PCORI is seeking applications to study the comparative clinical effectiveness of alternative features of healthcare systems (e.g., innovative technologies, incentive structures, and service designs) that are intended to optimize the quality, outcomes, and efficiency of care for patients and that have the most potential for sustained impact and replication within and across healthcare systems. Healthcare systems encompass multiple levels (e.g., national, state, and local health environments; organization or practice settings; family and social supports; and the individual patient) and include entities organized to deliver, arrange, purchase, or coordinate healthcare services. PCORI seeks to fund studies that will provide information of value to patients, their caregivers, clinicians, and healthcare leaders concerning which features of delivery systems lead to better patient-centered outcomes (PCOs), so that those features proven to make a difference ultimately affect healthcare delivery.

Download Full Announcement

Key Dates

Online System Opens
August 15, 2016, 12:00 AM
Letter of Intent Deadline
September 14, 2016, 12:00 AM
Awards Announced
<p><a href="/node/7940">August 15, 2017; 12:00 p.m. (ET)</a></p>

Funds and Project Period

Funds Available Up To

$16 million

Total Direct Costs

$5 million for large studies, $1.5 million for small studies

Maximum Project Period

5 years for large studies, 3 years for small studies

Applicant Resources


Award Types