Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
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Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 25 of 41 results

Project Title
Project Status
Project Type

A Randomized Controlled Trial to Evaluate a Trauma-Informed Partner Violence Intervention Program

Trustees of Boston University, BUMC
| Massachusetts
Casey Taft, Ph.D.
Project Status:
Awarded; Contract pending
Project Type:
Research

The SCOPE Trial: Sleep, Cognition, and Pain Bundle Versus Enhanced Recovery After Surgery-Cardiac for Postoperative Delirium

Beth Israel Deaconess Medical Center
| Massachusetts
Balachundhar Subramaniam, M.D., MPH
Project Status:
Awarded; Contract pending
Project Type:
Research

Patient-Level Artificial Intelligence to Derive Longitudinal Phenotypes for Comparative Clinical Effectiveness Research

Dana-Farber Cancer Institute
| Massachusetts
Kenneth Kehl, M.D., MPH
Project Status:
Awarded; Contract pending
Project Type:
Research

Pathways to Perinatal Mental Health Equity (Pathways)

UMass Chan Medical School
| Massachusetts
Nancy Byatt, B.A., D.O., MBA, M.S.
Project Status:
Awarded; Contract pending
Project Type:
Research

Preoperative Fasting Versus Not Fasting in Critically Ill Patients

Massachusetts General Hospital/Harvard Medical School
| Massachusetts
Alexander Nagrebetsky, M.D., M.S.
Project Status:
Awarded; Contract pending
Project Type:
Research

Promoting Shared Decision Making About Colorectal Cancer Testing in Older Adults

The General Hospital Coporation d/b/a Massachusetts General Hospital
| Massachusetts
Karen Sepucha, Ph.D.
Project Status:
Awarded; Contract pending
Project Type:
Implementation Project (Implementation of Effective Shared Decision Making Approaches PFA)

Effectiveness of Brief Intervention in Primary Care for Diverse Young People

RAND Corporation
| Massachusetts
Elizabeth D'Amico, Ph.D.
Project Status:
Awarded; Contract pending
Project Type:
Research

Home-Based Pulmonary Rehabilitation With Health Coaching in Patients With Fibrotic Lung Disease

Mayo Clinic Rochester
| Minnesota
Teng Moua, M.D.
Project Status:
Awarded; Contract pending
Project Type:
Research

Comparative Effectiveness of Lifestyle Interventions for Older Cancer Survivors and Their Caregivers

Dana-Farber Cancer Institute
| Massachusetts
Christina Dieli-Conwright, Ph.D.
Project Status:
Awarded; Contract pending
Project Type:
Research

Measurement Matters: Refining and Validating a Patient-Centered Outcomes Research Engagement Measure

University of Massachusetts Boston
| Massachusetts
Marc Cohen, Ph.D., M.A.
Project Status:
Awarded; Contract pending
Project Type:
Research, Research Conducted Using PCORnet®

Effectiveness of a Multimodal Intervention for Transitions of Care after Lower Limb Fracture

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Patricia Dykes, PhD, RN, MA
Project Status:
Awarded; Contract pending
Project Type:
Research

Best Practices to Prevent COVID-19 Illness in Staff and People with Serious Mental Illness and Developmental Disabilities in Congregate Living Settings

Massachusetts General Hospital (The General Hospital Corp.)
| Massachusetts
Stephen Bartels, MD, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Toward a New Generation of Matching Methods for Comparative Effectiveness Research

Harvard Medical School
| Massachusetts
Jose R. Zubizarreta, PhD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Developing Methods to Improve the Accuracy of Data Obtained from Clinicians' Notes in Electronic Health Records

Brigham and Women's Hospital
| Massachusetts
Alexander Turchin, MD, MS
Project Status:
In PCORI Peer-Review Process
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Using PCORnet to Monitor Provider and Patient Risk Factors Related to the Opioid Epidemic

REACHnet CDRN
| Louisiana
Kristin Lyman, JD, MHA
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research Infrastructure
Has Results

Does a Decision Aid Help Older Adults with Chronic Kidney Disease Choose Treatment? -- The DART Study

Trustees of Tufts College
| Massachusetts
Keren Ladin, PhD, MS
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Ways to Train Healthcare Clinic Staff to Ask Patients about Sexual Orientation and Gender Identity

Fenway Community Health Center
| Massachusetts
Kenneth H. Mayer, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Using PCORnet to Improve Data Quality and Patient Follow-Up Within the Transcatheter Valve Therapy Registry

Mayo Clinic
| Minnesota
Maurice E. Sarano, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research, Research Conducted Using PCORnet®

Comparing Approaches to Improve Black Patients’ Chances of Getting Live Donor Kidney Transplants

Beth Israel Deaconess Medical Center, Inc
| Massachusetts
James R. Rodrigue, PhD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Comparing the Effects of Three-Week versus Five-Week Courses of Radiation Therapy for Women with Breast Cancer Getting Mastectomy with Breast Reconstruction

Dana-Farber Cancer Institute
| Massachusetts
Rinaa Sujata Punglia, MD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

Linking Randomized Clinical Trials and ClaiTRD Data for Enhancing Randomized and Non-Randomized Patient-Centered Outcomes Evidence Generation

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Mehdi Najafzadeh, PhD, MA, TRD
Project Status:
Awarded; Contract not executed
Project Type:
Research
Has Results

Comparing Three Treatments for Adults with Major Depression That Does Not Respond to First-Line Treatment -- The ASCERTAIN TRD Study

Massachusetts General Hospital
| Massachusetts
George Papakostas, MD
Project Status:
In PCORI Peer-Review Process
Project Type:
Research
Has Results

Comparing Ways to Help Veterans Manage Chronic Pain -- The VOICE Study

University of Minnesota Twin Cities
| Minnesota
Erin Krebs, MD, MPH
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research
Has Results

Comparing Ways to Decrease Severe Asthma Attacks among Black and Latinx Adults with Moderate to Severe Asthma -- The PREPARE Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Elliot Israel, MD
Project Status:
Completed; PCORI Public and Professional Abstracts Posted
Project Type:
Research

Helping People with Serious Mental Illness Stop Smoking

Massachusetts General Hospital
| Massachusetts
Eden Evins, MD, MPH
Project Status:
In PCORI Peer-Review Process
Project Type:
Research

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