|Letters of Intent for this PCORI funding announcement were due Tuesday, February 14, 2017.
Those selected to submit a full application were notified by Wednesday, March 15, 2017.
Full applications were due Wednesday, May 17, 2017, by 5:00 p.m. (ET)
Research Initiative Highlights
This Notice encourages PCORI awardees and their patient and stakeholder partners with strategic plans for disseminating and implementing the research results of their PCORI comparative, clinical effectiveness research (CER) awards to consider applying for this forthcoming funding announcement.
PCORI seeks to support the dissemination and implementation (D&I) of patient-centered CER results obtained from PCORI-funded studies. This opportunity will give PCORI investigators the chance, following the generation of results from their PCORI research award, to propose the next step(s) for making their research results more useful, actionable, and accessible to targeted end-users. This announcement is designed to promote and facilitate the effective and timely use of research evidence in the real world.
Through this PFA, PCORI seeks to fund projects designed to actively disseminate and implement PCORI research results using approaches that are informed and guided by established dissemination and implementation models and frameworks. Successful applications will propose a logical and feasible next step for D&I of clinically meaningful CER finding(s) in order to improve CER finding accessibility, usefulness, uptake, and/or impact among targeted end-users, along with an evaluation plan focusing on an appropriate balance of measurable process and short-, intermediate-, and longer-term outcomes to capture timely information on the effectiveness of the proposed D&I activities.
Specific strategies proposed for disseminating and implementing results of PCORI-funded research projects will vary based on a host of factors, including the finding being disseminated, the population(s) being targeted, and the goals of the D&I effort. PCORI encourages applicants to work closely with relevant stakeholder groups to identify appropriate D&I strategies. All proposed D&I strategies must actively disseminate/implement findings to targeted end-users and evaluate the success of the D&I strategy. Applications proposing to translate or adapt a finding or product without a plan to actively disseminate or implement it will not be considered responsive.
Examples of appropriate projects include, among others, efforts to:
- Develop, demonstrate, and evaluate approaches for incorporating results of PCORI-funded research into decision-making settings for patients, providers, policy makers, and other stakeholders.
- Adapt the content, format, or vehicle for delivering CER research evidence to improve its penetration and use at the policy, health systems, clinical practice, caregiver, and patient levels.
- Demonstrate the capacity and ability to take research results found effective through PCORI research studies “to scale” in diverse settings and populations.
- De-implement or reduce the use of interventions that are not evidence based, have been widely adopted prematurely, or are harmful or wasteful.
PCORI conducts rigorous merit review of all responsive applications received. Please note that the merit review criteria for this announcement are different from those PCORI uses when reviewing research applications.
PCORI’s mission is to improve the quality and relevance of evidence available to help patients, caregivers, clinicians, employers, insurers, and policy makers make informed health decisions. We do this by funding and conducting highly relevant research that is likely to change practice and improve patient outcomes, and by disseminating and promoting the implementation of the results of this research in practice.
This Notice of a PCORI Funding Announcement is provided to allow potential applicants additional time to identify collaborators, obtain stakeholder input on dissemination plans, and develop responsive, high-quality proposals.
Evidence Readiness: Applicants must propose a feasible and logical next step for disseminating and/or implementing a clinically meaningful finding or findings associated with a PCORI-funded CER study. Only projects proposing to disseminate or implement findings from PCORI CER studies that a) tested a research hypothesis and b) evaluated comparative clinical effectiveness of two or more comparators will be responsive to this announcement. (Note: These requirements do not apply to methods studies.)
PCORI Research Awardees: Recipients of PCORI research awards, including Broad PCORI Awards, Pilot Projects Program Awards, Targeted PCORI Awards, Pragmatic Clinical Study Awards, and PCORI-funded demonstration projects occurring within the National Patient-Centered Clinical Research Network (PCORnet) infrastructure (e.g. ADAPTABLE and obesity trials), are eligible to respond to this announcement. Applications associated solely with Eugene Washington PCORI Engagement Awards and Pipeline to Proposal Awards are not eligible for this limited PFA. NOTE: Although eligible to apply, Pilot Projects must still meet all of the PFA requirements in order to be considered responsive. Some of the requirements (e.g., evidence readiness) may be difficult for Pilot projects to satisfy.
Organization: Applications may be submitted by a private sector research organization, including any nonprofit or for-profit organization, as well as public sector research organizations, including university or college hospital or healthcare systems, laboratory or manufacturer, or unit of local, state, or federal government. All US applicant organizations must be recognized by the Internal Revenue Service. Nondomestic components of organization based in the United States and foreign organizations may apply as long as there is demonstrable benefit to the US healthcare system and US efforts in the area of patient-centered research can clearly be shown. Organizations may submit multiple applications for funding. Individuals are not permitted to apply.
Personnel: A Letter of Support is required from the Principal Investigator (PI) of the original PCORI-funded research project if he or she is not the proposed PI of the current application.
Timing: Applicants are required to submit the draft final research report (DFRR) pertaining to their PCORI research award before submitting a full application to this announcement. Applicants may submit the mandatory LOI before submitting their DFRR. Applications submitted prior to PCORI’s receipt of the DFRR, or for which the DFRR is judged to be incomplete or otherwise inadequate by PCORI, will be administratively withdrawn. After submitting their PCORI DFRR, applicants will be eligible to submit an application in response to this limited PFA for two years. During this period of eligibility, applicants will be allowed one opportunity to resubmit an application that was reviewed and not funded in a previous cycle.
- Dissemination and Implementation of PCOR PFA (Cycle 1 2017)
- Dissemination and Implementation of PCOR Application Guidelines (Cycle 1 2017)