- The PCORI Strategic Plan
- Our Programs
- Our Vision & Mission
- Financial Statements and Reports
- The PCORI Strategic Plan
- Board of Governors
- Methodology Committee
- Authorizing Law
- Evaluating Our Work
- PCORI's Advisory Panels
- Procurement Opportunities
Past Opportunities to Provide Input
- Patient-Centered Economic Outcomes Landscape (2023-2024)
- Systematic Review of Audio Care for the Management of Mental Health and Chronic Conditions (2023) -- Draft Key Questions
- Proposed New Methodology Standards for Usual Care as a Comparator (2023)
- Stakeholder Views on Components of 'Patient-Centered Value' in Health and Health Care (2023)
- PCORI's Proposed Research Agenda (2021-2022)
- Proposed National Priorities for Health (2021)
- Proposed Principles for the Consideration of the Full Range of Outcomes Data in PCORI-Funded Research (2020)
- Proposed New PCORI Methodology Standards (2018)
- Data Access and Data Sharing Policy: Public Comment (2017)
- Proposed New PCORI Methodology Standards (2017)
Comment on the Proposed New and Revised PCORI Methodology Standards (2016)
- 1. Standards for Formulating Research Questions
- 10: Standards for Studies of Diagnostic Tests
- 12. Standards on Research Designs Using Clusters
- 13: General Comments on the Proposed Revisions to the PCORI Methodology Standards
- 2: Standards Associated with Patient-Centeredness
- 3: Standards for Data Integrity and Rigorous Analysis
- 4: Standards for Preventing and Handling Missing Data
- 5: Standards for Heterogeneity of Treatment Effects
- 6: Standards for Data Registries
- 7: Standards for Data Networks as Research-Facilitating Structures
- 8. Standards for Causal Inference Methods
- 9. Standards for Adaptive Trial Designs
- Peer-Review Process Comments (2014)
- Draft Methodology Report Public Comment Period (2012)
- Past Opportunities to Provide Input
WASHINGTON, DC — The Patient-Centered Outcomes Research Institute (PCORI) this week shared details about a forthcoming $63 million funding opportunity for comparative clinical effectiveness research (CER) studies to reduce inequities in maternal health care and outcomes.
The Partnering Research and Community Organizations for Novel Health Equity Research: Addressing Health Systems Factors and Social Determinants of Maternal Health Targeted PCORI Funding Announcement, or Partner Targeted PFA, will focus on comparing multicomponent, multilevel interventions that simultaneously address clinical conditions and social determinants of health to improve maternal health outcomes, a high-priority research focus for PCORI. This funding opportunity also is part of PCORI’s commitment to supporting initiatives that further progress toward achieving health equity, one of the overarching priorities that guide PCORI’s work.
“Eliminating the significant disparities in maternal outcomes that persist in the United States requires evidence-based solutions that comprehensively address both the social and clinical needs of communities disproportionately experiencing adverse outcomes,” said PCORI Executive Director Nakela L. Cook, M.D., M.P.H. “This is why PCORI intends to fund CER studies in which community organizations are full partners in the work, providing leadership alongside researchers from study ideation through planning and conduct of the research.”
PCORI is sharing details about the funding opportunity in a pre-announcement to allow potential applicants ample notice to engage; obtain stakeholder input on potential CER study questions and designs; and gather other information and resources to develop responsive, high-quality proposals. PCORI will begin accepting Letters of Intent from prospective applicants to the Partner Targeted PFA in January 2023.
Among the details provided in the pre-announcement, PCORI shared that studies may focus on pre- and/or postnatal care and should include at least one of each of the following types of interventions: health system strategies to address disparities in maternal health outcomes and strategies to address social determinants of health.
PCORI will seek proposals from applicants with established researcher-community partnerships. Community organizations may include, for example, those that provide social services to address specific needs such as housing, food, and transportation; faith-based organizations; or organizations with relevant community data.
“Community-based organizations bring deep knowledge of residents’ lived experience as well as needs and factors that affect their health, access to care, and ability to take advantage of available care options,” Cook said. “This knowledge and experience are crucial to designing and conducting studies with greater chances of success to improve maternal outcomes and help move us toward a health system that eliminates inequities for all.”
Each awardee under the Partner Targeted PFA will have the opportunity to conduct one or more CER studies with their funds. This flexible structure will enable awardees to address more than one priority issue in their community. Each award will have a total funding opportunity of up to $21 million.
In addition to research costs, research funding will support mentoring opportunities for investigators from populations and communities traditionally underrepresented and underserved in health research, and awardees’ participation in a learning network across awardees.
The Patient-Centered Outcomes Research Institute (PCORI) is the nation’s leading funder of patient-centered comparative clinical effectiveness research (CER). By comparing two or more health or healthcare approaches, CER generates evidence that helps people make better-informed decisions and improves healthcare delivery and outcomes. PCORI takes a holistic approach to its work, ensuring that patients and other health decision makers are engaged as partners throughout the research process, supporting dissemination and implementation of results in practice and strengthening clinical research infrastructure to advance patient-centered CER. PCORI is an independent, non-profit organization authorized by Congress.