- 2023 Annual Meeting
- The PCORI Strategic Plan
- Clinical Effectiveness and Decision Science
- Dissemination and Implementation
- Evaluation and Analysis
- Healthcare Delivery and Disparities Research
- PCOR Infrastructure & Innovation
- Our Vision & Mission
- Financial Statements and Reports
- The PCORI Strategic Plan
- Board of Governors
- Methodology Committee
- Authorizing Law
- Evaluating Our Work
- PCORI's Advisory Panels
- Procurement Opportunities
Past Opportunities to Provide Input
- Stakeholder Views on Components of 'Patient-Centered Value' in Health and Health Care (2023)
- PCORI's Proposed Research Agenda (2021-2022)
- Proposed National Priorities for Health (2021)
- Proposed Principles for the Consideration of the Full Range of Outcomes Data in PCORI-Funded Research (2020)
- Proposed New PCORI Methodology Standards (2018)
- Data Access and Data Sharing Policy: Public Comment (2017)
- Proposed New PCORI Methodology Standards (2017)
Comment on the Proposed New and Revised PCORI Methodology Standards (2016)
- 1. Standards for Formulating Research Questions
- 10: Standards for Studies of Diagnostic Tests
- 12. Standards on Research Designs Using Clusters
- 13: General Comments on the Proposed Revisions to the PCORI Methodology Standards
- 2: Standards Associated with Patient-Centeredness
- 3: Standards for Data Integrity and Rigorous Analysis
- 4: Standards for Preventing and Handling Missing Data
- 5: Standards for Heterogeneity of Treatment Effects
- 6: Standards for Data Registries
- 7: Standards for Data Networks as Research-Facilitating Structures
- 8. Standards for Causal Inference Methods
- 9. Standards for Adaptive Trial Designs
- Peer-Review Process Comments (2014)
- Draft Methodology Report Public Comment Period (2012)
- Past Opportunities to Provide Input
WASHINGTON, DC — Recognizing the persistent disparities in controlling asthma among African-American and Hispanic/Latino populations in the United States, the Patient-Centered Outcomes Research Institute (PCORI) today issued a call for research proposals to provide new information on ways to solve this problem.
PCORI will invest up to $17 million in patient-centered outcomes research projects that evaluate comprehensive and coordinated approaches to reducing poor health and other complications related to uncontrolled asthma in these target populations, as well as improving both patients' and their healthcare providers' adherence to treatment guidelines. Studies might incorporate interventions at the community, home, and health system levels and assess combinations of patient education tools, asthma medications, team-based approaches, or interventions delivered in homes or other locations outside medical facilities.
PCORI also is looking for proposals that will examine outcomes that matter most to patients and their families, such as missed days of school or work, visits to emergency departments, limitations on individuals' activities, patients' and families' ability to manage symptoms themselves outside of medical facilities, and their overall quality of life.
Those interested in this PCORI Funding Announcement (PFA) must submit letters of intent (LOIs) by Thursday, Aug. 1, and applications by Wednesday, Sept. 18. Application guidelines and templates will be available on Monday, July 1, in the Funding Opportunities section of PCORI's website. PCORI will host an informational webinar on Tuesday, July 9, for interested applicants.
"We heard from patients, healthcare professionals, and other stakeholder that improving asthma care among racial and ethnic minority groups who are the worst affected is a high priority area of concern, and we responded," said PCORI Executive Director Joe Selby, MD, MPH. “Through this funding opportunity, we’re seeking answers to several historic and vexing questions about disparities in asthma control, and the information generated could help millions of individuals and their families achieve improved health and better quality of life."
Asthma affects nearly 26 million Americans and disproportionately affects racial and ethnic minorities. African Americans are among those at highest risk, with almost 4.5 million people -- approximately 12 percent -- affected in 2010. They experience significantly higher asthma-related illness and death rates than do white Americans. About 3.6 million Hispanics and Latinos/Latinas in the United States -- some 7 percent -- reported having asthma in 2010.
African-American children are three times as likely as white children and Hispanic/Latino children are almost twice as likely to seek asthma care in emergency departments and to have an asthma-related hospital stay. Both these groups of children have a lower likelihood than white children to be prescribed asthma treatment and to follow it when they are.
Not all asthma care may be optimal for all populations, and treatments beneficial to some groups may be less beneficial to others. Moreover, much research shows that disparities in health and health care are generally due to multiple factors, health-related as well as social and economic.
The asthma announcement is the first of a series of planned PFAs to result from PCORI’s efforts to issue funding opportunities to support research that will answer patients’ questions about healthcare options in specific, high-impact research topic areas. PCORI identified an initial set of such topics by reviewing previous efforts to identify and prioritize gaps in comparative effectiveness research and then empaneled multi-stakeholder workgroups to help refine the list.
PCORI also recently signed an agreement with the National Institute on Aging, part of the National Institutes of Health, to form a partnership to fund a major intervention study aimed at preventing injuries from falls in older adults. And PCORI's Board of Governors today approved the development of an initiative to fund research projects focused on uterine fibroids in women, working in collaboration with the Agency for Healthcare Research and Quality. Additional targeted PFAs are expected to be issued later this year.
The Patient-Centered Outcomes Research Institute (PCORI) is an independent nonprofit organization authorized by Congress in 2010. Its mission is to fund research that will provide patients, their caregivers and clinicians with the evidence-based information needed to make better-informed healthcare decisions. PCORI is committed to continually seeking input from a broad range of stakeholders to guide its work.
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The Patient-Centered Outcomes Research Institute sends weekly emails about opportunities to apply for funding, newly funded research studies and engagement projects, results of our funded research, webinars, and other new information posted on our site.