The intent of this limited-competition PCORI Funding Announcement (PFA) is to move evidence developed with PCORI-funded research toward practical use in improving health care and health outcomes.

PCORI will fund projects that aim to implement patient-centered comparative clinical effectiveness research (CER) results obtained from PCORI-funded research in real-world practice settings, and, in selected cases, projects that focus on the dissemination of these findings.

Applicants will have the opportunity to propose*:

  1. Implementation Projects
    Implementation Projects may have budgets up to $2.5M in total direct costs and total project durations of up to 36 months.
  2. Dissemination Projects
    While this funding opportunity is designed primarily to support implementation projects, PCORI will consider supporting dissemination projects with the primary goal of spreading knowledge and awareness of evidence from PCORI-funded research and increasing targeted end-users’ motivation and ability to use it. Dissemination Projects may have budgets of up to $300,000 in total costs and total project durations of up to 36 months.

Applicant Eligibility: Recipients of PCORI-funded research awards, including Broad PCORI awards, Pilot Projects Program awards, Targeted PCORI awards, Pragmatic Clinical Study awards, and PCORI-funded demonstration projects occurring within PCORnet®, the National Patient-Centered Clinical Research Network infrastructure (e.g., ADAPTABLE and obesity trials), are eligible to respond to this PFA. Additionally:

  • Applicants proposing Implementation Projects must have a draft final research report (DFRR) pertaining to the original PCORI-funded research award accepted for entry into PCORI’s peer-review process by the Letter of Intent (LOI) deadline.

*Previous issuances of this PFA included an opportunity for Phased Implementation Projects. The Phased Implementation opportunity is unavailable for this cycle. Updates to future cycles will be announced no later than four weeks before the cycle open date.

Download Full Announcement

Key Dates

Online System Opens
May 2, 2023
Letter of Intent Deadline
May 31, 2023; 5:00 pm ET
Letter of Intent Status Notification
June 27, 2023
Application Deadline
August 29, 2023; 5:00 pm ET
Merit Review
November 2023
Awards Announced
April 2024
Earliest Start Date
July 2024

Funds and Project Period

Funds Available Up To
See PFA for more details
Total Direct Costs
- Up to $2.5 million in total direct costs for Implementation Projects
- Up to $300,000 in total costs for Dissemination Projects
Maximum Project Period
Up to 36 months for Implementation Projects and Dissemination Projects