Funding Opportunities

Open Opportunities

All open funding opportunities can be found below. If this is your first experience applying to PCORI for funding, we recommend that you begin on the What You Need to Know to Apply page. Please note each funding announcement has a distinct set of requirements and application templates that must be followed for your application to be reviewed and funded. Applicants are advised to utilize the full funding announcement PDF and the specific application guidelines for the specific funding announcements. Both are located within the link to the opportunities listed below. You can also learn more about our Upcoming Funding Opportunities.

Pharmacological Treatment for Anxiety Disorders in Children, Adolescents, and/or Young Adults - Cycle 1 2018
Key Dates	Type	Funds Available	Total Direct Costs
LOI: February 13, 2018 by 5 p.m. (ET) Application: May 16, 2018 by 5 p.m. (ET) Merit Review: August 2018	Research Award	Up to $40 million	$15 million

Pragmatic Clinical Studies to Evaluate Patient-Centered Outcomes - Cycle 1 2018
Key Dates	Type	Funds Available	Total Direct Costs
LOI: February 13, 2018 by 5 p.m. (ET) Application: May 16, 2018 by 5 p.m. (ET) Merit Review: August 2018	Research Award	$90 million	$10 million

Improving Methods for Conducting PCOR - Cycle 1 2018
Key Dates	Type	Funds Available	Total Direct Costs
LOI: February 13, 2018 by 5 p.m. (ET) Application: May 16, 2018 by 5 p.m. (ET) Merit Review: August 2018	Research Award	$12 million	$750,000

Limited PCORI Funding Announcement: Dissemination and Implementation of PCORI-Funded Patient-Centered Outcomes Research Results - Cycle 1 2018
Key Dates	Type	Funds Available	Total Direct Costs
LOI: February 13, 2018 by 5 p.m. (ET) Application: May 16, 2018 by 5 p.m. (ET) Merit Review: August 2018	Research Award	$9 million	Up to $1 million with clear and adequate justification (see relevant section of the PFA for more information)

Broad PCORI Funding Announcements - Cycle 1 2018 (for Addressing Disparities, Assessment of Options, Communication and Dissemination Research, Improving Healthcare Systems)
Key Dates	Type	Funds Available	Total Direct Costs
LOI: February 13, 2018 by 5 p.m. (ET) Application: May 16, 2018 by 5 p.m. (ET) Merit Review: August 2018	Research Award	See PFA for details	See PFA for details

Research-Related Conference Support for Planning of Individual Participant-Level Data Meta-Analysis (RRCS-IPD MA)
Key Dates	Type	Funds Available	Total Costs
Application: Reviews to be conducted on a rolling basis, as program funds allow	Research Support Award		Award total costs must not exceed $50,000

Engagement Award: Capacity Building
Key Dates	Type	Funds Available	Total Costs
LOI: June 1, 2018 by 5 p.m. (ET) Application: Full proposals are due 40 days after review and approval of the LOI.	Research Support Award		Award total costs may not exceed $250,000

Engagement Award: Conference Support
Key Dates	Type	Funds Available	Total Costs
LOI: Not required Application: June 1, 2018 by 5 p.m. (ET)	Research Support Award		Award total costs must not exceed $50,000

Engagement Award: Dissemination Initiative
Key Dates	Type	Funds Available	Total Costs
LOI: June 1, 2018 by 5:00 p.m. (ET) Application: Full proposals are due 40 days after review and approval of the LOI.	Research Support Award		Award total costs may not exceed $300,000

Upcoming Opportunities

PCORI Funding Announcement: Implementation of Effective Shared Decision Making Approaches in Practice Settings -- Cycle 2 2018
Key Dates	Type	Funds Available	Total Direct Costs
LOI: July 24, 2018 by 5 p.m. (ET) Application: October 10, 2018 by 5 p.m. (ET) Merit Review: December 2018	Research Dissemination and Implementation Award	$6.5 million	$1.5 million

Improving Methods for Conducting Patient-Centered Outcomes Research -- Cycle 2 2018
Key Dates	Type	Funds Available	Total Direct Costs
LOI: June 28, 2018 by 5 p.m. (ET) Application: September 25, 2018 by 5 p.m. (ET) Merit Review: December 2018	Research Award	$12 million	$750,000

Broad PCORI Funding Announcements -- Cycle 2 2018 (for Addressing Disparities, Assessment of Options, Communication and Dissemination Research, Improving Healthcare Systems)
Key Dates	Type	Funds Available	Total Costs
LOI: June 28, 2018 by 5 p.m. (ET) Application: September 25, 2018 by 5 p.m. (ET) Merit Review: December 2018	Research Award

Limited PCORI Funding Announcement: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results -- Cycle 2 2018
Key Dates	Type	Funds Available	Total Costs
LOI: June 21 2018 by 5 p.m. (ET) Application: August 30, 2018 by 5 p.m. (ET) Merit Review: October 2018	Research Dissemination and Implementation Award

Closed Opportunities

Pragmatic Clinical Studies to Evaluate Patient-Centered Outcomes - Cycle 3 2017
Key Dates	Type	Funds Available	Total Direct Costs
LOI: October 31, 2017 by 5 p.m. (ET) Application: February 6, 2018 by 5 p.m. (ET) Merit Review: April 2018	Research Award	Up to $90 million	$10 million

Broad PCORI Funding Announcements - Cycle 3 2017 (for Addressing Disparities, Assessment of Options, Communication and Dissemination Research, Improving Healthcare Systems)
Key Dates	Type	Funds Available	Total Direct Costs
LOI: October 31, 2017 by 5 p.m. (ET) Application: February 6, 2018 by 5 p.m. (ET) Merit Review: April 2018	Research Award	See PFA for details	See PFA for details

Improving Methods for Conducting PCOR - Cycle 3 2017
Key Dates	Type	Funds Available	Total Direct Costs
LOI: October 31, 2017 by 5 p.m. (ET) Application: February 6, 2018 by 5 p.m. (ET) Merit Review: April 2018	Research Award	$12 million	$750,000

Limited PCORI Funding Announcement: Dissemination and Implementation of PCORI-Funded Patient-Centered Outcomes Research Results - Cycle 3 2017
Key Dates	Type	Funds Available	Total Direct Costs
LOI: October 31, 2017 by 5 p.m. (ET) Application: February 6, 2018 by 5 p.m. (ET) Merit Review: April 2018	Research Award	$9 million	$350,000

Request for Applications: Atrial Fibrillation Strategically Focused Research Network
Key Dates	Type	Funds Available	Total Costs
LOI: November 30, 2017 by 5 p.m. (CT) Application: January 31, 2018 by 5 p.m. (CT)	Research Award	$5 million

Pragmatic Clinical Studies to Evaluate Patient-Centered Outcomes - Cycle 2 2017
Key Dates	Type	Funds Available	Total Direct Costs
LOI: July 25, 2017 by 5 p.m. (ET) Application: October 25, 2017 by 5 p.m. (ET) Merit Review: January 2018	Research Award	$90 million	$10 million

Medication-Assisted Treatment (MAT) Delivery for Pregnant Women with Substance Use Disorders Involving Prescription Opioids and/or Heroin - Cycle 2 2017
Key Dates	Type	Funds Available	Total Direct Costs
LOI: July 25, 2017 by 5 p.m. (ET) Application: October 25, 2017 by 5 p.m. (ET) Merit Review: January 2018	Research Award	Up to $16 million	$4 million

Symptom Management for Patients with Advanced Illness - Cycle 2 2017
Key Dates	Type	Funds Available	Total Direct Costs
LOI: July 25, 2017 by 5 p.m. (ET) Application: October 25, 2017 by 5 p.m. (ET) Merit Review: January 2018	Research Award	Up to $25 million	$2 million

Limited PCORI Funding Announcement: Dissemination and Implementation of PCORI-Funded Patient-Centered Outcomes Research Results - Cycle 2 2017
Key Dates	Type	Funds Available	Total Direct Costs
LOI: July 25, 2017 by 5 p.m. (ET) Application: October 25, 2017 by 5 p.m. (ET) Merit Review: January 2018	Research Award		$350,000

Limited PCORI Funding Announcement: Partnerships to Conduct Research within PCORnet (PaCR) - Cycle 2 2017
Key Dates	Type	Funds Available	Total Direct Costs
LOI: September 6, 2017 by 5 p.m. (ET) Application: December 6, 2017 by 5 p.m. (ET) Merit Review: February 2018	Research Award	Up to $21 million	$5 million

Strategies to Prevent Unsafe Opioid Prescribing in Primary Care among Patients with Acute or Chronic Noncancer Pain
Key Dates	Type	Funds Available	Total Costs
LOI: October 2, 2017 by 5 p.m. (ET) Application: January 10, 2018 by 5 p.m. (ET) Merit Review: March 2018	Research Award	$20 million	$5 million

PCORI Funding Announcement: Implementation of Effective Shared Decision Making Approaches in Practice Settings - Cycle 2 2017
Key Dates	Type	Funds Available	Total Direct Costs
LOI: October 2, 2017 by 5 p.m. (ET) Application: January 10, 2018 by 5 p.m. (ET) Merit Review: March 2018	Research Dissemination and Implementation Award	$6.5 million	$1.5 million

Pragmatic Clinical Studies to Evaluate Patient-Centered Outcomes - Cycle 1 2017
Key Dates	Type	Funds Available	Total Direct Costs
LOI: February 14, 2017 Application: May 17, 2017 Merit Review: August 2017	Research Award	$90 million	$10 million

Comparison of Surgical and Nonsurgical Options for Management of Chronic Nonspecific Low Back Pain - Cycle 1 2017
Key Dates	Type	Funds Available	Total Direct Costs
LOI: February 14, 2017 Application: May 17, 2017 Merit Review: August 2017	Research Award	$22 million	$15 million

Optimized Multidisciplinary Treatment Programs for Nonspecific Chronic Low Back Pain – Cycle 1 2017
Key Dates	Type	Funds Available	Total Direct Costs
LOI: February 14, 2017 Application: May 17, 2017 Merit Review: August 2017	Research Award	$50 million	$10 million

Improving Methods for Conducting PCOR - Cycle 1 2017
Key Dates	Type	Funds Available	Total Direct Costs
LOI: February 14, 2017 Application: May 17, 2017 Merit Review: August 2017	Research Award	$12 million	$750,000

Broad PCORI Funding Announcements - Cycle 1 2017
Key Dates	Type	Funds Available	Total Direct Costs
LOI: February 14th, 2017 by 5 p.m. (ET) Application: May 17th, 2017 by 5 p.m. (ET) Merit Review: August 2017	Research Award	See specific PFA for details	See specific PFA for details

Limited PCORI Funding Announcement: Dissemination and Implementation of PCORI-Funded Patient-Centered Outcomes Research Results - Cycle 1 2017
Key Dates	Type	Funds Available	Total Direct Costs
LOI: February 14, 2017 Application: May 17, 2017 Merit Review: August 2017	Research Dissemination and Implementation Award	$9 million annually	$350,000

Pragmatic Clinical Studies to Evaluate Patient-Centered Outcomes - Cycle 3 2016
Key Dates	Type	Funds Available	Total Direct Costs
LOI: September 14, 2016 Application: December 19, 2016 Merit Review: March 2017	Research Award	$90 million (additional $80 million for special emphasis topics)	$10 million

Treatment of Multiple Sclerosis - Cycle 3 2016
Key Dates	Type	Funds Available	Total Direct Costs
LOI: November 1, 2016 Application: February 7, 2017 Merit Review: April 2017	Research Award	$30 million	Question 1 - $10 million; Question 2 - $3 million; Question 3 - $5 million

Clinical Strategies for Managing and Reducing Long-Term Opioid Use for Chronic Pain – Cycle 3 2016
Key Dates	Type	Funds Available	Total Direct Costs
LOI: November 1, 2016 Application: February 7, 2017 Merit Review: April 2017	Research Award	$19 million	$10 million

Community-Based Palliative Care Delivery for Adult Patients with Advanced Illnesses and their Caregivers - Cycle 3 2016
Key Dates	Type	Funds Available	Total Direct Costs
LOI: September 14, 2016 Application: December 19, 2016 Merit Review: March 2017	Research Award	$48 million (total costs)	• Advance Care Planning: Not to exceed $6M per study • Models of Palliative Care Delivery: Not to exceed $10M per study

Strategies to Prevent Unsafe Opioid Prescribing in Primary Care among Patients with Acute or Chronic Non-Cancer Pain - Cycle 3 2016
Key Dates	Type	Funds Available	Total Costs
LOI: September 14, 2016 Application: December 19, 2016 Merit Review: March 2017	Research Award	$30 Million	$5 Million

Management of Care Transitions for Emerging Adults with Sickle Cell Disease
Key Dates	Type	Funds Available	Total Costs
LOI: September 14, 2016 Application: December 19, 2016 Merit Review: March 2017	Research Award	$25 million	$8.33 million

Assessment of Prevention, Diagnosis, and Treatment Options - Cycle 3 2016
Key Dates	Type	Funds Available	Total Direct Costs
LOI: September 14, 2016 Application: December 19, 2016 Merit Review: March 2017	Research Award	$32 million	$2 million

Improving Healthcare Systems - Cycle 3 2016
Key Dates	Type	Funds Available	Total Direct Costs
LOI: September 14, 2016 Application: December 19, 2016 Merit Review: March 2017	Research Award	$16 million	$5 million for large studies, $1.5 million for small studies

Communication and Dissemination Research - Cycle 3 2016
Key Dates	Type	Funds Available	Total Direct Costs
LOI: September 14, 2016 Application: December 19, 2016 Merit Review: March 2017	Research Award	$8 million	$1.5 million

Improving Methods for Conducting Patient-Centered Outcomes Research - Cycle 3 2016
Key Dates	Type	Funds Available	Total Direct Costs
LOI: September 14, 2016 Application: December 19, 2016 Merit Review: March 2017	Research Award	$12 million	$750,000

Addressing Disparities - Cycle 3 2016
Key Dates	Type	Funds Available	Total Direct Costs
LOI: September 14, 2016 Application: December 19, 2016 Merit Review: March 2017	Research Award	$8 million	$1.5 million

Limited PCORI Funding Announcement: Dissemination and Implementation of PCORI-Funded Patient-Centered Outcomes Research Results and Products in Real World Settings - Cycle 3 2016
Key Dates	Type	Funds Available	Total Direct Costs
LOI: September 14, 2016 Application: December 19, 2016 Merit Review: March 2017	Research Award	$2,000,000 per cycle	$300,000

Pragmatic Clinical Studies to Evaluate Patient-Centered Outcomes - Cycle 2 2016
Key Dates	Type	Funds Available	Total Direct Costs
LOI: May 4, 2016 Application: August 8, 2016 Merit Review: November 2016	Research Award	$90 million	$10 million

Comparison of Surgical and Nonsurgical Options for Management of Nonspecific Chronic Low Back Pain - Cycle 2 2016
Key Dates	Type	Funds Available	Total Direct Costs
LOI: May 4, 2016 Application: August 8, 2016 Merit Review: November 2016	Research Award	$22 million	$15 million

Patient-Centered Outcomes Research (PCOR) for Treatment Options in Uterine Fibroids: Developing a Prospective Multi-Center Practice-based Clinical Registry (P50)
Key Dates	Type	Funds Available	Total Costs
LOI: November 15, 2013 Application: December 16, 2013	Research Award	$20 million	Up to $4 million total costs/year (MAXIMUM BUDGET)

Pipeline to Proposal Awards Tier I Cycle 2 - Pre-Engagement/Community Projects
Key Dates	Type	Funds Available	Total Costs
LOI: December 23, 2014 Application: February 20, 2015, 5pm ET	Research Support Award	$15,000

Pipeline to Proposal Awards Tier I Cycle 3 - Pre-Engagement/Community Projects
Key Dates	Type	Funds Available	Total Costs
LOI: January 20, 2016 Application: April 18, 2016 by 11:59 p.m. ET	Research Support Award	$15,000

Pipeline to Proposal Awards Independent Tier III – Proposal Development Projects
Key Dates	Type	Funds Available	Total Costs
LOI: June 30, 2016, 11:59 p.m. (ET) Application: September 30, 2016	Research Support Award

Pipeline to Proposal Awards Tier A Pre-Engagement/Community Projects
Key Dates	Type	Funds Available	Total Costs
LOI: April 20, 2017 Application: June 30, 2017	Research Support Award	$50,000

Notices

Cycle 1 2018 Funding Announcements

Tuesday, January 16, 2018—PCORI's Online System opened today for the submission of Letters of Intent (LOIs) for a new round of PCORI Funding Announcements (PFAs).

We are accepting LOIs for our Pragmatic Clinical Studies initiative, our Methods and Dissemination and Implementation programs, and four Broad funding announcements under our National Priorities for Research. We are also accepting research proposals that compare the effectiveness of two or more pharmacological treatments for anxiety disorders in children, adolescents, and young adults.

LOIs for all PFAs were due...

Eugene Washington PCORI Engagement Awards

The Eugene Washington PCORI Engagement Awards offer three different funding opportunities: Engagement Award: Capacity Building, Engagement Award: Conference Support, and Engagement Award: Dissemination Initiative. It is important that you click on the correct link to enter the application system because the application process is different.

If you are interested in an Engagement Award: Capacity Building or Engagement Award: Dissemination Initiative, you must first submit a Letter of Inquiry (LOI). The next...

Dissemination and Implementation of PCORI-Funded Patient-Centered Outcomes Research Results

PCORI seeks to support the dissemination and implementation of results from PCORI-funded comparative effectiveness research studies. PCORI recognizes that the generation of evidence will be useful only if research results reach those who can use this information in their health decisions.

This limited PCORI Funding Announcement (PFA) is designed to encourage PCORI awardees and their patient and stakeholder partners, who have completed their research and who have strategic plans for initial dissemination and implementation activities, to apply for funding to support these efforts....