Explore Our Portfolio

Search a repository of PCORI-funded comparative clinical effectiveness research (CER) studies, as well as projects that seek to encourage engagement in research, disseminate and implement PCORI-funded research findings, and improve the nation's capacity to conduct patient-centered CER, among others. Learn more about the Portfolio

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Status Project Status View definitions of the life cycle of an awarded project View Glossary
State State The state where the project originates, or where the primary institution or organization is located. View Glossary
Funding Opportunity Type
Health Condition Health Conditions These are the broad terms we use to categorize our funded research studies; specific diseases or conditions are included within the appropriate larger category. Note: not all of our funded projects focus on a single disease or condition; some touch on multiple diseases or conditions, research methods, or broader health system interventions. Such projects won’t be listed by a primary disease/condition and so won’t appear if you use this filter tool to find them. View Glossary
Population Populations PCORI is interested in research that seeks to better understand how different clinical and health system options work for different people. These populations are frequently studied in our portfolio or identified as being of interest by our stakeholders. View Glossary
Intervention Strategy Intervention Strategies PCORI funds comparative clinical effectiveness research (CER) studies that compare two or more options or approaches to health care, or that compare different ways of delivering or receiving care. View Glossary
Year Awarded Year Awarded The year that funding for the project was approved, or the year the proposal received a notice of award. View Glossary
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Displaying 1 - 22 of 22 results

Project Title
Project Status
Project Type

Supporting the Use of a Treatment Approach in Health Systems to Improve Outcomes for Adults with Moderate to Severe Asthma

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Elliot Israel, M.D.
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Learning to Predict Disease Trajectories

Harvard Pilgrim Health Care ,Inc.
| Massachusetts
Mei-Sing Ong, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Identification of Temporal Data Patterns Predictive of Adverse Outcomes in Patients with Diabetes

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Alexander Turchin, M.D., MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®

Can A/B Testing Be Adapted into an Ethical and Useful Approach to Patient-Centered Outcomes Research?

Memorial Sloan Kettering Cancer Center
| New York
James Flory, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Fast and Robust Weighting Methods for Targeted Comparative Effectiveness Research

President and Fellows of Harvard College
| Massachusetts
Jose Zubizarreta, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Transportability of Machine Learning-Enabled Confounding Control Methods Across EHR Databases

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Richard Wyss, PhD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Statistical Methods for Optimizing Dynamic Patient-Level Treatment and Monitoring Strategies

Rutgers University School of Public Health
| New Jersey
Jason Roy, PhD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Pragmatic Comparative Effectiveness Using Sequential Multiple Assignment Randomized Trials

University of Rochester
| New York
Abdus Wahed, PhD, MS, MA
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Improving Methods for Benchmarking and Joint Analysis for Observational Studies

President and Fellows of Harvard College
| Massachusetts
Issa Dahabreh, MD, ScD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Developing New Methods for Mediation Analysis Using Machine Learning

New York University
| New York
Ivan Diaz, PhD, MPH, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Developing Methods for Analyzing Clustered Observational Data When Death is a Semi-Competing Risk

The University of Texas Southwestern Medical Center
| Texas
Hong Zhu, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Using Machine Learning to Measure Treatment Effects over Time

Rutgers, The State University of New Jersey
| New Jersey
Liangyuan Hu, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Implementing Matching of Patients to Mental Healthcare Therapists’ Strengths

University of Massachusetts Amherst
| Massachusetts
Michael Constantino, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Putting an Online Weight Management Program in Place in Clinical and Community Settings

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Heather J. Baer, ScD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Expanding the Use of Reports That Capture Age-Related Problems to Improve Doctor-Patient Conversations in Community Cancer Clinics

The University of Texas MD Anderson Cancer Center
| Texas
Lisa Lowenstein, PhD, MPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Comparing Second-Line Medicines to Treat Type 2 Diabetes -- The BESTMED Study

Partners Healthcare Brigham and Women's Hospital
| Massachusetts
Alexander Turchin, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Research, Research Conducted Using PCORnet®
Has Results

Comparing the Effect of Four Diabetes Medicines on the Risk of Heart Disease among Patients with Type 2 Diabetes -- The CER-4-T2D Study

Brigham and Women's Hospital
| Massachusetts
Elisabetta Patorno, MD, DrPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

Expanding Effective Home Oxygen Management Strategies for Premature Infants

University of Massachusetts Medical School
| Massachusetts
Lawrence Rhein, MD, MPH
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Implementing Best-Practice, Patient-Centered Venous Thromboembolism (VTE) Prevention in Trauma Centers

Coalition for National Trauma Research
| Texas
Elliott Haut, MD, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Using a Learning Collaborative to Help Hospitals Support Patient Decisions about Orthopedic Care

Massachusetts General Hospital
| Massachusetts
Karen R. Sepucha, PhD
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)

Implementing Team-based Outpatient Palliative Care in Parkinson Foundation Centers of Excellence

University of Rochester
| New York
Benzi M. Kluger, MD, MS
Project Status:
In progress; Recruitment not applicable
Project Type:
Implementation Project (Limited Competition D&I PFA)
Has Results

Comparing One-Stage Versus Two-Stage Informed Consent for Clinical Trials

Sloan-Kettering Institute For Cancer Research
| New York
Andrew Vickers, DPhil
Project Status:
In progress; Recruitment not applicable
Project Type:
Research

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