These reviews provide answers to specific clinical questions by analyzing published and unpublished results from all relevant studies on a given topic. They identify, select, and summarize findings of available research to make clear what is known about a topic—and what is still not known. Consistent with PCORI and the Agency for Healthcare Research and Quality (AHRQ)’s stakeholder-driven approach, these reviews incorporate patient and stakeholder input throughout their development lifecycle. Stakeholders are involved in the following ways:

  • Nominating relevant and timely topics important to them
  • Identifying key evidence gaps and research questions
  • Helping refine topics chosen for systematic review
  • Reviewing and providing feedback on the proposed Key Questions and parameters of the systematic review and a draft report of review findings

Our goal is to produce up-to-date, actionable evidence to inform important healthcare choices. Based on stakeholder input we commissioned the AHRQ to complete the systematic reviews and systematic review updates listed below:

Posted: June 11, 2019; Updated: October 25, 2022

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