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Patient-Centered Outcomes Research Institute

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  • Funding Opportunities
  • Nonsurgical Options for Women with Ur...

Nonsurgical Options for Women with Urinary Incontinence -- Cycle 2 2021

This PCORI Funding Announcement will open on Tuesday, May 4, 2021, with more information about the funding opportunity.


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Notice of Upcoming PCORI Funding Announcement

The Patient-Centered Outcomes Research Institute (PCORI) plans to release a Targeted PCORI Funding Announcement on May 4, 2021, seeking to fund high-quality, comparative effectiveness research projects that focus on efficacious interventions for nonpregnant women with stress, urge, or mixed urinary incontinence (UI), addressing high-priority patient- and stakeholder-guided research questions. This preannouncement is provided to allow potential applicants additional time to identify collaborators; obtain stakeholder input on potential studies; and develop responsive, high-quality proposals.

Research Initiative Highlights

Although there is good evidence for the efficacy of many nonsurgical interventions for UI*, evidence gaps remain, particularly related to direct comparisons of the options. The full range of women affected by UI should be considered, although each application does not need to include all affected populations. If proposed studies include participants with more than one type of UI (stress, urge, or mixed), they should be adequately powered to detect differences by type. Study populations should include appropriate racial and ethnic diversity as well as those for whom access to care is a challenge.

PCORI will accept applications that propose rigorous randomized controlled trials or observational, prospective cohort studies. Applicants can propose to compare two or more of the nonsurgical treatment options for UI, including pharmacological, behavioral, lifestyle, and other nonpharmacological options. Alternative systems approaches that address some of the barriers and dissatisfaction around the various options previously described are also welcomed. Submitted proposals should evaluate both patient-centered functional and adverse outcomes. They may take place in care settings where women receive care for UI.

Applicants may request up to $5 million in direct costs for each project and a maximum study duration of five years. PCORI encourages study proposals with well-justified design and analysis plans that may be completed in a shorter time frame.

More details will be released at a future date.

*See the recently updated systematic evidence review, supported by PCORI through a research partnership with the Agency for Healthcare Research and Quality (AHRQ). Note that AHRQ and PCORI, in collaboration, have both initiated implementation funding initiatives to promote improved, evidence-based care for UI reflecting the findings from this body of evidence. Findings from this upcoming targeted research funding opportunity should further advance care options for this highly prevalent condition.

Key Information
Status 
Upcoming
Cycle 
Cycle 2 2021
Online System Opens 
May 4, 2021
Letter of Intent (LOI) Deadline
June 1, 2021 at 5 pm ET
Application Deadline
August 31, 2021 at 5 pm ET
Merit Review 
December 2021
Awards Announced 
March 2022
Applicant Town Hall Session 

May 10, 2021; 12:00p.m. (ET)

Earliest Start Date 
August 2022
Total Direct Costs 
Up to $5 million
Funds Available Up To 
$40 million
Maximum Project Period 
Up to 5 years
Announcement Type 
Research Award

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Funding Opportunities

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Meetings & Events

April 27
Priorities on the Health Horizon: Informing PCORI's Strategic Plan (Webinar #2)
May 6
Advisory Panel on Healthcare Delivery and Disparities Research Spring 2021 Meeting
May 10
Cycle 2 2021 Nonsurgical Options for Women with Urinary Incontinence -- Applicant Town Hall

PCORI

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Patient-Centered Outcomes
Research Institute

1828 L Street, NW, Suite 900
Washington, DC 20036
Phone: (202) 827-7700 | Fax: (202) 355-9558
info@pcori.org

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