These reviews provide answers to specific clinical questions by analyzing results from all relevant studies on a given topic. They identify, select, and summarize findings of available research to make clear what is known about a topic—and what is still not known. Consistent with PCORI’s stakeholder-driven approach, these reviews incorporate patient and stakeholder input throughout their development lifecycle. Stakeholders are involved in the following ways:

  • Nominating relevant and timely topics important to them
  • Identifying key evidence gaps and research questions
  • Helping refine topics chosen for systematic review
  • Reviewing and providing feedback on the proposed Key Questions and parameters of the systematic review and a draft report of review findings

Our goal is to produce up-to-date, actionable evidence to inform important healthcare choices. Based on stakeholder input we have developed or collaborated with the Agency for Healthcare Research and Quality (AHRQ) to conduct the systematic reviews listed below.

Posted: June 11, 2019; Updated: April 5, 2024

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