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PCORnet^®, the National Patient-Centered Clinical Research Network is intended to serve as a national resource for conducting rapid, efficient, patient-centered observational and interventional randomized research that improves healthcare delivery and health outcomes.

This announcement describes the scope of work for PCORnet Clinical Research Networks (CRNs) for Phase 3 and available funding to allow for Phase 3’s execution. CRNs are system-based networks that include hospitals and community based-practices, and that may include health plans, all of which routinely and securely collect individual patient-level data. A list of currently funded PCORnet Network Partners can be found at www.pcornet.org.

In Phase 3 of PCORnet, CRNs will ensure the continuity and optimization of critical CRN resources and operations developed in prior phases to facilitate implementation of definitive research studies that are national in scope. Phase 3 will focus on optimizing infrastructure to increase diversity of populations and care settings, efficiently implement research studies addressing PCORI’s Strategic Research Priorities, strengthen patient and stakeholder engagement, and deliver high-fidelity, high integrity data.

Reminder: The primary institution’s Administrative Official must review, authorize, and submit the full application by 5 pm ET on April 6, 2021.