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Patient-Centered Outcomes Research Institute

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  • Funding Opportunities
  • Symptom Management for Patients with ...

Symptom Management for Patients with Advanced Illness -- Cycle 2 2018

Letters of Intent were due Thursday, June 28, 2018, by 5:00 p.m. ET.
Those selected to submit a full application were notified by Monday, July 23, 2018.
Full applications were due Tuesday, September 25, 2018, by 5:00 p.m. ET.


PCORI seeks to fund multiple high-quality clinical studies that compare the effectiveness of evidence-based treatments for relief of common symptoms experienced by patients with serious, advanced illness. For the Cycle 2 2018 PFA, PCORI has refined the requirements for choosing comparative treatments, and removed depression from the symptom list. The goal of this funding initiative is to support patient- and caregiver-centered, comparative clinical effectiveness research to generate important findings that will aid decision making about symptom management in advanced illness.

Symptoms of specific interest for this PFA include pain, fatigue, dyspnea, insomnia, anorexia/cachexia, nausea/vomiting, and anxiety. Study populations should include patients with a serious, life-limiting diagnosis, including but not limited to advanced heart failure, cancer, chronic obstructive pulmonary disease, or neurodegenerative diseases. PCORI is particularly interested in studies that will increase the evidence for treatments that are effective in pediatric and adolescent populations, where fewer studies have been completed. Research questions should incorporate long-term outcomes; a minimum of six months of follow-up of patient participants is encouraged.

Key Information
Status 
Under Review
Cycle 
Cycle 2 2018
Full Announcement 
PDF icon Symptom Management PFA: Cycle 2 2018
Online System Opens 
June 1, 2018
Letter of Intent (LOI) Deadline
June 28, 2018 by 5 p.m. (ET)
Application Deadline
September 25, 2018 by 5 p.m. (ET)
Merit Review 
December 2018
Awards Announced 

April 16, 2019; 12:00 p.m. (ET)

Applicant Town Hall Session 

June 19, 2018; 12:00 p.m. (ET)

Earliest Start Date 
June 2019
Total Direct Costs 
$2 million
Funds Available Up To 
$22 million
Maximum Project Period 
3 years
Announcement Type 
Research Award

Applicant Resources

  • Symptom Management PFA
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Meetings & Events

April 19
Increasing Vaccine Confidence among Long-Term Care Workers: Expedited COVID-19 PFA -- Applicant Town Hall
May 6
Advisory Panel on Healthcare Delivery and Disparities Research Spring 2021 Meeting
May 10
Cycle 2 2021 Nonsurgical Options for Women with Urinary Incontinence -- Applicant Town Hall

PCORI

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Patient-Centered Outcomes
Research Institute

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Washington, DC 20036
Phone: (202) 827-7700 | Fax: (202) 355-9558
info@pcori.org

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