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Key Dates

  • Selected HSII Participants Notified by PCORI
    February 2023
  • First HSII Learning Network Meeting
    March 15, 2023
  • HSII Capacity Building Project Proposal Deadline
    April 5, 2023

The Health Systems Implementation Initiative (HSII) is a new PCORI Dissemination and Implementation program funding initiative.

Through HSII, PCORI will provide funding to participating healthcare delivery systems (HSII Participants) to undertake implementation projects in their care delivery settings. These projects will have the goal of promoting the uptake of specific PCORI-funded evidence in practice. PCORI’s Board of Governors has committed up to $50 million to support implementation under HSII.

Selected HSII Participants will be notified by PCORI in February 2023.

Once accepted into the initiative, HSII Participants will have the opportunity to lead efforts to support changes in care delivery to improve health care and patient health outcomes. HSII is intended to facilitate lasting change within participating systems and lay groundwork for broader adoption of evidence-based practices.

Funding Opportunities under HSII

Immediately upon acceptance, HSII Participants will have the opportunity to propose Capacity Building Projects, up to $500,000, to support preparation for implementation and program evaluation under HSII.

Beginning Fall 2023, PCORI anticipates issuing Calls for Proposals for Implementation Projects, providing HSII Participants the opportunity to propose projects to promote the uptake of specific PCORI-funded evidence within their healthcare delivery settings.

View FAQs for HSII

FAQs updated January 26, 2023. See updates regarding the HSII Capacity Building Project opportunity, the HSII Learning Network, and the HSII Master Funding Agreement.


Posted: November 4, 2021; Updated: January 26, 2023

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