status:
In progress; Recruiting
Project Type:
Research

Comparing the Benefits and Harms of Medicines for Long-Term Treatment of Blood Clots -- The ALTERNATIVE Study

University of California, San Francisco
| California
Margaret Fang, MD, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

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