This collection of papers, articles, and commentaries provides insights into PCORI-funded work to advance patient-centered comparative clinical effectiveness research. PCORI is committed to the principles of transparency and openness in all of our work. We encourage authors to make their publications available without a subscription.
PCORI in the Literature
Helping Children with Medicaid Initiate the Referral Process for Mental Health Care
Many children who are Medicaid participants with mental health problems don’t receive the care they need, in part because families must first undergo a complex referral process to community mental health clinics (CMHCs) for diagnostic and therapeutic mental health services. Reporting in Pediatrics, this study found that compared with parents who had usual referrals, those who had video chat referrals were three times more likely to finish screening for specialty mental health care at the CMHC.
Depression Drug Offers Modest Outcomes Over Cognitive Therapy for Patients Undergoing Hemodialysis
Patients undergoing long-term treatment for kidney failure often also experience depression. In a PCORI-funded study, more patients reported modest improvements in their depressive symptoms with the drug sertraline than patients who received cognitive behavioral therapy, the study’s researchers report in the Annals of Internal Medicine. However, patients who opted for the daily medication experienced more adverse events, such as nausea and dizziness.
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Nestsiarovich A, Kerner B, Mazurie AJ, Cannon DC, Hurwitz NG, Zhu Y, Nelson SJ, Oprea TI, Unruh ML, Crisanti AS, Tohen M, Perkins DJ, Lambert CG. Comparison of 71 bipolar disorder pharmacotherapies for kidney disorder risk: The potential hazards of polypharmacy. J Affect Disord. 2019 Apr 8;252:201-211. doi:10.1016/j.jad.2019.04.009. [Epub ahead of print] PubMed PMID: 30986735.
Aslakson RA, Isenberg SR, Crossnohere NL, Conca-Cheng AM, Moore M, Bhamidipati A, Mora S, Miller J, Singh S, Swoboda SM, Pawlik TM, Weiss M, Volandes A, Smith TJ, Bridges JFP, Roter DL. Integrating Advance Care Planning Videos into Surgical Oncologic Care: A Randomized Clinical Trial. J Palliat Med. 2019 Apr 9. doi:10.1089/jpm.2018.0209. [Epub ahead of print] PubMed PMID: 30964385.
Schwartz PH, Imperiale TF, Perkins SM, Schmidt KK, Althouse S, Rawl SM. Impact of including quantitative information in a decision aid for colorectal cancer screening: A randomized controlled trial. Patient Educ Couns. 2019 Apr;102(4):726-734. doi: 10.1016/j.pec.2018.11.010. Epub 2018 Nov 27. PubMed PMID: 30578103.
Subramanian L, Zhao J, Zee J, Knaus M, Fagerlin A, Perry E, Swartz J, McCall M, Bryant N, Tentori F. Use of a Decision Aid for Patients Considering Peritoneal Dialysis and In-Center Hemodialysis: A Randomized Controlled Trial. Am J Kidney Dis. 2019 Apr 3. pii: S0272-6386(19)30160-X. doi: 10.1053/j.ajkd.2019.01.030. [Epub ahead of print] PubMed PMID: 30954312.
Garland SN, Xie SX, DuHamel K, Kantoff P, Bao T, Mao JJ, et al. Acupuncture Versus Cognitive Behavioral Therapy for Insomnia in Cancer Survivors: A Randomized Clinical Trial. 2019 Apr. doi.org/10.1093/jnci/djz050.