Notice of Upcoming PCORI Funding Announcement

The intent of this limited-competition PFA is to move evidence developed with PCORI-funded research toward practical use in improving health care and health outcomes. PCORI will fund projects that aim to implement patient-centered comparative clinical effectiveness research (CER) results obtained from PCORI-funded research in real-world practice settings, and, in selected cases, projects that focus on the dissemination of these findings.

Applicants will have the opportunity to propose*:

1. Implementation Projects
Implementation Projects may have budgets up to $2.5 million in total direct costs and total project durations of up to 36 months.

2. Dissemination Projects
While this funding opportunity is designed primarily to support implementation projects, PCORI will consider supporting dissemination projects with the primary goal of spreading knowledge and awareness of evidence from PCORI-funded research and increasing targeted end-users’ motivation and ability to use it. Dissemination Projects may have budgets of up to $300,000 in total costs and total project durations of up to 36 months.

Applicant Eligibility: Recipients of PCORI-funded research awards, including Broad PCORI awards, Pilot Projects Program awards, Targeted PCORI awards, Pragmatic Clinical Study awards, and PCORI-funded demonstration projects occurring within PCORnet®, the National Patient-Centered Clinical Research Network infrastructure (e.g., ADAPTABLE and obesity trials), are eligible to respond to this PFA. Additionally:

• Applicants proposing Implementation Projects must have a draft final research report (DFRR) pertaining to the original PCORI-funded research award accepted for entry into PCORI’s peer-review process by the LOI deadline.

*Previous issuances of this PFA included an opportunity for Phased Implementation Projects. The Phased Implementation opportunity is unavailable for this cycle. Updates to future cycles will be announced no later than four weeks before the cycle open date.