In the Treatment of Anxiety in Children, Adolescents, and/or Young Adults PFA, we seek to fund high quality clinical studies that compare the effectiveness of evidence-based clinical strategies to treat anxiety disorders in children, adolescents, and/or young adults. Clinical strategies to be studied may include pharmacological interventions, psychological interventions, or a combination of both. Each proposed comparator must be clearly defined, evidence-based, widely available, and appropriate for the age range and clinical severity of the study population. The proposed study population should include patients with a confirmed clinical diagnosis of a primary anxiety disorder and who are between 7 and 25 years of age. Studies with a minimum follow-up period of nine months from baseline are sought, with one year of follow-up preferred. In addition, all studies funded through this initiative must include robust sample sizes of at least 300 participants, with sufficient power demonstrated to conduct the proposed analyses.

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Key Dates

Online System Opens
January 3, 2019, 12:00 AM
Letter of Intent Deadline
January 31, 2019, 12:00 AM
Application Deadline
April 24, 2019, 12:00 AM
Awards Announced
<p><a href="/node/14214">November 19, 2019;&nbsp;12:00p.m. (ET)</a></p>

Funds and Project Period

Funds Available Up To

Up to $20 million

Total Direct Costs

$5 million

Maximum Project Period

3.5 years

Applicant Resources


Award Types