PCORI’s Dissemination and Implementation (D&I) Program currently offers three funding opportunities to support projects that actively facilitate the uptake and integration of evidence from PCORI-funded studies, in the context of related evidence, into real-world practice.

PCORI Implementation Funding Opportunities

Examples of PCORI-Funded Implementation Projects

Recently Funded Implementation Projects


Technology-Assisted Implementation of a Mobile Health Intervention for Serious Mental Illness

Ben-Zeev, Dror, PhD

(Awarded 2022, Limited Competition PFA)

This PCORI-funded Implementation Project is expanding the use of a PCORI-tested mHealth program, which includes a patient smartphone app and an online clinician dashboard, to three community mental health agencies in New Hampshire and Missouri. The project team is adapting in-person education and training materials to be delivered remotely, training agency staff to deliver the program and monitor patients' progress and providing ongoing remote practice facilitation support. This project expects to help approximately 4,800 patients with serious mental illness manage their symptoms.


The TRIAD (Treatment Individualized Appendicitis Decision-making) Implementation Program

Flum, David, MD, MPH

(Awarded 2022, Limited Competition PFA)

This PCORI-funded Implementation Project is promoting informed decision-making between antibiotics and appendectomy for eligible patients with appendicitis, based on PCORI-funded research that showed antibiotics were non-inferior to appendectomy in the short term and had helped a majority of patients avoid surgery after a year’s time. The project team is working with 15 diverse hospitals across the U.S. to adopt a program that includes a patient decision support tool, clinician training, and standardized operational protocols. At least 2,500 patients are expected to engage in shared decision-making about treatment options for appendicitis during this project.


All PCORI-Funded Implementation Projects

What's Happening at PCORI?

The Patient-Centered Outcomes Research Institute sends weekly emails about opportunities to apply for funding, newly funded research studies and engagement projects, results of our funded research, webinars, and other new information posted on our site.

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