Funding Opportunities

PCORI funds patient-centered comparative clinical effectiveness research (CER), issuing funding opportunity announcements several times each year. PCORI also funds projects that support CER, such as methodology studies, as well as projects that support engagement in research and dissemination and implementation of PCORI-funded research findings. Use the search/filters below to find available funding opportunities and take advantage of the following resources:

New Application Portal: PCORI Connect 

A PCORI-branded document folder sits on a table

Learn about PCORI Connect, our new, streamlined portal for Letters of Intent, applications and award management for PCORI funding.

More Applicant/Awardee Resources

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Title LOI Deadline Application Deadline
Sept. 9, 2026 Jan. 12, 2027
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April 28, 2026 Sept. 1, 2026
April 28, 2026 Sept. 1, 2026

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Get weekly updates about opportunities to apply for funding, newly funded research and engagement projects, results of PCORI-funded research, webinars and other news.