Funding Opportunities

Open Opportunities

Applicant and Awardee FAQs Related to COVID-19: PCORI is working to assist applicants and awardees in finding solutions that may help address issues related to disruptions associated with COVID-19, including general guidance and information about funding application deadline extensions. View the FAQs

All open funding opportunities can be found below. First-time funding applicants are advised to utilize the full funding announcement PDF and the specific application guidelines for each funding opportunity.

Engagement Award: Capacity Building
Key Dates Type Funds Available Total Costs
Letter of Inquiry (LOI): May 1, 2020, by 5 p.m. (ET)
Application: By invitation only; Full proposals are due 40 calendar days after LOI approval and invitation
Research Support Award Award total costs may not exceed $250,000
Engagement Award: Dissemination Initiative
Key Dates Type Funds Available Total Costs
Letter of Inquiry (LOI): May 1, 2020, by 5 p.m. (ET)
Application: By invitation only; Full proposals are due 40 calendar days after LOI approval and invitation
Research Support Award Award total costs may not exceed $250,000
Engagement Award: Stakeholder Convening Support
Key Dates Type Funds Available Total Costs
Letter of Inquiry (LOI): May 1, 2020, by 5 p.m. (ET)
Application: By invitation only; Full proposals are due 40 calendar days after LOI approval and invitation
Research Support Award Award total costs may not exceed $100,000
Broad PCORI Funding Announcements -- Cycle 1 2020 (for Addressing Disparities, Assessment of Options, Communication and Dissemination Research, Improving Healthcare Systems)
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): February 4, 2020 by 5 p.m. (ET)
Application: May 5, 2020 by 5 p.m. (ET)
Merit Review: July 2020
Research Award Assessment of Prevention, Diagnosis, and Treatment Options ($32 million); Improving Healthcare Systems ($16 million); Addressing Disparities ($8 million); Communication and Dissemination Research ($8 million) Addressing Disparities; Assessment of Prevention, Diagnosis, and Treatment Options; Improving Healthcare Systems: $3 million for small studies; $5 million for large studies • Communication and Dissemination Research: $2 million
Improving Methods for Conducting Patient-Centered Outcomes Research -- Cycle 1 2020
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): February 4, 2020 by 5 p.m. (ET)
Application: May 5, 2020 by 5 p.m. (ET)
Merit Review: July 2020
Research Award $12 million (See PFA for more details) $750,000
Limited PCORI Funding Announcement: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results -- Cycle 1 2020
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): January 28, 2020 by 5 p.m. (ET)
Application: April 7, 2020 by 5 p.m. (ET)
Merit Review: May 2020
Implementation Award $9 million per year Up to $1 million (see relevant section of the PFA for more information)

Upcoming Opportunities

Applicant and Awardee FAQs Related to COVID-19: PCORI is working to assist applicants and awardees in finding solutions that may help address issues related to disruptions associated with COVID-19, including general guidance and information about funding cycle and submission deadline changes. View the FAQs

Observational Analyses of Second-Line Pharmacological Agents in Type 2 Diabetes – Cycle 2 2020
Key Dates Type Funds Available Total Direct Costs
Application: September 1, 2020 at 5pm ET
Merit Review: November 2020
Research Award $20 million Up to $4 million
Limited Competition PCORI Funding Announcement: Conducting Rare Disease Research using PCORnet® – Cycle 2 2020
Key Dates Type Funds Available Total Direct Costs
Application: September 1, 2020 at 5pm ET
Merit Review: November 2020
Research Award $25 million $3.5 million
Implementation of Effective Shared Decision Making Approaches in Practice Settings – Cycle 2 2020
Key Dates Type Funds Available Total Direct Costs
Application: August 31, 2020 at 5pm ET
Merit Review: October 2020
Implementation Award See PFA for details (available May 5, 2020) $1.5 million
Limited PCORI Funding Announcement: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results – Cycle 2 2020
Key Dates Type Funds Available Total Direct Costs
Application: August 31, 2020 at 5pm ET
Merit Review: October 2020
Implementation Award See PFA for more details (available May 5, 2020) Up to $1 million (see relevant section of the PFA for more information, available May 5, 2020)
Phased Large Awards for Comparative Effectiveness Research – Cycle 3 2020
Key Dates Type Funds Available Total Direct Costs
Application: January 12, 2021 at 5pm ET
Merit Review:
Research Award $150 million $22 million (Feasibility phase: $2 million; Full-scale study phase: $20 million)
Broad PCORI Funding Announcements – Cycle 3 2020 (for Addressing Disparities, Assessment of Options, Communication and Dissemination Research, Improving Healthcare Systems)
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): September 29, 2020 at 5pm ET

Application: January 12, 2021 at 5pm ET
Merit Review: April 2021
Research Award See PFA for details (available September 1, 2020) See PFA for details (available September 1, 2020)
Improving Methods for Conducting Patient-Centered Outcomes Research -- Cycle 3 2020
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): September 29, 2020 by 5pm ET

Application: January 12, 2021 by 5pm ET
Merit Review: April 2021
Research Award See PFA for details (available September 1, 2020) See PFA for details (available September 1, 2020)
Limited PCORI Funding Announcement: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results – Cycle 3 2020
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): September 22, 2020 at 5pm ET

Application: December 1, 2020 at 5pm ET
Merit Review: February 2021
Implementation Award See PFA for more details (available September 1, 2020) Up to $1 million (see relevant section of the PFA for more information, available September 1, 2020)
Broad PCORI Funding Announcements -- Cycle 1 2021
Key Dates Type Funds Available Total Direct Costs
Application: May 4, 2021 at 5pm ET
Merit Review: July 2021
Research Award See PFA for details (available January 5, 2021) See PFA for details (available January 5, 2021)
Improving Methods for Conducting Patient-Centered Outcomes Research -- Cycle 1 2021
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): Febraury 2, 2021 at 5pm ET

Application: May 4, 2021 at 5pm ET
Merit Review: July 2021
Research Award See PFA for details (available January 5, 2021) See PFA for details (available January 5, 2021)
Limited PCORI Funding Announcement: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results – Cycle 1 2021
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): January 26, 2021 at 5pm ET

Application: April 6, 2021 at 5pm ET
Merit Review: June 2021
Implementation Award See PFA for more details (available January 5, 2021) Up to $1 million (see relevant section of the PFA for more information, available January 5, 2021)
Upcoming Initiative -- Cycle 2 2021
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): June 21, 2021 at 5pm ET

Application: August 31, 2021 at 5pm ET
Merit Review: November 2021
Research Award See PFA for details (available May 4, 2021) See PFA for details (available May 4, 2021)
Implementation of Effective Shared Decision Making Approaches in Practice Settings -- Cycle 2 2021
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): June 22, 2021 at 5pm ET

Application: August 31, 2021 at 5pm ET
Merit Review: October 2021
Implementation Award $6.5 million $1.5 million
Limited PCORI Funding Announcement: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results – Cycle 2 2021
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): June 22, 2021 at 5pm ET

Application: August 31, 2021 at 5pm ET
Merit Review: October 2021
Implementation Award See PFA for more details (available May 4, 2021) Up to $1 million (see relevant section of the PFA for more information, available May 4, 2021)
Upcoming Broad Research Initiative -- Cycle 3 2021
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): October 5, 2021 at 5pm ET

Application: January 11, 2022 at 5pm ET
Merit Review: April 2022
Research Award See PFA for details (available September 7, 2021) See PFA for details (available September 7, 2021)
Improving Methods for Conducting Patient-Centered Outcomes Research -- Cycle 3 2021
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): October 5, 2021 at 5pm ET

Application: January 11, 2022 at 5pm ET
Merit Review: April 2022
Research Award See PFA for details (available September 7, 2021) See PFA for details (available September 7, 2021)
Limited PCORI Funding Announcement: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results – Cycle 3 2021
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): September 28, 2021 at 5pm ET

Application: December 7, 2021 at 5pm ET
Merit Review: February 2022
Implementation Award See PFA for more details (available September 7, 2021) Up to $1 million (see relevant section of the PFA for more information, available September 7, 2021)

Closed Opportunities

Applicant and Awardee FAQs Related to COVID-19 All Closed Funding Opportunities

Broad PCORI Funding Announcements -- Cycle 3 2019 (for Addressing Disparities, Assessment of Options, Communication and Dissemination Research, Improving Healthcare Systems)
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): October 1, 2019 by 5 p.m. (ET)

Application: January 14, 2020 by 5 p.m. (ET)
Merit Review: April 2020
Research Award See PFA for details Addressing Disparities; Assessment of Prevention, Diagnosis, and Treatment Options; and Improving Healthcare Systems: $3 million; Communication & Dissemination Research: $2 million
Improving Methods for Conducting Patient-Centered Outcomes Research -- Cycle 3 2019
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): October 1, 2019 by 5 p.m. (ET)

Application: January 14, 2020 by 5 p.m. (ET)
Merit Review: April 2020
Research Award $12 million $750,000
Limited PCORI Funding Announcement: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results -- Cycle 3 2019
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): September 24, 2019 by 5 p.m. (ET)

Application: December 3, 2019 by 5 p.m. (ET)
Merit Review: February 2020
Implementation Award See PFA for more details Up to $1 million (see relevant section of the PFA for more information)
Research-Related Conference Support for Planning of Individual Participant-Level Data Meta-Analysis (RRCS-IPD MA)
Key Dates Type Funds Available Total Costs
Application: Reviews to be conducted on a rolling basis, as program funds allow
Research Support Award Award total costs must not exceed $50,000
Engagement Award: Accelerating the Adoption of Tools & Resources
Key Dates Type Funds Available Total Costs
Letter of Inquiry (LOI): November 15, 2019 by 5 p.m. (ET)

Application: Full proposals are due 40 days after review and approval of the LOI.
Research Support Award Award total costs may not exceed $100,000
Engagement Award: Community Convening Around Patient-Centered Outcomes Research (PCOR)
Key Dates Type Funds Available Total Costs
Letter of Inquiry (LOI): November 15, 2019 by 5 p.m. (ET)

Application: Full proposals are due 40 days after review and approval of the LOI.
Research Support Award Award total costs may not exceed $100,000
Treatment Options for Age-Related Hearing Loss -- Cycle 2 2019
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): May 29, 2019 by 5 p.m. (ET)

Application: September 4, 2019 by 5 p.m. (ET)
Merit Review: November 2019
Research Award $12 million $2 million
Improving Methods for Conducting Patient-Centered Outcomes Research -- Cycle 2 2019
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): May 29, 2019 by 5 p.m. (ET)

Application: September 4, 2019 by 5 p.m. (ET)
Merit Review: November 2019
Research Award $12 million $750,000
Broad PCORI Funding Announcements -- Cycle 2 2019 (for Addressing Disparities, Assessment of Options, Communication and Dissemination Research, Improving Healthcare Systems)
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): May 29, 2019 by 5 p.m. (ET)

Application: September 4, 2019 by 5 p.m. (ET)
Merit Review: November 2019
Research Award See PFA for details Addressing Disparities; Assessment of Prevention, Diagnosis, and Treatment Options; and Improving Healthcare Systems: $3 million; Communication & Dissemination Research: $2 million
Limited PCORI Funding Announcement: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results -- Cycle 2 2019
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): June 19, 2019 by 5 p.m. (ET)

Application: August 30, 2019 by 5 p.m. (ET)
Merit Review: October 2019
Implementation Award See PFA for more details Up to $1 million (see relevant section of the PFA for more information)
Implementation of Effective Shared Decision Making Approaches in Practice Settings -- Cycle 2 2019
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): June 19, 2019 by 5 p.m. (ET)

Application: August 30, 2019 by 5 p.m. (ET)
Merit Review: October 2019
Implementation Award $6.5 million $1.5 million
Engagement Award: Conference Support
Key Dates Type Funds Available Total Costs
Letter of Inquiry (LOI): A Letter of Inquiry is not required.

Application: To be announced.
Research Support Award Award total costs must not exceed $50,000
Treatment of Posttraumatic Stress Disorder (PTSD) in Adults -- Cycle 1 2019
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): January 31, 2019 by 5 p.m. (ET)

Application: April 24, 2019 by 5 p.m. (ET)
Merit Review: July 2019
Research Award $15 million $5 million
Treatment Options for Age-Related Hearing Loss -- Cycle 1 2019
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): January 31, 2019 by 5 p.m. (ET)

Application: April 24, 2019 by 5 p.m. (ET)
Merit Review: July 2019
Research Award Up to $12 million $2 million
Treatment of Anxiety in Children, Adolescents, and/or Young Adults -- Cycle 1 2019
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): January 31, 2019 by 5 p.m. (ET)

Application: April 24, 2019 by 5 p.m. (ET)
Merit Review: July 2019
Research Award Up to $20 million $5 million
Limited PCORI Funding Announcement: Partnerships to Conduct Research within PCORnet (PaCR) -- Cycle 1 2019
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): May 13, 2019 by 5 p.m. (ET)

Application: July 25, 2019 by 5 p.m. (ET)
Merit Review: September 2019
Research Award $6 million $2 million
Broad PCORI Funding Announcements -- Cycle 1 2019 (for Addressing Disparities, Assessment of Options, Communication and Dissemination Research, Improving Healthcare Systems)
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): January 31, 2019 by 5 p.m. (ET)

Application: April 24, 2019 by 5 p.m. (ET)
Merit Review: July 2019
Research Award See PFA for details See PFA for details
Improving Methods for Conducting Patient-Centered Outcomes Research -- Cycle 1 2019
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): January 31, 2019 by 5 p.m. (ET)

Application: April 24, 2019 by 5 p.m. (ET)
Merit Review: July 2019
Research Award See PFA for details See PFA for details
Implementation of Findings from PCORI's Major Research Investments -- Cycle 1 2019
Key Dates Type Funds Available Total Costs
Letter of Intent (LOI): January 24, 2019 by 5 p.m. (ET)

Application: April 4, 2019 by 5 p.m. (ET)
Merit Review: June 2019
Implementation Award $8 million Up to $2.5 million
Limited PCORI Funding Announcement: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results -- Cycle 1 2019
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): January 24, 2019 by 5 p.m. (ET)

Application: April 4, 2019 by 5 p.m. (ET)
Merit Review: June 2019
Implementation Award See PFA for more details Up to $1 million (see relevant section of the PFA for more information)
Broad PCORI Funding Announcements -- Cycle 3 2018 (for Addressing Disparities, Assessment of Prevention, Diagnosis, and Treatment Options, Communication and Dissemination Research, and Improving Healthcare Systems)
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): November 6, 2018 by 5 p.m. (ET)

Application: February 12, 2019 by 5 p.m. (ET)
Merit Review: May 2019
Research Award See PFA for details $3 million (AD, APDTO, IHS); $2 million (CDR)
Improving Methods for Conducting Patient-Centered Outcomes Research -- Cycle 3 2018
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): November 6, 2018 by 5 p.m. (ET)

Application: February 12, 2019 by 5 p.m. (ET)
Merit Review: May 2019
Research Award $12 million $750,000
Limited PCORI Funding Announcement: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results -- Cycle 3 2018
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): November 6, 2018 by 5 p.m. (ET)

Application: January 16, 2019 by 5 p.m. (ET)
Merit Review: March 2019
Implementation Award See PFA for more details Up to $1 million with clear and adequate justification (see relevant section of the PFA for more information)
PPRN Limited Competition Award*
Key Dates Type Funds Available Total Costs
Application: December 18, 2018, by 5 pm (ET)
Research Support Award Award total costs may not exceed $350,000
Psychosocial Interventions with Office-Based Opioid Treatment for Opioid Use Disorder -- Cycle 2 2018
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): June 28, 2018 by 5 p.m. (ET)

Application: September 25, 2018 by 5 p.m. (ET)
Merit Review: December 2018
Research Award $25 million $4 million
Symptom Management for Patients with Advanced Illness -- Cycle 2 2018
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): June 28, 2018 by 5 p.m. (ET)

Application: September 25, 2018 by 5 p.m. (ET)
Merit Review: December 2018
Research Award $22 million $2 million
Improving Methods for Conducting Patient-Centered Outcomes Research -- Cycle 2 2018
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): June 28, 2018 by 5 p.m. (ET)

Application: September 25, 2018 by 5 p.m. (ET)
Merit Review: December 2018
Research Award $12 million $750,000
Medication-Assisted Treatment (MAT) Delivery for Pregnant Women with Substance Use Disorders Involving Prescription Opioids and/or Heroin -- Cycle 2 2018
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): June 28, 2018 by 5 p.m. (ET)

Application: September 25, 2018 by 5 p.m. (ET)
Merit Review: December 2018
Research Award Up to $6 million $4 million
Broad PCORI Funding Announcements -- Cycle 2 2018 (for Addressing Disparities, Assessment of Options, Communication and Dissemination Research, Improving Healthcare Systems)
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): June 28, 2018 by 5 p.m. (ET)

Application: September 25, 2018 by 5 p.m. (ET)
Merit Review: December 2018
Research Award See PFA description for details
Limited PCORI Funding Announcement: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results -- Cycle 2 2018
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): June 21, 2018 by 5 p.m. (ET)

Application: August 30, 2018 by 5 p.m. (ET)
Merit Review: October 2018
Implementation Award $9 million Up to $1 million with clear and adequate justification (see relevant section of the PFA for more information)
PCORI Funding Announcement: Implementation of Effective Shared Decision Making Approaches in Practice Settings -- Cycle 2 2018
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): July 24, 2018 by 5 p.m. (ET)

Application: October 10, 2018 by 5 p.m. (ET)
Merit Review: December 2018
Implementation Award $6.5 million $1.5 million
Pharmacological Treatment for Anxiety Disorders in Children, Adolescents, and/or Young Adults - Cycle 1 2018
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): February 13, 2018 by 5 p.m. (ET)

Application: May 16, 2018 by 5 p.m. (ET)
Merit Review: August 2018
Research Award Up to $40 million $15 million
Pragmatic Clinical Studies to Evaluate Patient-Centered Outcomes - Cycle 1 2018
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): February 13, 2018 by 5 p.m. (ET)

Application: May 16, 2018 by 5 p.m. (ET)
Merit Review: August 2018
Research Award $90 million $10 million
Improving Methods for Conducting PCOR - Cycle 1 2018
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): February 13, 2018 by 5 p.m. (ET)

Application: May 16, 2018 by 5 p.m. (ET)
Merit Review: August 2018
Research Award $12 million $750,000
Limited PCORI Funding Announcement: Dissemination and Implementation of PCORI-Funded Patient-Centered Outcomes Research Results - Cycle 1 2018
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): February 13, 2018 by 5 p.m. (ET)

Application: May 16, 2018 by 5 p.m. (ET)
Merit Review: August 2018
Dissemination and Implementation Award $9 million Up to $1 million with clear and adequate justification (see relevant section of the PFA for more information)
Broad PCORI Funding Announcements - Cycle 1 2018 (for Addressing Disparities, Assessment of Options, Communication and Dissemination Research, Improving Healthcare Systems)
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): February 13, 2018 by 5 p.m. (ET)

Application: May 16, 2018 by 5 p.m. (ET)
Merit Review: August 2018
Research Award See PFA for details See PFA for details
Pragmatic Clinical Studies to Evaluate Patient-Centered Outcomes - Cycle 3 2017
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): October 31, 2017 by 5 p.m. (ET)

Application: February 6, 2018 by 5 p.m. (ET)
Merit Review: April 2018
Research Award Up to $90 million $10 million
Broad PCORI Funding Announcements - Cycle 3 2017 (for Addressing Disparities, Assessment of Options, Communication and Dissemination Research, Improving Healthcare Systems)
Key Dates Type Funds Available Total Direct Costs
Application: February 6, 2018 by 5 p.m. (ET)
Merit Review: April 2018
Research Award See PFA for details See PFA for details
Improving Methods for Conducting PCOR - Cycle 3 2017
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): October 31, 2017 by 5 p.m. (ET)

Application: February 6, 2018 by 5 p.m. (ET)
Merit Review: April 2018
Research Award $12 million $750,000
Limited PCORI Funding Announcement: Dissemination and Implementation of PCORI-Funded Patient-Centered Outcomes Research Results - Cycle 3 2017
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): October 31, 2017 by 5 p.m. (ET)

Application: February 6, 2018 by 5 p.m. (ET)
Merit Review: April 2018
Research Award $9 million $350,000
Request for Applications: Atrial Fibrillation Strategically Focused Research Network
Key Dates Type Funds Available Total Costs
Application: January 31, 2018 by 5 p.m. (CT)
Research Award $5 million
Pragmatic Clinical Studies to Evaluate Patient-Centered Outcomes - Cycle 2 2017
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): July 25, 2017 by 5 p.m. (ET)

Application: October 25, 2017 by 5 p.m. (ET)
Merit Review: January 2018
Research Award $90 million $10 million
Medication-Assisted Treatment (MAT) Delivery for Pregnant Women with Substance Use Disorders Involving Prescription Opioids and/or Heroin - Cycle 2 2017
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): July 25, 2017 by 5 p.m. (ET)

Application: October 25, 2017 by 5 p.m. (ET)
Merit Review: January 2018
Research Award Up to $16 million $4 million
Symptom Management for Patients with Advanced Illness - Cycle 2 2017
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): July 25, 2017 by 5 p.m. (ET)

Application: October 25, 2017 by 5 p.m. (ET)
Merit Review: January 2018
Research Award Up to $25 million $2 million
Limited PCORI Funding Announcement: Dissemination and Implementation of PCORI-Funded Patient-Centered Outcomes Research Results - Cycle 2 2017
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): July 25, 2017 by 5 p.m. (ET)

Application: October 25, 2017 by 5 p.m. (ET)
Merit Review: January 2018
Research Award $350,000
Limited PCORI Funding Announcement: Partnerships to Conduct Research within PCORnet (PaCR) - Cycle 2 2017
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): September 6, 2017 by 5 p.m. (ET)

Application: December 6, 2017 by 5 p.m. (ET)
Merit Review: February 2018
Research Award Up to $21 million $5 million
Strategies to Prevent Unsafe Opioid Prescribing in Primary Care among Patients with Acute or Chronic Noncancer Pain
Key Dates Type Funds Available Total Costs
Application: January 10, 2018 by 5 p.m. (ET)
Merit Review: March 2018
Research Award $20 million $5 million
PCORI Funding Announcement: Implementation of Effective Shared Decision Making Approaches in Practice Settings - Cycle 2 2017
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): October 2, 2017 by 5 p.m. (ET)

Application: January 10, 2018 by 5 p.m. (ET)
Merit Review: March 2018
Dissemination and Implementation Award $6.5 million $1.5 million
Pragmatic Clinical Studies to Evaluate Patient-Centered Outcomes - Cycle 1 2017
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI): February 14th, 2017

Application: May 17, 2017
Merit Review: August 2017
Research Award $90 million $10 million
Comparison of Surgical and Nonsurgical Options for Management of Chronic Nonspecific Low Back Pain - Cycle 1 2017
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI):

Application: May 17, 2017
Merit Review: August 2017
Research Award $22 million $15 million
Optimized Multidisciplinary Treatment Programs for Nonspecific Chronic Low Back Pain – Cycle 1 2017
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI):

Application: May 17, 2017
Merit Review: August 2017
Research Award $50 million $10 million
Improving Methods for Conducting PCOR - Cycle 1 2017
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI):

Application: May 17, 2017
Merit Review: August 2017
Research Award $12 million $750,000
Broad PCORI Funding Announcements - Cycle 1 2017
Key Dates Type Funds Available Total Direct Costs
Application: May 17th, 2017 by 5 p.m. (ET)
Merit Review: August 2017
Research Award See specific PFA for details See specific PFA for details
Limited PCORI Funding Announcement: Dissemination and Implementation of PCORI-Funded Patient-Centered Outcomes Research Results - Cycle 1 2017
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI):

Application: May 17, 2017
Merit Review: August 2017
Dissemination and Implementation Award $9 million annually $350,000
Pragmatic Clinical Studies to Evaluate Patient-Centered Outcomes - Cycle 3 2016
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI):

Application: December 19, 2016
Merit Review: March 2017
Research Award $90 million (additional $80 million for special emphasis topics) $10 million
Treatment of Multiple Sclerosis - Cycle 3 2016
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI):

Application: February 7, 2017
Merit Review: April 2017
Research Award $30 million Question 1 - $10 million; Question 2 - $3 million; Question 3 - $5 million
Clinical Strategies for Managing and Reducing Long-Term Opioid Use for Chronic Pain – Cycle 3 2016
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI):

Application: February 7, 2017
Merit Review: April 2017
Research Award $19 million $10 million
Community-Based Palliative Care Delivery for Adult Patients with Advanced Illnesses and their Caregivers - Cycle 3 2016
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI):

Application: December 19, 2016
Merit Review: March 2017
Research Award $48 million (total costs) • Advance Care Planning: Not to exceed $6M per study • Models of Palliative Care Delivery: Not to exceed $10M per study
Strategies to Prevent Unsafe Opioid Prescribing in Primary Care among Patients with Acute or Chronic Non-Cancer Pain - Cycle 3 2016
Key Dates Type Funds Available Total Costs
Letter of Intent (LOI):

Application: December 19, 2016
Merit Review: March 2017
Research Award $30 Million $5 Million
Management of Care Transitions for Emerging Adults with Sickle Cell Disease
Key Dates Type Funds Available Total Costs
Letter of Intent (LOI):

Application: December 19, 2016
Merit Review: March 2017
Research Award $25 million $8.33 million
Assessment of Prevention, Diagnosis, and Treatment Options - Cycle 3 2016
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI):

Application: December 19, 2016
Merit Review: March 2017
Research Award $32 million $2 million
Improving Healthcare Systems - Cycle 3 2016
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI):

Application: December 19, 2016
Merit Review: March 2017
Research Award $16 million $5 million for large studies, $1.5 million for small studies
Communication and Dissemination Research - Cycle 3 2016
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI):

Application: December 19, 2016
Merit Review: March 2017
Research Award $8 million $1.5 million
Improving Methods for Conducting Patient-Centered Outcomes Research - Cycle 3 2016
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI):

Application: December 19, 2016
Merit Review: March 2017
Research Award $12 million $750,000
Addressing Disparities - Cycle 3 2016
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI):

Application: December 19, 2016
Merit Review: March 2017
Research Award $8 million $1.5 million
Limited PCORI Funding Announcement: Dissemination and Implementation of PCORI-Funded Patient-Centered Outcomes Research Results and Products in Real World Settings - Cycle 3 2016
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI):

Application: December 19, 2016
Merit Review: March 2017
Research Award $2,000,000 per cycle $300,000
Pragmatic Clinical Studies to Evaluate Patient-Centered Outcomes - Cycle 2 2016
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI):

Application: August 8, 2016
Merit Review: November 2016
Research Award $90 million $10 million
Comparison of Surgical and Nonsurgical Options for Management of Nonspecific Chronic Low Back Pain - Cycle 2 2016
Key Dates Type Funds Available Total Direct Costs
Letter of Intent (LOI):

Application: August 8, 2016
Merit Review: November 2016
Research Award $22 million $15 million
Patient-Centered Outcomes Research (PCOR) for Treatment Options in Uterine Fibroids: Developing a Prospective Multi-Center Practice-based Clinical Registry (P50)
Key Dates Type Funds Available Total Costs
Letter of Intent (LOI):

Application: December 16, 2013
Research Award $20 million Up to $4 million total costs/year (MAXIMUM BUDGET)
Pipeline to Proposal Awards Tier I Cycle 2 - Pre-Engagement/Community Projects
Key Dates Type Funds Available Total Costs
Letter of Intent (LOI):

Application: February 20, 2015, 5pm ET
Research Support Award $15,000
Pipeline to Proposal Awards Tier I Cycle 3 - Pre-Engagement/Community Projects
Key Dates Type Funds Available Total Costs
Letter of Intent (LOI):

Application: April 18, 2016 by 11:59 p.m. ET
Research Support Award $15,000
Pipeline to Proposal Awards Independent Tier III – Proposal Development Projects
Key Dates Type Funds Available Total Costs
Application: September 30, 2016
Research Support Award
Pipeline to Proposal Awards Tier A Pre-Engagement/Community Projects
Key Dates Type Funds Available Total Costs
Letter of Intent (LOI):

Application: June 30, 2017
Research Support Award $50,000