Health and Economic Impact Case Studies
Patient-informed research is more likely to yield results that patients and others can use to inform their healthcare decisions. Broad uptake of evidence from these studies has the potential to improve patient health and other outcomes.
To illustrate, PCORI commissioned a set of case studies to examine the potential health and economic impact of changes in health care practices consistent with the findings of PCORI-funded research. Read about these case studies.
Expanding the Use of Antitumor Necrosis Factor-α (anti-TNF) Therapy for Patients with Crohn's Disease
Crohn's disease, which affects more than 300,000 adults in the United States, can be typically treated with corticosteroids or antitumor necrosis factor-α (anti-TNF) drugs. Expanding the use of anti-TNF drugs to all eligible patients can lead to better patient outcomes.
Using Individual Risk Assessments to Inform Treatment Approaches for Prediabetes
One in three adults in the United States are at risk for diabetes. Identifying which patients would benefit most from treatment may help patients and clinicians, such as doctors or nurses, prevent diabetes among patients at greatest risk.
Using Telemedicine to Deliver Specialty Care for Chronic Skin Diseases
Many patients with psoriasis experience difficulty in accessing dermatologists for care, but recent innovations in telemedicine have created new opportunities for them to access dermatological care.
Comparing Antibiotics for Children with Upper Respiratory Infections
For children with acute upper respiratory tract infections, narrow-spectrum antibiotics worked just as well as broad-spectrum antibiotics at killing the bacteria within three days.
Surveillance Approaches to Detecting Colorectal Cancer Recurrence
Less intensive follow-up testing after surgery for colorectal cancer can reduce the burden on patients, their families, and employers with no significant effect on health outcomes.
Addressing Type 2 Diabetes
Reducing daily blood sugar testing for people with type 2 diabetes who are not on insulin does not affect patients’ health and provides significant savings in healthcare costs.
The Better Form of Antibiotics for Children with Serious Infections
Parents and caregivers can avoid losing thousands of hours of work time per year nationally if children with serious infections receive oral instead of IV antibiotics after they leave the hospital.
Treatment Decision Aid for Patients with Chest Pain Seen in the Emergency Department
Using a simple decision aid can help many patients with chest pain safely avoid unnecessary hospitalizations for follow-up testing. That can mean significant savings.
Helping Stroke Survivors to Stay in Their Homes Longer
For stroke survivors who have atrial fibrillation, treatment with a blood thinner after leaving the hospital can prevent recurrent strokes and give patients more time at home.