This collection of papers, articles, and commentaries provides insights into PCORI-funded work to advance patient-centered comparative clinical effectiveness research. PCORI is committed to the principles of transparency and openness in all of our work. We encourage authors to make their publications available without a subscription.
PCORI in the Literature
Long- and Short-Term Smoking Cessation Interventions Show Similar Results
Among smokers with chronic obstructive pulmonary disease (COPD), the number who quit after receiving 23 months of nicotine-replacement therapy (NRT) and six counseling sessions was nearly the same as the number who quit after receiving 10 weeks of NRT and four counseling sessions, according to findings of a PCORI-funded study published in JAMA Network Open. While there were insignificant differences in the number of cigarettes smoked per day between the groups, both saw decreases in exposure to unhealthy chemicals and adverse cardiac events. The study followed nearly 400 adults.
Post-Pediatric Discharge Phone Call from Nurses Show Promise
Families with children who were discharged from the hospital and received a one-time telephone call within four days from a nurse to address postdischarge issues needed urgent health care services within the first 30 days almost as often as families who did not receive a phone call, according to a PCORI-funded study report in JAMA Pediatrics. However, parents who received the phone call were able to remember more clinical warning signs within the first two weeks of discharge than other parents. The researchers also suggest that the phone call might enhance standard postdischarge information provided to parents. The study involved 966 children and adolescents under the age of 18.
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Evans E, Whicher D. What Should Oversight of Clinical Decision Support Systems Look Like? AMA Journal Of Ethics. 2018 Sep; 20(9): 857. doi: 10.1001/amajethics.2018.857
Ellerbeck EF, Nollen N, Hutcheson TD, Phadnis M, Fitzgerald SA, Vacek J, SharpeMR, Salzman GA, Richter KP. Effect of Long-term Nicotine Replacement Therapy vs Standard Smoking Cessation for Smokers With Chronic Lung DiseaseA Randomized Clinical Trial. JAMA Network Open. 2018;1(5):e181843. doi:10.1001/jamanetworkopen.2018.1843.
Feemster LC, Saft HL, Bartlett SJ, Parthasarathy S, Barnes T, Calverley P, Curtis JR, Hickam DH, Mularski RA, Au DH, Chlan LL, Reinke LF, Cooke CR, Cox CE, Krishnan JA, Rubin E, Shah S, Sullivan DR, Kross EK; American Thoracic Society Behavioral Sciences and Health Services Research Assembly and Nursing Assembly. Patient-centered Outcomes Research in Pulmonary, Critical Care, and Sleep Medicine. An Official American Thoracic Society Workshop Report. Ann Am Thorac Soc. 2018 Sep;15(9):1005-1015. doi: 10.1513/AnnalsATS.201806-406WS. PubMed PMID: 30168741.