This collection of papers, articles, and commentaries provides insights into PCORI-funded work to advance patient-centered comparative clinical effectiveness research. PCORI is committed to the principles of transparency and openness in all of our work. We encourage authors to make their publications available without a subscription.
PCORI in the Literature
Nondrug Therapies for Treating Insomnia in Patients With Cancer
Thirty to 50 percent of patients with cancer experience insomnia, often caused by medications or anxiety about their diagnosis. This PCORI-funded Sloan Kettering Institute for Cancer Research-based project found that patients like these might see improvement in quality of sleep and quality of life through nondrug treatments like acupuncture and cognitive behavioral therapy (CBT). Researchers say in an article in the Journal of the National Cancer Institute that while both therapies seem to help, CBT was more effective.
Helping Children with Medicaid Initiate the Referral Process for Mental Health Care
Many children who are Medicaid participants with mental health problems don’t receive the care they need, in part because families must first undergo a complex referral process to community mental health clinics (CMHCs) for diagnostic and therapeutic mental health services. Reporting in Pediatrics, this study found that compared with parents who had usual referrals, those who had video chat referrals were three times more likely to finish screening for specialty mental health care at the CMHC.
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Richmond J, Mangrum R, Wang G, Maurer M, Sofaer S, Yang M, Carman KL. An informed public's views on reducing antibiotic overuse. Health Serv Res. 2019 Jun 6. doi: 10.1111/1475-6773.13175. [Epub ahead of print] PubMed PMID: 31172520.
Hahn EE, Munoz-Plaza CE, Schottinger JE, Brasfield FM, Gould MK, Parry C. Developing innovative models of care for cancer survivors: use of implementation science to guide evaluation of appropriateness and feasibility. Support Care Cancer. 2019 May;27(5):1737-1745. doi: 10.1007/s00520-018-4425-5. Epub 2018 Aug 24. PubMed PMID: 30143893.
Sox HC, Aerts M, Haasenriter J. Applying a Clinical Decision Rule for CAD in Primary Care to Select a Diagnostic Test and Interpret the Results. Am Fam Physician. 2019 May 1;99(9):584-586. PubMed PMID: 31038896.
Pinsky PF, Black A, Daugherty SE, Hoover R, Parnes H, Smith ZL, Eggener S, Andriole GL, Berndt SI. Metastatic prostate cancer at diagnosis and through progression in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. Cancer. 2019 May 8. doi: 10.1002/cncr.32176. [Epub ahead of print] PubMed PMID: 31067347.
Whitlock EP, Selby JV, Dunham KM, Fernandez A, Forsythe LP, Norquist G. Examining the role of funders in ensuring value and reducing waste in research: An organizational case-study of the Patient-Centered Outcomes Research Institute. F1000Res. 2019 Mar 14;8:288. doi: 10.12688/f1000research.18471.1. eCollection 2019. PubMed PMID: 31131095; PubMed Central PMCID: PMC6518438.
Broitman M, Sox HC, Slutsky J. A Model for Public Access to Trustworthy and Comprehensive Reporting of Research. JAMA. 2019 Mar 28. doi: 10.1001/jama.2019.2807. [Epub ahead of print] PubMed PMID: 30920580.
Glasgow RE, Harden SM, Gaglio B, Rabin B, Smith ML, Porter GC, Ory MG and Estabrooks PA. RE-AIM Planning and Evaluation Framework: Adapting to New Science and Practice With a 20-Year Review. Front. Public Health. 2019 Mar;7:64. doi: 10.3389/fpubh.2019.00064.
Forsythe LP, Carman KL, Szydlowski V, Fayish L, Davidson L, Hickam DH, Hall C, Bhat G, Neu D, Stewart L, Jalowsky M, Aronson N, Anyanwu CU. Patient Engagement In Research: Early Findings From The Patient-Centered Outcomes Research Institute. Health Aff (Millwood). 2019 Mar;38(3):359-367. doi: 10.1377/hlthaff.2018.05067. PubMed PMID: 30830822.
Whitlock EP, Dunham KM, DiGioia K, Lazowick E, Gleason TC, Atkins D. Noncommercial US Funders' Policies on Trial Registration, Access to Summary Results, and Individual Patient Data Availability. JAMA Netw Open. 2019 Jan 4;2(1):e187498. doi: 10.1001/jamanetworkopen.2018.7498. PubMed PMID: 30681715.
Mason NR, Sox HC, Whitlock EP. A Patient-Centered Approach to Comparative Effectiveness Research Focused on Older Adults: Lessons From the Patient-Centered Outcomes Research Institute. J Am Geriatr Soc. 2018 Dec 26. doi:10.1111/jgs.15655. [Epub ahead of print] PubMed PMID: 30586155.