Funding Opportunities

Open Opportunities

Letters of Intent due Tuesday, September 28
Letters of Intent due Friday, October 1
Letters of Intent due Tuesday, October 5
Phased Large Awards for Comparative Effectiveness Research -- Cycle 3 2021
Key Dates Type Total Direct Costs
Letter of Intent (LOI): October 5, 2021 at 5pm ET
Application: January 11, 2022 at 5pm ET
Research Award $22 million (Feasibility phase: $2 million; Full-scale study phase: $20 million)
Comparative Effectiveness of Multimodal Interventions to Prevent Osteoporotic Fractures -- Cycle 3 2021
Key Dates Type Total Direct Costs
Letter of Intent (LOI): October 5, 2021 by 5pm ET
Application: January 11, 2022 by 5pm ET
Research Award Up to $10 million
Comparative Effectiveness of Novel Pharmacologic and Evidence-Based Nonpharmacologic Treatments for Migraine Prevention -- Cycle 3 2021
Key Dates Type Total Direct Costs
Letter of Intent (LOI): October 5, 2021 by 5pm ET
Application: January 11, 2022 by 5pm ET
Research Award Up to $10 million
Healthy Aging: Optimizing Physical and Mental Functioning Across the Aging Continuum -- Cycle 3 2021
Key Dates Type Total Direct Costs
Letter of Intent (LOI): October 5, 2021 by 5pm ET
Application: January 11, 2022 by 5pm ET
Research Award Up to $5 million
Broad PCORI Funding Announcements -- Cycle 3 2021
Key Dates Type Total Direct Costs
Letter of Intent (LOI): October 5, 2021 at 5pm ET
Application: January 11, 2022 at 5pm ET
Research Award Addressing Disparities; Assessment of Prevention, Diagnosis, and Treatment Options; and Improving Healthcare Systems: up to $3 million (Small) - up to $5 million (Large) — Communication & Dissemination Research: up to $2 million
Improving Methods for Conducting Patient-Centered Outcomes Research -- Cycle 3 2021
Key Dates Type Total Direct Costs
Letter of Intent (LOI): October 5, 2021 at 5pm ET
Application: January 11, 2022 at 5pm ET
Research Award $750,000
Limited PCORI Funding Announcement: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results -- Cycle 3 2021
Key Dates Type Total Direct Costs
Letter of Intent (LOI): September 28, 2021 at 5pm ET
Application: December 7, 2021 at 5pm ET
Implementation Award Up to $1.5 million in total direct costs for Standard Implementation Projects, up to $4.5 million in total direct costs for Phased Implementation Projects, up to $300,000 in total costs for Dissemination Projects.
Implementation of Effective Shared Decision Making Approaches in Practice Settings -- Cycle 3 2021
Key Dates Type Total Direct Costs
Letter of Intent (LOI): September 28, 2021 by 5pm (ET)
Application: December 7, 2021 by 5pm (ET)
Implementation Award $1.5 million
Implementation of Findings from PCORI's Major Research Investments -- Cycle 3 2021
Key Dates Type Total Costs
Letter of Intent (LOI): September 28, 2021 by 5pm (ET)
Application: December 7, 2021 by 5pm (ET)
Implementation Award Up to $2.5 million
Engagement Award: Capacity Building -- October 2021 Cycle
Key Dates Type Total Costs
Letter of Intent (LOI): October 1, 2021 by 5pm (ET)
Application: By invitation only; Full proposals are due January 10, 2022 by 5 pm (ET)
Research Support Award Award total costs may not exceed $250,000 (Direct + Indirect Costs)
Engagement Award: Dissemination Initiative -- October 2021 Cycle
Key Dates Type Total Costs
Letter of Intent (LOI): October 1, 2021 by 5pm (ET)
Application: By invitation only; Full proposals are due January 10, 2022 by 5 pm (ET)
Research Support Award Award total costs may not exceed $250,000 (Direct + Indirect Costs)
Engagement Award: Stakeholder Convening Support -- October 2021 Cycle
Key Dates Type Total Costs
Letter of Intent (LOI): October 1, 2021 by 5pm (ET)
Application: By invitation only; Full proposals are due January 10, 2022 by 5 pm (ET)
Research Support Award Award total costs may not exceed $100,000 (Direct + Indirect Costs)

Upcoming Opportunities

Check back soon for information about future PCORI funding announcements.

Closed Opportunities

All Closed Funding Opportunities

Applicant and Awardee FAQs Related to COVID-19: PCORI is working to assist applicants and awardees in finding solutions that may help address issues related to disruptions associated with COVID-19, including general guidance and information about funding cycle and submission deadline changes. View the FAQs

Improving Postpartum Maternal Outcomes for Populations Experiencing Disparities -- Cycle 2 2021
Key Dates Type Total Direct Costs
Letter of Intent (LOI): June 1, 2021 at 5pm ET

Application: August 31, 2021 at 5pm ET
Research Award Up to $5 million (small studies) or $15 million (large studies)
Nonsurgical Options for Women with Urinary Incontinence -- Cycle 2 2021
Key Dates Type Total Direct Costs
Letter of Intent (LOI): June 1, 2021 at 5 pm ET

Application: August 31, 2021 at 5 pm ET
Research Award Up to $5 million
Comparative Effectiveness of Interventions Targeting Mental Health Conditions in Individuals with Intellectual and Developmental Disabilities -- Cycle 2 2021
Key Dates Type Total Direct Costs
Letter of Intent (LOI): June 1, 2021 at 5pm ET

Application: August 31, 2021 at 5 pm ET
Research Award Up to $3 million
Pragmatic Clinical Studies to Evaluate Patient-Centered Outcomes -- Cycle 2 2021
Key Dates Type Total Direct Costs
Letter of Intent (LOI): June 1, 2021 at 5pm ET

Application: August 31, 2021 at 5pm ET
Research Award $10 million
Broad PCORI Funding Announcements -- Cycle 2 2021
Key Dates Type Total Direct Costs
Letter of Intent (LOI): June 1, 2021 at 5pm ET

Application: August 31, 2021 at 5pm ET
Research Award Addressing Disparities; Assessment of Prevention, Diagnosis, and Treatment Options; and Improving Healthcare Systems: up to $3 million (Small), up to $5 million (Large); Communication and Dissemination Research: up to $2 million
Improving Methods for Conducting Patient-Centered Outcomes Research -- Cycle 2 2021
Key Dates Type Total Direct Costs
Letter of Intent (LOI): June 1, 2021 at 5pm ET

Application: August 31, 2021 at 5pm ET
Research Award $750,000
Limited PCORI Funding Announcement: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results – Cycle 2 2021
Key Dates Type Total Direct Costs
Letter of Intent (LOI): June 22, 2021 at 5pm ET

Application: August 31, 2021 at 5pm ET
Implementation Award Up to $1.5 million in total direct costs for Standard Implementation Projects, up to $4.5 million in total direct costs for Phased Implementation Projects, up to $300,000 in total costs for Dissemination Projects.
Implementation of Effective Shared Decision Making Approaches in Practice Settings -- Cycle 2 2021
Key Dates Type Total Direct Costs
Letter of Intent (LOI): June 22, 2021 at 5pm ET

Application: August 31, 2021 at 5pm ET
Implementation Award $1.5 million
Implementation of Findings from PCORI's Major Research Investments -- Cycle 2 2021
Key Dates Type Total Costs
Letter of Intent (LOI): June 22, 2021 at 5pm ET

Application: August 31, 2021 at 5pm ET
Implementation Award $2.5 million
Limited PCORI Funding Announcement: Coordinating Center Functions to Advance Phase 3 of PCORnet®, the National Patient-Centered Clinical Research Network -- Cycle 2 2021
Key Dates Type Total Costs
Letter of Intent (LOI): June 1, 2021 at 5pm ET

Application: August 10, 2021 at 5pm ET
Infrastructure Award $3.0 million - Scope 1; $5.0 million - Scope 2; $6.5 million - Scope 3; $1.5 million - Scope 4; $2.0 million - Scope 5; See PFA for further details
Engagement Award Special Cycle: Building Capacity for PCOR/CER for Topics Related to COVID-19
Key Dates Type Total Costs
Application: May 24, 2021, by 5 p.m. (ET)
Research Support Award Award total costs may not exceed $200,000 (Direct + Indirect Costs)
Engagement Award Special Cycle: Building Capacity for PCOR/CER in Intellectual and Developmental Disabilities
Key Dates Type Total Costs
Application: May 24, 2021, by 5 p.m. (ET)
Research Support Award Award total costs may not exceed $250,000 (Direct + Indirect Costs)
Increasing COVID-19 Vaccine Confidence among Long-Term Care Workers: Expedited COVID-19 Targeted PCORI Funding Announcement -- Cycle 2 2021
Key Dates Type Total Direct Costs
Application: May 4, 2021 at 5pm ET
Research Award Up to $5,000,000
Pragmatic Clinical Studies to Evaluate Patient-Centered Outcomes -- Cycle 1 2021
Key Dates Type Total Direct Costs
Letter of Intent (LOI): February 2, 2021 at 5pm ET

Application: May 4, 2021 at 5pm ET
Research Award $10 million
Broad PCORI Funding Announcements -- Cycle 1 2021
Key Dates Type Total Direct Costs
Letter of Intent (LOI): February 2, 2021 at 5pm ET

Application: May 4, 2021 at 5pm ET
Research Award Addressing Disparities; Assessment of Prevention, Diagnosis, and Treatment Options; and Improving Healthcare Systems: up to $3 million (Small) - up to $5 million (Large) — Communication & Dissemination Research: up to $2 million
Improving Methods for Conducting Patient-Centered Outcomes Research -- Cycle 1 2021
Key Dates Type Total Direct Costs
Letter of Intent (LOI): February 2, 2021 at 5pm ET

Application: May 4, 2021 at 5pm ET
Research Award $750,000
Optimizing Infrastructure for Conducting Patient-Centered Outcomes Research: PCORnet, The National Patient-Centered Clinical Research Network -- Phase 3 -- Cycle 1 2021
Key Dates Type Total Costs
Application: April 6, 2021 at 5pm ET
Infrastructure Award $6.5 million for CRNs with up to 7 data contributing sites; $7.5 million for CRNs with greater than 7 data contributing sites
Limited PCORI Funding Announcement: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results – Cycle 1 2021
Key Dates Type Total Direct Costs
Letter of Intent (LOI): January 26, 2021 at 5pm ET

Application: April 6, 2021 at 5pm ET
Implementation Award Up to $1.5 million in total direct costs for Standard Implementation Projects, up to $4.5 million in total direct costs for Phased Implementation Projects, up to $300,000 in total costs for Dissemination Projects.
Engagement Award: Capacity Building -- April 2021 Cycle
Key Dates Type Total Costs
Letter of Intent (LOI): April 1, 2021, by 5 p.m. (ET)

Application: By invitation only; Full proposals are due July 12, 2021, by 5 pm (ET)
Research Support Award Award total costs may not exceed $250,000 (Direct + Indirect Costs)
Engagement Award: Dissemination Initiative -- April 2021 Cycle
Key Dates Type Total Costs
Letter of Intent (LOI): April 1, 2021, by 5 p.m. (ET)

Application: By invitation only; Full proposals are due July 12, 2021, by 5 pm (ET)
Research Support Award Award total costs may not exceed $250,000 (Direct + Indirect Costs)
Engagement Award: Stakeholder Convening Support -- April 2021 Cycle
Key Dates Type Total Costs
Letter of Intent (LOI): April 1, 2021, by 5 p.m. (ET)

Application: By invitation only; Full proposals are due July 12, 2021, by 5 pm (ET)
Research Support Award Award total costs may not exceed $100,000 (Direct + Indirect Costs)
Engagement Award: Capacity Building -- October 2020 Cycle
Key Dates Type Total Costs
Letter of Inquiry (LOI): October 1, 2020, by 5 p.m. (ET)

Application: By invitation only; Full proposals are due January 11, 2021, by 5 p.m. (ET)
Research Support Award Award total costs may not exceed $250,000 (Direct + Indirect)
Engagement Award: Dissemination Initiative -- October 2020 Cycle
Key Dates Type Total Costs
Letter of Inquiry (LOI): October 1, 2020, by 5 p.m. (ET)

Application: By invitation only; Full proposals are due January 11, 2021, by 5 p.m. (ET)
Research Support Award Award total costs may not exceed $250,000 (Direct + Indirect)
Engagement Award: Stakeholder Convening Support -- October 2020 Cycle
Key Dates Type Total Costs
Letter of Inquiry (LOI): October 1, 2020, by 5 p.m. (ET)

Application: By invitation only; Full proposals are due January 11, 2021, by 5 p.m. (ET)
Research Support Award Award total costs may not exceed $100,000 (Direct + Indirect)
Phased Large Awards for Comparative Effectiveness Research – Cycle 3 2020
Key Dates Type Total Direct Costs
Application: January 12, 2021 at 5pm ET
Research Award $22 million (Feasibility phase: $2 million; Full-scale study phase: $20 million)
Suicide Prevention: Brief Interventions for Youth -- Cycle 3 2020
Key Dates Type Total Direct Costs
Letter of Intent (LOI): September 29, 2020 at 5pm ET

Application: January 12, 2021 at 5pm ET
Research Award Up to $10 million
Broad PCORI Funding Announcements – Cycle 3 2020 (for Addressing Disparities, Assessment of Options, Communication and Dissemination Research, Improving Healthcare Systems)
Key Dates Type Total Direct Costs
Letter of Intent (LOI): September 29, 2020 at 5pm ET

Application: January 12, 2021 at 5pm ET
Research Award Addressing Disparities; Assessment of Prevention, Diagnosis, and Treatment Options; and Improving Healthcare Systems: up to $3 million (Small) - up to $5 million (Large) — Communication & Dissemination Research: up to $2 million
Improving Methods for Conducting Patient-Centered Outcomes Research -- Cycle 3 2020
Key Dates Type Total Direct Costs
Letter of Intent (LOI): September 29, 2020 by 5pm ET

Application: January 12, 2021 by 5pm ET
Research Award See PFA for details
Implementation of Findings from PCORI's Major Research Investments -- Cycle 3 2020
Key Dates Type Total Costs
Letter of Intent (LOI): September 22, 2020 at 5pm ET

Application: December 1, 2020 at 5pm ET
Implementation Award Up to $2.5 million
Limited PCORI Funding Announcement: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results – Cycle 3 2020
Key Dates Type Total Direct Costs
Letter of Intent (LOI): September 22, 2020 at 5pm ET

Application: December 1, 2020 at 5pm ET
Implementation Award Up to $1 million (see relevant section of the PFA for more information)
Limited Competition PCORI Funding Announcement: Conducting Rare Disease Research using PCORnet® – Cycle 2 2020
Key Dates Type Total Direct Costs
Application: September 1, 2020 at 5pm ET
Research Award $3.5 million
Observational Analyses of Second-Line Pharmacological Agents in Type 2 Diabetes – Cycle 2 2020
Key Dates Type Total Direct Costs
Application: September 1, 2020 at 5pm ET
Research Award Up to $4 million
Implementation of Effective Shared Decision Making Approaches in Practice Settings – Cycle 2 2020
Key Dates Type Total Direct Costs
Application: August 31, 2020 at 5pm ET
Implementation Award $1.5 million
Limited PCORI Funding Announcement: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results – Cycle 2 2020
Key Dates Type Total Direct Costs
Application: August 31, 2020 at 5pm ET
Implementation Award Up to $1 million (see relevant section of the PFA for more information)
PCORI Funding Opportunity for COVID-19-Related Enhancements to Existing PCORI-Funded Research Projects
Key Dates Type Total Costs
Application: Friday, July 17, 2020; 5:00 p.m. ET
Research Award $500,000 limit (direct and indirect costs)—higher amounts will be considered on a case-by-case basis, based on applicants’ justification of the proposed amount.
PCORI Funding Opportunity for COVID-19-Related Enhancements to Existing PCORI-Funded Engagement Awards
Key Dates Type Total Costs
Application: Friday, July 17, 2020; 5:00 p.m. ET
Research Support Award Engagement Award Enhancements may not exceed $150,000 (direct and indirect costs)
PCORI Funding Opportunity for COVID-19-Related Enhancements to Existing PCORI-Funded Dissemination and Implementation Awards
Key Dates Type Total Costs
Application: Friday, July 17, 2020; 5:00 p.m. ET
Implementation Award $500,000 limit (direct and indirect costs) for Dissemination and Implementation Project Award Enhancements— higher amounts will be considered on a case-by-case basis, based on applicant's justification of the proposed amount.
COVID-19 Targeted PFA
Key Dates Type Total Costs
Application: May 26, 2020 at 5pm ET
Research Award Small Studies: up to $2,500,000 — Large Studies: up to $5,000,000
Engagement Award Special Cycle: Supporting Engagement in and Dissemination of PCOR/CER in the Context of COVID-19
Key Dates Type Total Costs
Application: May 22, 2020, by 5 p.m. (ET)
Research Support Award Award total costs may not exceed $150,000
Broad PCORI Funding Announcements -- Cycle 1 2020 (for Addressing Disparities, Assessment of Options, Communication and Dissemination Research, Improving Healthcare Systems)
Key Dates Type Total Direct Costs
Letter of Intent (LOI): February 4, 2020 by 5 p.m. (ET)

Application: May 5, 2020 by 5 p.m. (ET)
Research Award Addressing Disparities; Assessment of Prevention, Diagnosis, and Treatment Options; Improving Healthcare Systems: $3 million for small studies; $5 million for large studies • Communication and Dissemination Research: $2 million
Improving Methods for Conducting Patient-Centered Outcomes Research -- Cycle 1 2020
Key Dates Type Total Direct Costs
Letter of Intent (LOI): February 4, 2020 by 5 p.m. (ET)

Application: May 5, 2020 by 5 p.m. (ET)
Research Award $750,000
Limited PCORI Funding Announcement: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results -- Cycle 1 2020
Key Dates Type Total Direct Costs
Letter of Intent (LOI): January 28, 2020 by 5 p.m. (ET)

Application: April 7, 2020 by 5 p.m. (ET)
Implementation Award Up to $1 million (see relevant section of the PFA for more information)
Engagement Award: Capacity Building -- May 2020 Cycle
Key Dates Type Total Costs
Letter of Inquiry (LOI): May 1, 2020, by 5 p.m. (ET)

Application: By invitation only; Full proposals are due 40 calendar days after LOI approval and invitation
Research Support Award Award total costs may not exceed $250,000
Engagement Award: Dissemination Initiative -- May 2020 Cycle
Key Dates Type Total Costs
Letter of Inquiry (LOI): May 1, 2020, by 5 p.m. (ET)

Application: By invitation only; Full proposals are due 40 calendar days after LOI approval and invitation
Research Support Award Award total costs may not exceed $250,000
Engagement Award: Stakeholder Convening Support -- May 2020 Cycle
Key Dates Type Total Costs
Letter of Inquiry (LOI): May 1, 2020, by 5 p.m. (ET)

Application: By invitation only; Full proposals are due 40 calendar days after LOI approval and invitation
Research Support Award Award total costs may not exceed $100,000
Broad PCORI Funding Announcements -- Cycle 3 2019 (for Addressing Disparities, Assessment of Options, Communication and Dissemination Research, Improving Healthcare Systems)
Key Dates Type Total Direct Costs
Letter of Intent (LOI): October 1, 2019 by 5 p.m. (ET)

Application: January 14, 2020 by 5 p.m. (ET)
Research Award Addressing Disparities; Assessment of Prevention, Diagnosis, and Treatment Options; and Improving Healthcare Systems: $3 million; Communication & Dissemination Research: $2 million
Improving Methods for Conducting Patient-Centered Outcomes Research -- Cycle 3 2019
Key Dates Type Total Direct Costs
Letter of Intent (LOI): October 1, 2019 by 5 p.m. (ET)

Application: January 14, 2020 by 5 p.m. (ET)
Research Award $750,000
Limited PCORI Funding Announcement: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results -- Cycle 3 2019
Key Dates Type Total Direct Costs
Letter of Intent (LOI): September 24, 2019 by 5 p.m. (ET)

Application: December 3, 2019 by 5 p.m. (ET)
Implementation Award Up to $1 million (see relevant section of the PFA for more information)
Research-Related Conference Support for Planning of Individual Participant-Level Data Meta-Analysis (RRCS-IPD MA)
Key Dates Type Total Costs
Application: Reviews to be conducted on a rolling basis, as program funds allow
Research Support Award Award total costs must not exceed $50,000
Engagement Award: Accelerating the Adoption of Tools & Resources
Key Dates Type Total Costs
Letter of Inquiry (LOI): November 15, 2019 by 5 p.m. (ET)

Application: Full proposals are due 40 days after review and approval of the LOI.
Research Support Award Award total costs may not exceed $100,000
Engagement Award: Community Convening Around Patient-Centered Outcomes Research (PCOR)
Key Dates Type Total Costs
Letter of Inquiry (LOI): November 15, 2019 by 5 p.m. (ET)

Application: Full proposals are due 40 days after review and approval of the LOI.
Research Support Award Award total costs may not exceed $100,000
Treatment Options for Age-Related Hearing Loss -- Cycle 2 2019
Key Dates Type Total Direct Costs
Letter of Intent (LOI): May 29, 2019 by 5 p.m. (ET)

Application: September 4, 2019 by 5 p.m. (ET)
Research Award $2 million
Broad PCORI Funding Announcements -- Cycle 2 2019 (for Addressing Disparities, Assessment of Options, Communication and Dissemination Research, Improving Healthcare Systems)
Key Dates Type Total Direct Costs
Letter of Intent (LOI): May 29, 2019 by 5 p.m. (ET)

Application: September 4, 2019 by 5 p.m. (ET)
Research Award Addressing Disparities; Assessment of Prevention, Diagnosis, and Treatment Options; and Improving Healthcare Systems: $3 million; Communication & Dissemination Research: $2 million
Improving Methods for Conducting Patient-Centered Outcomes Research -- Cycle 2 2019
Key Dates Type Total Direct Costs
Letter of Intent (LOI): May 29, 2019 by 5 p.m. (ET)

Application: September 4, 2019 by 5 p.m. (ET)
Research Award $750,000
Limited PCORI Funding Announcement: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results -- Cycle 2 2019
Key Dates Type Total Direct Costs
Letter of Intent (LOI): June 19, 2019 by 5 p.m. (ET)

Application: August 30, 2019 by 5 p.m. (ET)
Implementation Award Up to $1 million (see relevant section of the PFA for more information)
Implementation of Effective Shared Decision Making Approaches in Practice Settings -- Cycle 2 2019
Key Dates Type Total Direct Costs
Letter of Intent (LOI): June 19, 2019 by 5 p.m. (ET)

Application: August 30, 2019 by 5 p.m. (ET)
Implementation Award $1.5 million
Engagement Award: Conference Support
Key Dates Type Total Costs
Letter of Inquiry (LOI): A Letter of Inquiry is not required.

Application: To be announced.
Research Support Award Award total costs must not exceed $50,000
Treatment of Posttraumatic Stress Disorder (PTSD) in Adults -- Cycle 1 2019
Key Dates Type Total Direct Costs
Letter of Intent (LOI): January 31, 2019 by 5 p.m. (ET)

Application: April 24, 2019 by 5 p.m. (ET)
Research Award $5 million
Treatment Options for Age-Related Hearing Loss -- Cycle 1 2019
Key Dates Type Total Direct Costs
Letter of Intent (LOI): January 31, 2019 by 5 p.m. (ET)

Application: April 24, 2019 by 5 p.m. (ET)
Research Award $2 million
Treatment of Anxiety in Children, Adolescents, and/or Young Adults -- Cycle 1 2019
Key Dates Type Total Direct Costs
Letter of Intent (LOI): January 31, 2019 by 5 p.m. (ET)

Application: April 24, 2019 by 5 p.m. (ET)
Research Award $5 million
Limited PCORI Funding Announcement: Partnerships to Conduct Research within PCORnet (PaCR) -- Cycle 1 2019
Key Dates Type Total Direct Costs
Letter of Intent (LOI): May 13, 2019 by 5 p.m. (ET)

Application: July 25, 2019 by 5 p.m. (ET)
Research Award $2 million
Broad PCORI Funding Announcements -- Cycle 1 2019 (for Addressing Disparities, Assessment of Options, Communication and Dissemination Research, Improving Healthcare Systems)
Key Dates Type Total Direct Costs
Letter of Intent (LOI): January 31, 2019 by 5 p.m. (ET)

Application: April 24, 2019 by 5 p.m. (ET)
Research Award See PFA for details
Improving Methods for Conducting Patient-Centered Outcomes Research -- Cycle 1 2019
Key Dates Type Total Direct Costs
Letter of Intent (LOI): January 31, 2019 by 5 p.m. (ET)

Application: April 24, 2019 by 5 p.m. (ET)
Research Award See PFA for details
Implementation of Findings from PCORI's Major Research Investments -- Cycle 1 2019
Key Dates Type Total Costs
Letter of Intent (LOI): January 24, 2019 by 5 p.m. (ET)

Application: April 4, 2019 by 5 p.m. (ET)
Implementation Award Up to $2.5 million
Limited PCORI Funding Announcement: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results -- Cycle 1 2019
Key Dates Type Total Direct Costs
Letter of Intent (LOI): January 24, 2019 by 5 p.m. (ET)

Application: April 4, 2019 by 5 p.m. (ET)
Implementation Award Up to $1 million (see relevant section of the PFA for more information)
Broad PCORI Funding Announcements -- Cycle 3 2018 (for Addressing Disparities, Assessment of Prevention, Diagnosis, and Treatment Options, Communication and Dissemination Research, and Improving Healthcare Systems)
Key Dates Type Total Direct Costs
Letter of Intent (LOI): November 6, 2018 by 5 p.m. (ET)

Application: February 12, 2019 by 5 p.m. (ET)
Research Award $3 million (AD, APDTO, IHS); $2 million (CDR)
Improving Methods for Conducting Patient-Centered Outcomes Research -- Cycle 3 2018
Key Dates Type Total Direct Costs
Letter of Intent (LOI): November 6, 2018 by 5 p.m. (ET)

Application: February 12, 2019 by 5 p.m. (ET)
Research Award $750,000
Limited PCORI Funding Announcement: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results -- Cycle 3 2018
Key Dates Type Total Direct Costs
Letter of Intent (LOI): November 6, 2018 by 5 p.m. (ET)

Application: January 16, 2019 by 5 p.m. (ET)
Implementation Award Up to $1 million with clear and adequate justification (see relevant section of the PFA for more information)
PPRN Limited Competition Award*
Key Dates Type Total Costs
Application: December 18, 2018, by 5 pm (ET)
Research Support Award Award total costs may not exceed $350,000
Psychosocial Interventions with Office-Based Opioid Treatment for Opioid Use Disorder -- Cycle 2 2018
Key Dates Type Total Direct Costs
Letter of Intent (LOI): June 28, 2018 by 5 p.m. (ET)

Application: September 25, 2018 by 5 p.m. (ET)
Research Award $4 million
Symptom Management for Patients with Advanced Illness -- Cycle 2 2018
Key Dates Type Total Direct Costs
Letter of Intent (LOI): June 28, 2018 by 5 p.m. (ET)

Application: September 25, 2018 by 5 p.m. (ET)
Research Award $2 million
Improving Methods for Conducting Patient-Centered Outcomes Research -- Cycle 2 2018
Key Dates Type Total Direct Costs
Letter of Intent (LOI): June 28, 2018 by 5 p.m. (ET)

Application: September 25, 2018 by 5 p.m. (ET)
Research Award $750,000
Medication-Assisted Treatment (MAT) Delivery for Pregnant Women with Substance Use Disorders Involving Prescription Opioids and/or Heroin -- Cycle 2 2018
Key Dates Type Total Direct Costs
Letter of Intent (LOI): June 28, 2018 by 5 p.m. (ET)

Application: September 25, 2018 by 5 p.m. (ET)
Research Award $4 million
Broad PCORI Funding Announcements -- Cycle 2 2018 (for Addressing Disparities, Assessment of Options, Communication and Dissemination Research, Improving Healthcare Systems)
Key Dates Type Total Direct Costs
Letter of Intent (LOI): June 28, 2018 by 5 p.m. (ET)

Application: September 25, 2018 by 5 p.m. (ET)
Research Award See PFA description for details
Limited PCORI Funding Announcement: Implementation of PCORI-Funded Patient-Centered Outcomes Research Results -- Cycle 2 2018
Key Dates Type Total Direct Costs
Letter of Intent (LOI): June 21, 2018 by 5 p.m. (ET)

Application: August 30, 2018 by 5 p.m. (ET)
Implementation Award Up to $1 million with clear and adequate justification (see relevant section of the PFA for more information)
PCORI Funding Announcement: Implementation of Effective Shared Decision Making Approaches in Practice Settings -- Cycle 2 2018
Key Dates Type Total Direct Costs
Letter of Intent (LOI): July 24, 2018 by 5 p.m. (ET)

Application: October 10, 2018 by 5 p.m. (ET)
Implementation Award $1.5 million
Pharmacological Treatment for Anxiety Disorders in Children, Adolescents, and/or Young Adults - Cycle 1 2018
Key Dates Type Total Direct Costs
Letter of Intent (LOI): February 13, 2018 by 5 p.m. (ET)

Application: May 16, 2018 by 5 p.m. (ET)
Research Award $15 million
Pragmatic Clinical Studies to Evaluate Patient-Centered Outcomes - Cycle 1 2018
Key Dates Type Total Direct Costs
Letter of Intent (LOI): February 13, 2018 by 5 p.m. (ET)

Application: May 16, 2018 by 5 p.m. (ET)
Research Award $10 million
Improving Methods for Conducting PCOR - Cycle 1 2018
Key Dates Type Total Direct Costs
Letter of Intent (LOI): February 13, 2018 by 5 p.m. (ET)

Application: May 16, 2018 by 5 p.m. (ET)
Research Award $750,000
Limited PCORI Funding Announcement: Dissemination and Implementation of PCORI-Funded Patient-Centered Outcomes Research Results - Cycle 1 2018
Key Dates Type Total Direct Costs
Letter of Intent (LOI): February 13, 2018 by 5 p.m. (ET)

Application: May 16, 2018 by 5 p.m. (ET)
Implementation Award Up to $1 million with clear and adequate justification (see relevant section of the PFA for more information)
Broad PCORI Funding Announcements - Cycle 1 2018 (for Addressing Disparities, Assessment of Options, Communication and Dissemination Research, Improving Healthcare Systems)
Key Dates Type Total Direct Costs
Letter of Intent (LOI): February 13, 2018 by 5 p.m. (ET)

Application: May 16, 2018 by 5 p.m. (ET)
Research Award See PFA for details
Pragmatic Clinical Studies to Evaluate Patient-Centered Outcomes - Cycle 3 2017
Key Dates Type Total Direct Costs
Letter of Intent (LOI): October 31, 2017 by 5 p.m. (ET)

Application: February 6, 2018 by 5 p.m. (ET)
Research Award $10 million
Broad PCORI Funding Announcements - Cycle 3 2017 (for Addressing Disparities, Assessment of Options, Communication and Dissemination Research, Improving Healthcare Systems)
Key Dates Type Total Direct Costs
Application: February 6, 2018 by 5 p.m. (ET)
Research Award See PFA for details
Improving Methods for Conducting PCOR - Cycle 3 2017
Key Dates Type Total Direct Costs
Letter of Intent (LOI): October 31, 2017 by 5 p.m. (ET)

Application: February 6, 2018 by 5 p.m. (ET)
Research Award $750,000
Limited PCORI Funding Announcement: Dissemination and Implementation of PCORI-Funded Patient-Centered Outcomes Research Results - Cycle 3 2017
Key Dates Type Total Direct Costs
Letter of Intent (LOI): October 31, 2017 by 5 p.m. (ET)

Application: February 6, 2018 by 5 p.m. (ET)
Research Award $350,000
Request for Applications: Atrial Fibrillation Strategically Focused Research Network
Key Dates Type Total Costs
Application: January 31, 2018 by 5 p.m. (CT)
Research Award
Pragmatic Clinical Studies to Evaluate Patient-Centered Outcomes - Cycle 2 2017
Key Dates Type Total Direct Costs
Letter of Intent (LOI): July 25, 2017 by 5 p.m. (ET)

Application: October 25, 2017 by 5 p.m. (ET)
Research Award $10 million
Medication-Assisted Treatment (MAT) Delivery for Pregnant Women with Substance Use Disorders Involving Prescription Opioids and/or Heroin - Cycle 2 2017
Key Dates Type Total Direct Costs
Letter of Intent (LOI): July 25, 2017 by 5 p.m. (ET)

Application: October 25, 2017 by 5 p.m. (ET)
Research Award $4 million
Symptom Management for Patients with Advanced Illness - Cycle 2 2017
Key Dates Type Total Direct Costs
Letter of Intent (LOI): July 25, 2017 by 5 p.m. (ET)

Application: October 25, 2017 by 5 p.m. (ET)
Research Award $2 million
Limited PCORI Funding Announcement: Dissemination and Implementation of PCORI-Funded Patient-Centered Outcomes Research Results - Cycle 2 2017
Key Dates Type Total Direct Costs
Letter of Intent (LOI): July 25, 2017 by 5 p.m. (ET)

Application: October 25, 2017 by 5 p.m. (ET)
Research Award $350,000
Limited PCORI Funding Announcement: Partnerships to Conduct Research within PCORnet (PaCR) - Cycle 2 2017
Key Dates Type Total Direct Costs
Letter of Intent (LOI): September 6, 2017 by 5 p.m. (ET)

Application: December 6, 2017 by 5 p.m. (ET)
Research Award $5 million
Strategies to Prevent Unsafe Opioid Prescribing in Primary Care among Patients with Acute or Chronic Noncancer Pain
Key Dates Type Total Costs
Application: January 10, 2018 by 5 p.m. (ET)
Research Award $5 million
PCORI Funding Announcement: Implementation of Effective Shared Decision Making Approaches in Practice Settings - Cycle 2 2017
Key Dates Type Total Direct Costs
Letter of Intent (LOI): October 2, 2017 by 5 p.m. (ET)

Application: January 10, 2018 by 5 p.m. (ET)
Implementation Award $1.5 million
Pragmatic Clinical Studies to Evaluate Patient-Centered Outcomes - Cycle 1 2017
Key Dates Type Total Direct Costs
Letter of Intent (LOI): February 14th, 2017

Application: May 17, 2017
Research Award $10 million
Comparison of Surgical and Nonsurgical Options for Management of Chronic Nonspecific Low Back Pain - Cycle 1 2017
Key Dates Type Total Direct Costs
Letter of Intent (LOI):

Application: May 17, 2017
Research Award $15 million
Optimized Multidisciplinary Treatment Programs for Nonspecific Chronic Low Back Pain – Cycle 1 2017
Key Dates Type Total Direct Costs
Letter of Intent (LOI):

Application: May 17, 2017
Research Award $10 million
Improving Methods for Conducting PCOR - Cycle 1 2017
Key Dates Type Total Direct Costs
Letter of Intent (LOI):

Application: May 17, 2017
Research Award $750,000
Broad PCORI Funding Announcements - Cycle 1 2017
Key Dates Type Total Direct Costs
Application: May 17th, 2017 by 5 p.m. (ET)
Research Award See specific PFA for details
Limited PCORI Funding Announcement: Dissemination and Implementation of PCORI-Funded Patient-Centered Outcomes Research Results - Cycle 1 2017
Key Dates Type Total Direct Costs
Letter of Intent (LOI):

Application: May 17, 2017
Implementation Award $350,000
Pragmatic Clinical Studies to Evaluate Patient-Centered Outcomes - Cycle 3 2016
Key Dates Type Total Direct Costs
Letter of Intent (LOI):

Application: December 19, 2016
Research Award $10 million
Treatment of Multiple Sclerosis - Cycle 3 2016
Key Dates Type Total Direct Costs
Letter of Intent (LOI):

Application: February 7, 2017
Research Award Question 1 - $10 million; Question 2 - $3 million; Question 3 - $5 million
Clinical Strategies for Managing and Reducing Long-Term Opioid Use for Chronic Pain – Cycle 3 2016
Key Dates Type Total Direct Costs
Letter of Intent (LOI):

Application: February 7, 2017
Research Award $10 million
Community-Based Palliative Care Delivery for Adult Patients with Advanced Illnesses and their Caregivers - Cycle 3 2016
Key Dates Type Total Direct Costs
Letter of Intent (LOI):

Application: December 19, 2016
Research Award • Advance Care Planning: Not to exceed $6M per study • Models of Palliative Care Delivery: Not to exceed $10M per study
Strategies to Prevent Unsafe Opioid Prescribing in Primary Care among Patients with Acute or Chronic Non-Cancer Pain - Cycle 3 2016
Key Dates Type Total Costs
Letter of Intent (LOI):

Application: December 19, 2016
Research Award $5 Million
Management of Care Transitions for Emerging Adults with Sickle Cell Disease
Key Dates Type Total Costs
Letter of Intent (LOI):

Application: December 19, 2016
Research Award $8.33 million
Assessment of Prevention, Diagnosis, and Treatment Options - Cycle 3 2016
Key Dates Type Total Direct Costs
Letter of Intent (LOI):

Application: December 19, 2016
Research Award $2 million
Improving Healthcare Systems - Cycle 3 2016
Key Dates Type Total Direct Costs
Letter of Intent (LOI):

Application: December 19, 2016
Research Award $5 million for large studies, $1.5 million for small studies
Communication and Dissemination Research - Cycle 3 2016
Key Dates Type Total Direct Costs
Letter of Intent (LOI):

Application: December 19, 2016
Research Award $1.5 million
Improving Methods for Conducting Patient-Centered Outcomes Research - Cycle 3 2016
Key Dates Type Total Direct Costs
Letter of Intent (LOI):

Application: December 19, 2016
Research Award $750,000
Addressing Disparities - Cycle 3 2016
Key Dates Type Total Direct Costs
Letter of Intent (LOI):

Application: December 19, 2016
Research Award $1.5 million
Limited PCORI Funding Announcement: Dissemination and Implementation of PCORI-Funded Patient-Centered Outcomes Research Results and Products in Real World Settings - Cycle 3 2016
Key Dates Type Total Direct Costs
Letter of Intent (LOI):

Application: December 19, 2016
Research Award $300,000
Pragmatic Clinical Studies to Evaluate Patient-Centered Outcomes - Cycle 2 2016
Key Dates Type Total Direct Costs
Letter of Intent (LOI):

Application: August 8, 2016
Research Award $10 million
Comparison of Surgical and Nonsurgical Options for Management of Nonspecific Chronic Low Back Pain - Cycle 2 2016
Key Dates Type Total Direct Costs
Letter of Intent (LOI):

Application: August 8, 2016
Research Award $15 million
Patient-Centered Outcomes Research (PCOR) for Treatment Options in Uterine Fibroids: Developing a Prospective Multi-Center Practice-based Clinical Registry (P50)
Key Dates Type Total Costs
Letter of Intent (LOI):

Application: December 16, 2013
Research Award Up to $4 million total costs/year (MAXIMUM BUDGET)
Pipeline to Proposal Awards Tier A Pre-Engagement/Community Projects
Key Dates Type Total Costs
Letter of Intent (LOI):

Application: June 30, 2017
Research Support Award
Pipeline to Proposal Awards Tier I Cycle 2 - Pre-Engagement/Community Projects
Key Dates Type Total Costs
Letter of Intent (LOI):

Application: February 20, 2015, 5pm ET
Research Support Award
Pipeline to Proposal Awards Tier I Cycle 3 - Pre-Engagement/Community Projects
Key Dates Type Total Costs
Letter of Intent (LOI):

Application: April 18, 2016 by 11:59 p.m. ET
Research Support Award
Pipeline to Proposal Awards Independent Tier III – Proposal Development Projects
Key Dates Type Total Costs
Application: September 30, 2016
Research Support Award