This collection of papers, articles, and commentaries provides insights into PCORI-funded work to advance patient-centered comparative clinical effectiveness research. PCORI is committed to the principles of transparency and openness in all of our work. We encourage authors to make their publications available without a subscription.
PCORI in the Literature
Nondrug Therapies for Treating Insomnia in Patients With Cancer
Thirty to 50 percent of patients with cancer experience insomnia, often caused by medications or anxiety about their diagnosis. This PCORI-funded Sloan Kettering Institute for Cancer Research-based project found that patients like these might see improvement in quality of sleep and quality of life through nondrug treatments like acupuncture and cognitive behavioral therapy (CBT). Researchers say in an article in the Journal of the National Cancer Institute that while both therapies seem to help, CBT was more effective.
Helping Children with Medicaid Initiate the Referral Process for Mental Health Care
Many children who are Medicaid participants with mental health problems don’t receive the care they need, in part because families must first undergo a complex referral process to community mental health clinics (CMHCs) for diagnostic and therapeutic mental health services. Reporting in Pediatrics, this study found that compared with parents who had usual referrals, those who had video chat referrals were three times more likely to finish screening for specialty mental health care at the CMHC.
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Wernli KJ, Ichikawa L, Kerlikowske K, Buist DSM, Brandzel SD, Bush M, Johnson D, Henderson LM, Nekhlyudov L, Onega T, Sprague BL, Lee JM, Lehman CD, Miglioretti DL. Surveillance Breast MRI and Mammography: Comparison in Women with a Personal History of Breast Cancer. Radiology. 2019 Jun 4:182475. doi:10.1148/radiol.2019182475. [Epub ahead of print] PubMed PMID: 31161975.
Minneci PC, Cooper JN, Leonhart K, Nacion K, Sulkowski J, Porter K, Wei L, Deans KJ. Effects of a Patient Activation Tool on Decision Making Between Surgery and Nonoperative Management for Pediatric Appendicitis: A Randomized Clinical Trial. JAMA Netw Open. 2019 Jun 5;2(6):e195009. doi: 10.1001/jamanetworkopen.2019.5009. PubMed PMID: 31173118
Federman AD, O’Conor R, Mindlis I, et al. Effect of a Self-management Support Intervention on Asthma Outcomes in Older Adults: The SAMBA Study Randomized Clinical Trial. JAMA Intern Med. Published online June 10, 2019. doi:10.1001/jamainternmed.2019.1201.
McGlynn EA, Adams JL, Kramer J, Sahota AK, Silverberg MJ, Shenkman E, Nelson DR. Assessing the Safety of Direct-Acting Antiviral Agents for Hepatitis C. JAMA Netw Open. 2019 Jun 5;2(6):e194765. doi: 10.1001/jamanetworkopen.2019.4765. PubMed PMID: 31173117. Open access
Laudenslager ML, Simoneau TL, Mikulich-Gilbertson SK, Natvig C, Brewer BW, Sannes TS, Kilbourn K, Gutman J, McSweeney P. A Randomized Control Trial of Stress Management for Caregivers of Stem Cell Transplant Patients: Effect on Patient Quality of Life and Caregiver Distress. Psychooncology. 2019 May 25. doi: 10.1002/pon.5126. [Epub ahead of print] PubMed PMID: 31127974.