PCORI seeks to fund comparative clinical effectiveness research (CER) that will generate new evidence to address important decisional dilemmas regarding treatment options for age-related hearing loss. Proposed interventions may include hearing devices and/or support/rehabilitation services that have either documented evidence of efficacy or of widespread use. PCORI encourages rigorous, high-impact studies that evaluate the comparative effectiveness of hearing loss interventions on relevant patient-centered outcomes to inform decisions encountered by patients, their caregivers, and other healthcare stakeholders. Please note that this PFA is soliciting applications across two funding cycles (Cycles 1 and 2 2019).