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PCORI

Patient-Centered Outcomes Research Institute

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    Fact Sheets: Learn More About PCORI

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    Engagement Tools and Resources for Research

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    PCORI Funding Opportunities

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    PCORI 2021 and Beyond

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    Board Approves Future PFA Topics at April Meeting

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  • Funding Opportunities
  • Improving Postpartum Maternal Outcome...

Improving Postpartum Maternal Outcomes for Populations Experiencing Disparities -- Cycle 2 2021

This PCORI Funding Announcement will open on Tuesday, May 4, 2021, with more information about the funding opportunity.


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Notice of Upcoming PCORI Funding Announcement

The Patient-Centered Outcomes Research Institute (PCORI) plans to release a Targeted PCORI Funding Announcement on May 4, 2021, seeking to fund large randomized controlled trials (RCTs) and/or well-designed observational studies comparing multicomponent strategies to improve early detection of, and timely care for, complications up to six weeks postpartum for groups more often underserved or experiencing the greatest disparities in health outcomes, including Black, American Indian/Alaska Native (AI/AN), Hispanic, rural, and low socioeconomic status (SES) populations. This preannouncement is provided to allow potential applicants additional time to identify collaborators; obtain stakeholder input on potential studies; and develop responsive, high-quality proposals.

The United States ranks lowest among high income countries in parameters for maternal health, and 40 percent of US maternal mortality occurs during the first six weeks following delivery. Significant disparities for maternal outcomes have been reported for Black, AI/AN, Hispanic, rural, and low SES women. Although evidence-based treatments and care protocols exist for the prevention of postpartum severe maternal morbidity and mortality, postpartum care is typically limited, and there is evidence that important warning signs may be missed or dismissed by patients, as well as clinicians and systems. Signs or symptoms may overlap with those of other conditions and with those of recovery from delivery. Patients and primary or emergency care clinicians also may be unaware of the importance of recent pregnancy status for the interpretation of some symptoms and may not discuss it, and patients experiencing complications in the hospital may not receive referrals to appropriate specialty care. In addition, systemic racism and bias (conscious and unconscious), affect access to and quality of care, and significant inequities persist in access to and availability of timely, appropriate, and respectful postpartum care.

Various strategies to improve postpartum care and outcomes and eliminate disparities and advance health equity have been recommended and/or implemented by professional organizations, health systems and clinicians. Such strategies may be designed to increase awareness and detection of postpartum complications by patients and clinicians, and/or to improve structural competence and overcome bias and inequities in postpartum care.

This Targeted PCORI Funding Announcement will solicit applications that respond to the following question:

What is the comparative effectiveness of multicomponent interventions to improve early detection of, and timely care for, risk factors for postpartum complications, and for complications during the first six weeks postpartum for Black, AI/AN, Hispanic, rural, and low SES patients?

PCORI is particularly interested in the comparative effectiveness of tailored approaches to intervention strategies. Applicants should consider the following outcome categories: maternal mortality and morbidity; healthcare utilization; condition-specific outcomes; and patient experience, satisfaction, and engagement with care up to one year postpartum. Interventions must be evidence-based and/or in widespread use and reproducible.

Key Information
Status 
Upcoming
Cycle 
Cycle 2 2021
Online System Opens 
May 4, 2021
Letter of Intent (LOI) Deadline
June 1, 2021 at 5pm ET
Application Deadline
August 31, 2021 at 5pm ET
Merit Review 
December 2021
Awards Announced 
March 2022
Applicant Town Hall Session 

May 13, 2021; 12:00p.m. (ET)

Earliest Start Date 
August 2022
Total Direct Costs 
Up to $5 million (small studies) or $15 million (large studies)
Funds Available Up To 
$50 million
Maximum Project Period 
5 years
Announcement Type 
Research Award

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Research & Results

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Engagement

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  • Engage with Us

Funding Opportunities

  • What & Who We Fund
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  • Help Center

Meetings & Events

April 27
Priorities on the Health Horizon: Informing PCORI's Strategic Plan (Webinar #2)
May 6
Advisory Panel on Healthcare Delivery and Disparities Research Spring 2021 Meeting
May 10
Cycle 2 2021 Nonsurgical Options for Women with Urinary Incontinence -- Applicant Town Hall

PCORI

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Patient-Centered Outcomes
Research Institute

1828 L Street, NW, Suite 900
Washington, DC 20036
Phone: (202) 827-7700 | Fax: (202) 355-9558
info@pcori.org

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