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WASHINGTON, DC—The Patient-Centered Outcomes Research Institute (PCORI) today launched a public comment period on five proposed National Priorities for Health that represent an ambitious approach to frame PCORI’s funding of patient-centered comparative clinical effectiveness research (CER) in the years ahead. Public comment on the proposed priorities, which were developed with input from patients and healthcare decision makers, will be open June 28 through Aug. 27 on PCORI’s website.

Please note that the 60-day public comment period on PCORI's proposed National Priorities for Health ended on August 27, 2021. View submitted comments here.

Following its reauthorization by Congress, PCORI’s Board of Governors embarked on a strategic initiative to reimagine the organization’s current National Priorities and Research Agenda, which have guided PCORI’s work for nearly 10 years.

"Congress recognized the importance of establishing overarching goals for PCORI’s unique and important place in healthcare and health research ecosystems and tasked the Board of Governors with leading this strategic process," said Board Chairperson Christine Goertz, DC, PhD. "The proposed National Priorities for Health reflect a strategic, inclusive approach responsive to current health challenges and reflect the evolution of our priorities from categories of research to long-term goals for health outcomes that PCORI aims to accomplish through research and other strategic imperatives."

The five proposed National Priorities for Health are wide-ranging areas that reflect what is most important to patients, stakeholders, and the broader healthcare community. Conceived as integrated elements, they are:

  • Achieve Health Equity 
  • Increase Evidence for Existing Interventions and Emerging Innovations in Health
  • Enhance Infrastructure to Accelerate Patient-Centered Outcomes Research 
  • Advance the Science of Dissemination, Implementation, and Health Communication 
  • Accelerate Progress Toward an Integrated Learning Health System 

PCORI’s Board of Governors approved posting the proposed National Priorities for Health for a 60-day public comment period at its June meeting. A June 29 webinar will introduce PCORI’s proposed National Priorities for Health to stakeholders.

“Hearing from our stakeholders is critical to ensure that PCORI’s proposed National Priorities for Health and forthcoming Research Agenda address our nation’s most pressing health needs,” said PCORI Executive Director Nakela L. Cook, MD, MPH.  “With this important stakeholder guidance, we look forward to furthering our mission to help people make informed health decisions and improve healthcare delivery and health outcomes.”

PCORI’s Board of Governors expects to finalize the proposed National Priorities for Health in fall 2021. The priorities will serve as the foundation for developing PCORI’s Research Agenda, which also will be presented for public comment. PCORI plans several initiatives to allow stakeholders to continuously provide their input and feedback on aspects of the strategic planning process of which the National Priorities for Health and Research Agenda are a part.

PCORI invites stakeholders to comment on the proposed National Priorities for Health on PCORI’s website and to register for the June 29 webinar featuring Cook.



The Patient-Centered Outcomes Research Institute (PCORI) is an independent nonprofit organization authorized by Congress in 2010. Its mission is to fund research that will provide patients, their caregivers and clinicians with the evidence-based information needed to make better-informed healthcare decisions. PCORI is committed to continually seeking input from a broad range of stakeholders to guide its work.

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